国产成人嫩模一区二区|超级黄色网页|兔子先生tz|麻豆文化传媒网站官网污|在线播放欧美日韩精品|爱豆影视传媒免费下载|蜜桃影像传媒av剧情|麻豆文化传媒APP最新iOS|陈可心倩女幽魂爱豆传媒|91国视频产,国产传媒播放,想看三级片,网红吃瓜黑料爆料网反差

李斌研究員2001年博士畢業(yè)于北京大學(xué)植物學(xué)專業(yè)，2001-2006年美國(guó)賓西法尼亞大學(xué)醫(yī)學(xué)院博士后,、2006-2009年高級(jí)研究助理；2009年受聘"中科院百人計(jì)劃",，任中科院上海巴斯德研究所課題組長(zhǎng),；2016年起任上海市免疫學(xué)研究所資深課題組長(zhǎng)、科研副所長(zhǎng),。

李斌研究員長(zhǎng)期從事免疫調(diào)節(jié)及重大免疫相關(guān)疾病如自身免疫病,、過敏性疾病及惡性腫瘤相關(guān)基礎(chǔ)及臨床應(yīng)用研究。近五年主持國(guó)家基金委免疫學(xué)杰青,、重點(diǎn),、面上、中波國(guó)際合作等基金,。T細(xì)胞免疫調(diào)控機(jī)制：FOXP3+T細(xì)胞具有重要的免疫抑制功能,，李斌課題組對(duì)于Treg細(xì)胞的穩(wěn)定性、FOXP3翻譯后修飾,、FOXP3蛋白復(fù)合體等調(diào)節(jié)機(jī)制進(jìn)行了系統(tǒng)的分析,。李斌課題組在國(guó)際學(xué)術(shù)刊物如J BIOL CHEM、J IMMUNOL cutting edge,、J VIROL,、PLOS Pathogens、PNAS,、NAT COMMS,、 GASTROENTEROLOGY、 IMMUNITY,、NAT IMMUNOL 等發(fā)表通訊及共同通訊作者論文60余篇,。 現(xiàn)任European Journal of Immunology全球12名執(zhí)行編委會(huì)成員之一。獲國(guó)家科技進(jìn)步二等獎(jiǎng)（2018）,、上海醫(yī)學(xué)科技獎(jiǎng),、中華醫(yī)學(xué)科技獎(jiǎng)等獎(jiǎng)勵(lì)。

近五年發(fā)表論文：

1. Guo Y#, Chen J#, Huang Y, Ke S, Xie F, Li D, Li B*, Lu H*. Increased infiltration of CD4+ IL-17A+ FOXP3+ T cells in Helicobacter?pylori-induced gastritis. Eur J Immunol. 2024 Mar;54(3):e2350662. doi: 10.1002/eji.202350662. Epub 2024 Feb 17. PMID: 38366919.

2. Liu X#, Zhang W#, Han Y#, Cheng H#, Liu Q#, Ke S, Zhu F, Lu Y, Dai X, Wang C, Huang G, Su B, Zou Q, Li H, Zhao W, Xiao L, Lu L, Tong X, Pan F*, Li H*, Li B*. FOXP3+ regulatory T cell perturbation mediated by the IFNγ-STAT1-IFITM3 feedback loop is essential for anti-tumor immunity. Nat Commun. 2024 Jan 2;15(1):122. doi: 10.1038/s41467-023-44391-9. PMID: 38167862; PMCID: PMC10761945.

3. Wang Z, Qin Z, Wang J, Xu X, Zhang M, Liang Y, Huang Y, Yu Z, Gong Y, Zhou L, Qiu Y, Ma M, Li D*, Li B*. Engineering extracellular vesicles with macrophage membrane fusion for ameliorating imiquimod-induced psoriatic skin inflammation. J Dermatolog Treat. 2023 Dec;34(1):2220445. doi: 10.1080/09546634.2023.2220445. Epub 2023 Jun 15. PMID: 38073229.

4. Guo Y, Xie F, Liu X, Ke S, Chen J, Zhao Y, Li N, Wang Z, Yi G, Shen Y, Li D, Zhu C, Zhang Z, Zhao G, Lu H*, Li B*, Zhao W*. Blockade of TNF-α/TNFR2 signalling suppresses colorectal cancer and enhances the efficacy of anti-PD1 immunotherapy by decreasing CCR8+ T regulatory cells. J Mol Cell Biol. 2023 Nov 3:mjad067. doi: 10.1093/jmcb/mjad067. Epub ahead of print. PMID: 37935468.

