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2012年發(fā)表的論文

1.Nguyen TV, Angkasekwinai P,Dou H, Lin FM,Lu LS, Cheng J, Chin YE, Dong C, Yeh ET. SUMO-Specific Protease 1 Is Critical for Early Lymphoid Development through Regulation of STAT5 Activation. Molecular Cell. 45:210-221. 2012.

2.Zhou J, Fan Q, Zhang Z, Zou Y, Cai R, Wang Q, Zuo Y, and Cheng J. SENP1 Deficiency Promotes ER Stress-Induced Apoptosis by Increasing XBP1 SUMOylation. Cell Cycle. 11:1118-1122 . 2012.(重點(diǎn)實(shí)驗(yàn)室標(biāo)注)
3.Wang Q, Xia N, Li T, Xu Y, Zou Y, Zuo Y, Fan Q, Bawa-Khalfe T, Yeh ET, Cheng J.SUMO-specific protease 1 promotes prostate cancer progression and metastasis. Oncogene. 2012 Jun 25. doi: 10.1038/onc.2012.250. [Epub ahead of print] (重點(diǎn)實(shí)驗(yàn)室標(biāo)注)
4.Wang Y, Yang J, Yi J. Redox sensing by proteins: oxidative modifications on cysteines and the consequent events. Antioxid Redox Signal. 2012, 16(7): 649-57, (Forum Review Article). 
5.Wang Y, Yang J, Yang K, Cang H, Huang XZ, Li H, Yi J. The biphasic redox sensing of SENP3 accounts for the HIF-1 transcriptional activity shift by oxidative stress. Acta Pharmacol Sin. 2012, 33(7):953-63(重點(diǎn)實(shí)驗(yàn)室標(biāo)注)
6.Ye J, Mancuso A, Tong X, Ward PS, Fan J, Rabinowitz JD, Thompson CB. Pyruvate kinase M2 promotes de novo serine synthesis to sustain mTORC1 activity and cell proliferation. Proc Natl Acad Sci U S A. 2012 May 1;109(18):6904-9.
7.Mao Y, Keller DT, Garfield DH, Shen KW*, Wang JH*. Stromal Cells in Tumor Microenvironment and Breast Cancer. Cancer and Metastasis Reviews. 2012, in press.(IF 10.6).
8.Hao MG, Zheng JH, Hou KL, Wang JL, Chen XS, Lu XJ,Bo JJ, Xu C, Shen KW, Wang JH*. Role of chemokine receptor CXCR7 in bladder cancer progression. Biochemical Pharmacology. 2012, 84:2204-14. (IF 4.8)
9.Zheng JH, Xiong D, Sun XQ, Wang JL, Hao MG, Ding T, Xiao G, Wang XM, Mao Y, Fu YJ, Shen KW, Wang JH*. Signification of hypermethylated in cancer 1(HIC1)as tumor suppressor gene in tumor progression. Cancer Microenviroment. 2012, 5:285–93.
10.Cao XY, Shen MW, Zhang XD, Hu J, Wang JH*, Shi XY*. Effect of the surface functional groups of dendrimer-entrapped gold nanoparticles on the improvement of polymerase chain reaction. (*Co-corresponding author). Electrophoresis. 2012,33(16):2598-603. (IF3.5)
11.Guo R, Yao Y, Wang SH, Shen MW, Zhang YH, Baker JR, Wang JH*, Shi XY*. Synthesis of glycoconjugated poly(amindoamine) dendrimers for targeting human liver cancer cells. (*Co-corresponding author). RSC Advances. 2012, 2: 99-102.
12.Tong WW, Cao XY, Wen SH, Guo R, Shen MW, Wang JH*, Shi XY*. Improving the specificity and efficiency of polymerase chain reaction using polyethyleneimine-based derivatives and hybrid nanocomposites.  (*Co-corresponding author). International Journal of Nanomedicine. 2012,7:1069-78. (IF 3.2)
13.Peihua Ni, Hong Xu ,  Changqiang Chen,  Jiayi Wang, Xiangfan Liu,  Yiqun Hu,  Qishi Fan, Zhaoyuan Hou, Yang Lu    2012    Serum starvation induces DRAM expression in liver cancer cells via histone modifications within its promoter locus. PloS ONE   (Accepted)
14.Huang C, Li WG, Zhang XB, Wang L, Xu TL, Wu D#, Li Y#. Alpha-asarone from Acorus gramineus alleviates epilepsy by modulating A-Type GABA receptors.Neuropharmacology,2012, 65C:1-11. doi: 10.1016/j.neuropharm.2012.09.001.
15.Wang L, Li WG, Huang C, Zhu MX, Xu TL, Wu DZ, Li Y#. Subunit-specific inhibition of glycine receptors by curcumol.J Pharmacol Exp Ther. 2012 ,343(2):371-379. doi: 10.1124/jpet.112.195669.
16.Xu NJ, Henkemeyer M. Ephrin reverse signaling in axon guidance and synaptogenesis. Semin Cell Dev Biol, 23: 58-64 (2012).
