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主要致力于感染與免疫研究。以人類重大感染性疾病為研究對象，通過建立感染動物模型或采集病人樣本，對病原體和宿主之間的相互作用、機體免疫細胞和效應分子的活化和表達、免疫應答過程的信號傳導、免疫反應的分子調(diào)控等方面進行理論和應用基礎(chǔ)研究。

重點關(guān)注：1）炎癥與感染狀態(tài)下天然免疫細胞的活化與調(diào)控；2）蠕蟲感染的免疫致病機制。

1. Du, X., Ren, B., Li, C., Li, Q., Kan, S., Wang, X., Bai, W., Wu, C., Kassegne, K., Yan, H., Niu, X., Yan, M., Xu, W., Wassmer, S.C., Wang, J.#, Chen, G.#,Wang, Z.#, PRL2 regulates neutrophil extracellular trap formation which contributes to severe malaria and acute lung injury.Nature communications2024, 15(1).

2. Lei, Y.; Guo, X.; Luo, Y.; Niu, X.; Xi, Y.; Xiao, L.; He, D.; Bian, Y.; Zhang, Y.; Wang, L.; Peng, X.#;Wang, Z.#; Chen, G.#, Synovial microenvironment-influenced mast cells promote the progression of rheumatoid arthritis.Nature communications2024, 15 (1).

3. Li, Q.; Yue, T.; Du, X.; Tang, Z.; Cui, J.; Wang, W.; Xia, W.; Ren, B.; Kan, S.; Li, C.; Wu, C.; Niu, X.; Li, B.; Lin, K.; Luo, J.; Chen, G.#;Wang, Z.#, HSC70 mediated autophagic degradation of oxidized PRL2 is responsible for osteoclastogenesis and inflammatory bone destruction.Cell death and differentiation2023, 30 (3), 647-659.

4. Kan, S.; Li, Q.; Li, H. M.; Yao, Y. H.; Du, X. Y.; Wu, C. Y.; Chen, G. J.; Guo, X. K.; Qian, M. B.#;Wang, Z. J.#, Clonorchis sinensis infection modulates key cytokines for essential immune response impacted by sex.PLoS neglected tropical diseases2022, 16 (9), e0010726.

5. Wu, C.; Du, X.; Tang, L.; Wu, J.; Zhao, W.; Guo, X.; Liu, D.; Hu, W.; Helmby, H.; Chen, G.#;Wang, Z.#, Schistosoma japonicum SjE16.7 Protein Promotes Tumor Development via the Receptor for Advanced Glycation End Products (RAGE).Frontiers in immunology2020, 11, 1767.

6. Yin, C.; Wu, C.; Du, X.; Fang, Y.; Pu, J.; Wu, J.; Tang, L.; Zhao, W.; Weng, Y.; Guo, X.; Chen, G.#;Wang, Z.#, PRL2 Controls Phagocyte Bactericidal Activity by Sensing and Regulating ROS.Frontiers in immunology2018, 9, 2609.

7. Fayngerts, S. A.*;Wang, Z.*; Zamani, A.; Sun, H.; Boggs, A. E.; Porturas, T. P.; Xie, W.; Lin, M.; Cathopoulis, T.; Goldsmith, J. R.; Vourekas, A.; Chen, Y. H., Direction of leukocyte polarization and migration by the phosphoinositide-transfer protein TIPE2.Nature immunology2017, 18 (12), 1353-1360.

8. Wu, C.; Chen, Q.; Fang, Y.; Wu, J.; Han, Y.; Wang, Y.; Yang, Y.; Chu, M.; Feng, Y.; Tan, L.; Guo, X.; Hu, W.;Wang, Z.#, Schistosoma japonicum egg specific protein SjE16.7 recruits neutrophils and induces inflammatory hepatic granuloma initiation.PLoS neglected tropical diseases2014, 8 (2), e2703.

9.Wang, Z.*; Fayngerts, S.; Wang, P.; Sun, H.; Johnson, D. S.; Ruan, Q.; Guo, W.; Chen, Y. H., TIPE2 protein serves as a negative regulator of phagocytosis and oxidative burst during infection.Proceedings of the National Academy of Sciences of the United States of America2012, 109 (38), 15413-8.

10.Wang, Z.*; Qiu, J.*; Guo, T. B.; Liu, A.; Wang, Y.; Li, Y.; Zhang, J. Z., Anti-inflammatory properties and regulatory mechanism of a novel derivative of artemisinin in experimental autoimmune encephalomyelitis.Journal of immunology2007, 179 (9), 5958-65.

11.Wang, Z.*; Hong, J.*; Sun, W.; Xu, G.; Li, N.; Chen, X.; Liu, A.; Xu, L.; Sun, B.; Zhang, J. Z., Role of IFN-gamma in induction of Foxp3 and conversion of CD4+ CD25- T cells to CD4+ Tregs.The Journal of clinical investigation2006, 116 (9), 2434-41.