5. Yin H, Distler O, Shen L, Xu X, Yuan Y, Li R, Liu B, Li Q, Huang Q, Xie F, Zhang Z, Liang R, Dai X, Chen X, Li B*, Yan Q*, Lu L*. Endothelial Response to Type I Interferon Contributes to Vasculopathy and Fibrosis and Predicts Disease Progression of Systemic Sclerosis. Arthritis Rheumatol. 2024 Jan;76(1):78-91. doi: 10.1002/art.42662. PMID: 37488975.

6. Ke S#, Xie F#, Guo Y#, Chen J, Wang Z, Yu Y, Geng H, Xu D, Liu X, Xia X, Yu F, Zhu C, Zhang Z, Zhao G*, Li B*, Zhao W*. High-level of intratumoral GITR+ CD4 T cells associate with poor prognosis in gastric cancer. iScience. 2022 Nov 7;25(12):105529. doi: 10.1016/j.isci.2022.105529. PMID: 36419848; PMCID: PMC9676631.

7. Yang B, Deng B, Jiao XD, Qin BD, Lu Y, Zhang W, Guo Y, Chen S, Li D*, Li B*, Zang YS*. Low-dose anti-VEGFR2 therapy promotes anti-tumor immunity in lung adenocarcinoma by down-regulating the expression of layilin on tumor-infiltrating CD8+T cells. Cell Oncol (Dordr). 2022 Dec;45(6):1297-1309. doi: 10.1007/s13402-022-00718-0. Epub 2022 Oct 19. PMID: 36260222.

8. Jian Z, Han Y, Zhang W, Li C, Guo W, Feng X, Li B*, Li H*. Anti-tumor effects of dual PI3K-HDAC inhibitor CUDC-907 on activation of ROS-IRE1α-JNK-mediated cytotoxic autophagy in esophageal cancer. Cell Biosci. 2022 Aug 21;12(1):135. doi: 10.1186/s13578-022-00855-x. PMID: 35989326.

9. Deng B, Yang B, Chen J, Wang S, Zhang W, Guo Y, Han Y, Li H, Dang Y, Yuan Y, Dai X, Zang Y, Li Y*, Li B*. Gallic acid induces T-helper-1-like Treg cells and strengthens immune checkpoint blockade efficacy. J Immunother Cancer. 2022 Jul;10(7):e004037. doi: 10.1136/jitc-2021-004037. Erratum in: J Immunother Cancer. 2022 Oct;10(10): PMID: 35817479.

10. Liang R, Yuan Y, Bai Y, Liu X, Chen J, Jiang D, Meng D, Chen G, Li B*, Zhou L*, Guo W*. Neobavaisoflavone inhibits allergic inflammatory responses by suppressing mast cell activation. Int Immunopharmacol. 2022 Sep;110:108953. doi: 10.1016/j.intimp.2022.108953. Epub 2022 Jun 17. PMID: 35724607.

11. Qu G, Chen J, Li Y, Yuan Y, Liang R, Li B*. Current status and perspectives of regulatory T cell-based therapy. J Genet Genomics. 2022 Jul;49(7):599-611. doi: 10.1016/j.jgg.2022.05.005. Epub 2022 May 28. PMID: 35636740.

12. Liu Q, Zhu F, Liu X, Lu Y, Yao K, Tian N, Tong L, Figge DA, Wang X, Han Y, Li Y, Zhu Y, Hu L, Ji Y, Xu N, Li D, Gu X, Liang R, Gan G, Wu L, Zhang P, Xu T, Hu H, Hu Z, Xu H, Ye D, Yang H*, Li B*, Tong X*. Non-oxidative pentose phosphate pathway controls regulatory T cell function by integrating metabolism and epigenetics. Nat Metab. 2022 May;4(5):559-574. doi: 10.1038/s42255-022-00575-z. Epub 2022 May 23. PMID: 35606596.

13. Xu H, Zhu Z, Hu J, Sun J, Wo Y, Wang X, Zou H, Li B*, Zhang Y*. Downregulated cytotoxic CD8+ T-cell identifies with the NKG2A-soluble HLA-E axis as a predictive biomarker and potential therapeutic target in keloids. Cell Mol Immunol. 2022 Apr;19(4):527-539. doi: 10.1038/s41423-021-00834-1. Epub 2022 Jan 17. PMID: 35039632; PMCID: PMC8975835.

14. Bao L, Bo XC, Cao HW, Qian C, Wang Z*, Li B*. Engineered T cells and their therapeutic applications in autoimmune diseases. Zool Res. 2022 Mar 18;43(2):150-165. doi: 10.24272/j.issn.2095-8137.2021.363. PMID: 35008131; PMCID: PMC8920845.