17.Li D, Wang Y, Zhang L, Luo X, Li J, Chen X, Niu H, Wang K, Sun Y, Wang X, Yan Y, Chai W, Gartner TK, Liu J. Roles of purinergic receptor P2Y, G protein-coupled 12 in the development of atherosclerosis in apolipoprotein E-deficient mice.Arterioscler Thromb Vasc Biol. 2012 Aug;32(8):e81-9. Epub 2012 May 24. (重點(diǎn)實(shí)驗(yàn)室標(biāo)注)
18.Niu H, Xu Z, Li D, Zhang L, Wang K, Taylor DB, Liu J, Gartner TK..Peptide LSARLAF induces integrin β3 dependent outside-in signaling in platelets. Thromb Res. 2012 Aug;130(2):203-9. Epub 2012 Apr 5. (重點(diǎn)實(shí)驗(yàn)室標(biāo)注)
19.Haixia Niu, Ph.D.,Xue Chen,Ralph Gruppo,Ding Li,Yanhua Wang,Lin Zhang,Kemin Wang,Weiran Chai,Yueping Sun,Zhongren Ding,T. Kent Gartner,Junling Liu. Integrin αIIb-Mediated PI3K/Akt Activation in Platelets. (重點(diǎn)實(shí)驗(yàn)室標(biāo)注)
20.Yang Y, Yu Y, Cheng J, Liu Y, Liu DS, Wang J, Zhu MX, Wang R, and Xu TL. Highly conserved salt bridge stabilizes rigid signal patch at extracellular loop critical for surface expression of acid-sensing ion channels. J Biol Chem, 287 (18):14443-14455, 2012.
21.Duan B, Liu DS, Huang Y, Zeng WZ. Wang X, Yu H, Zhu MX, Chen ZY, and Xu TL. PI3-kinase/Akt pathway-regulated membrane insertion of acid-sensing ion 1a underlies BDNF-induced pain hypersensitivity. J Neurosci. 32 (18):6351-6363, 2012.
22.Zeng WZ, and Xu TL. Proton production, regulation and pathophysiological roles in the mammalian brain. Neurosci Bull, 28 (1):1-13, 2012.
23.Li WG, and Xu TL. Emerging approaches to probing ion channel structure and function. Neurosci Bull, 28(4):351-74, 2012.
24.Asish K Ghosh, Swati Bhattacharyya, Jun Wei, Robert Lafyatis, Giuseppina Farina, Jianxiu Yu, Bayar Thimmapaya and John Varga. The coactivator and acetyltransferase p300is elevated in scleroderma biopsies and is induced by transforming growth factor-ß: implications for fibrosis. Journal of Investigative Dermatology, 2012 (In press).
25.He Z, SS Zhang, J Yu, and GS Feng. Metabolic effects of neural and pancreatic Shp2. A chapter in the Book “Protein Tyrosine Phosphatase Control of Metabolism”, Springer Press, Edited by K Bence. 2012 (In press).
26.Huang J, Yan J, Zhang J, Zhu S, Wang Y, Shi T, Zhu C, Chen C, Liu X, Cheng J, Mustelin T, Feng GS, Chen G, Yu J*. SUMO1 modification of PTEN regulates tumorigenesis by controlling its association with the plasma membrane.Nat Commun. 2012 Jun 19; 3:911. doi: 10.1038/ncomms1919.  (IF=7.39) Recommended by Faculty of 1000. (重點(diǎn)實(shí)驗(yàn)室標(biāo)注)
27.Liu X, Wang Y, Sun Q, Yan J, Huang J, Zhu S, Yu J*. Identification of microRNA transcriptome involved in human natural killer cell activation.Immunol Lett. 2012 Apr 30;143(2):208-17. (重點(diǎn)實(shí)驗(yàn)室標(biāo)注)
28.Yu J, Zhang D, Liu J, Li J, Yu Y, Wu XR, Huang C. RhoGDI SUMOylation at Lys-138 Increases Its Binding Activity to Rho GTPase and its Inhibiting Cancer Cell Motility.J Biol Chem. 2012 Apr 20;287(17):13752-60. Epub 2012 Mar 5. 
29.Liu J, Zhang D, Luo W, Yu J, Li J, Yu Y, Zhang X, Chen J, Wu XR, Huang C. E3 Ligase Activity of XIAP RING Domain Is Required for XIAP-Mediated Cancer Cell Migration, but Not for Its RhoGDI Binding Activity.PLoS One. 2012;7(4):e35682. Epub 2012 Apr 19. 
30.Lu S, Huang W, Li X, Huang Z, Liu X, Chen Y, Shi T, Zhang J*. Insights into the Role of Magnesium Triad in myo-Inositol Monophosphatase: Metal Mechanism, Substrate Binding and Lithium Therapy. J Chem Inf Model. 2012, 52, 2398-2409. ( IF=4.675) (重點(diǎn)實(shí)驗(yàn)室標(biāo)注)
31.Huang Z, Jiang H, Liu X, Chen Y, Wang Q, Huang W, Shi T, Zhang J*. HEMD: an integrated tool of human epigenetic enzymes and chemical modulators for therapeutics. PLOS ONE. 2012, 7, e39917. (IF=4.092)
32.Tang J, Huang Z, Chen Y, Zhang Z, Liu G, Zhang J*. A novel inhibitor of human La protein with anti-HBV activity discovered by structure-based virtual screening and in vitro evaluation. PLOS ONE. 2012, 7, e36363. (IF=4.092)
33.Liu X, Liu B, Huang Z, Shi T, Chen Y, Zhang J*. SPPS: a sequence-based method for predicting probability of protein-protein interaction partners. PLOS ONE. 2012, 7, e30938. (IF=4.092)
34.Shu Zhu, Wen Pan, Xinyang Song, Yan Liu, Xinrui Shao, Yuanjia Tang, Dong Liang, Dongyi He, Honglin Wang, Wenjun Liu, Yufang Shi, John B Harley, Nan Shen & Youcun Qian. The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-α. Nature Medicine, Published online: 03 June 2012 doi:10.1038/nm.2815. IF: 22.462
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