15. Li Y, Lu Y, Lin SH, Li N, Han Y, Huang Q, Zhao Y, Xie F, Guo Y, Deng B, Tsun A, Du J, Li D, Sun J, Shi G, Zheng F, Su X, Duan S, Zheng SG, Wang G, Tong X*, Li B*. Insulin signaling establishes a developmental trajectory of adipose regulatory T cells. Nat Immunol. 2021 Sep;22(9):1175-1185. doi: 10.1038/s41590-021-01010-3. Epub 2021 Aug 24. PMID: 34429546.

16. Lu Y, Li Y, Liu Q, Tian N, Du P, Zhu F, Han Y, Liu X, Liu X, Peng X, Wang X, Wu Y, Tong L, Li Y, Zhu Y, Wu L, Zhang P, Xu Y, Chen H, Li B*, Tong X*. MondoA-Thioredoxin-Interacting Protein Axis Maintains Regulatory T-Cell Identity and Function in Colorectal Cancer Microenvironment. Gastroenterology. 2021 Aug;161(2):575-591.e16. doi: 10.1053/j.gastro.2021.04.041. Epub 2021 Apr 24. PMID: 33901495.

17. Liu Y, Du J, Liu X, Wang L, Han Y, Huang C, Liang R, Zheng F, Shi G*, Li B*. MG149 inhibits histone acetyltransferase KAT8-mediated IL-33 acetylation to alleviate allergic airway inflammation and airway hyperresponsiveness. Signal Transduct Target Ther. 2021 Sep 8;6(1):321. doi: 10.1038/s41392-021-00667-4. PMID: 34493712; PMCID: PMC8423820.

18. Zhang W, Liu X, Zhu Y, Liu X, Gu Y, Dai X*, Li B*. Transcriptional and posttranslational regulation of Th17/Treg balance in health and disease. Eur J Immunol. 2021 Jul 28. doi: 10.1002/eji.202048794. Epub ahead of print. PMID: 34322865.

19. Zhai T, Wang C, Xu Y, Huang W, Yuan Z, Wang T, Dai S, Peng S, Pang T, Jiang W, Huang Y, Zou Y, Xu Y, Sun J, Gong X, Zhang J, Tsun A*, Li B* & Miao X*. Generation of a safe and efficacious llama single-domain antibody fragment (vHH) targeting the membrane-proximal region of 4-1BB for engineering therapeutic bispecific antibodies for cancer. J Immunother Cancer. 2021 Jun;9(6):e002131. doi: 10.1136/jitc-2020-002131. PMID: 34172514; PMCID: PMC8237747.

20. Lin Y, Zhang D, Li Y, Li Y, Li B*, Du M*. Decidual NR2F2-Expressing CD4+ T Cells Promote TH2 Transcriptional Program During Early Pregnancy. Front Immunol. 2021 May 18;12:670777. doi: 10.3389/fimmu.2021.670777. PMID: 34084171; PMCID: PMC8168462.

21. Deng B, Zhang W, Zhu Y, Li Y, Li D, Li B*. FOXP3+ regulatory T cells and age-related diseases. FEBS J. 2021 Feb 2. doi: 10.1111/febs.15743. Epub ahead of print. PMID: 33529458.

22. Hou X, Zhu F, Ni Y, Chen T, Du J, Liu X, Han Y, Liu Y, Du W, Li Y, Wang X, Li D, Liang R, Li B*, Shi G*. USP4 is pathogenic in allergic airway inflammation by inhibiting regulatory T cell response. Life Sci. 2021 Sep 15;281:119720. doi: 10.1016/j.lfs.2021.119720. Epub 2021 Jun 16. PMID: 34144056.

23. Liang CL, Lu W, Qiu F, Li D, Liu H, Zheng F, Zhang Q, Chen Y, Lu C, Li B, Dai Z. Paeoniflorin ameliorates murine lupus nephritis by increasing CD4+Foxp3+ Treg cells via enhancing mTNFα-TNFR2 pathway. Biochem Pharmacol. 2021 Mar;185:114434.

24. Li H, Yu X, Shi B, Zhang K, Yuan L, Liu X, Wang P, Lv J, Meng G, Xuan Q, Wu W, Li B, Peng X, Qin X, Liu W, Zhong L, Peng Z. Reduced pannexin 1-IL-33 axis function in donor livers increases risk of MRSA infection in liver transplant recipients. Sci Transl Med. 2021 Aug 11;13(606):eaaz6169. doi: 10.1126/scitranslmed.aaz6169. PMID: 34380770.

25. Zeng F, Chen H, Chen L, Mao J, Cai S, Xiao Y, Li J, Shi J, Li B, Xu Y, Tan Z, Gong F, Li B, Qian Y, Dong L, Zheng F. An Autocrine Circuit of IL-33 in Keratinocytes Is Involved in the Progression of Psoriasis. J Invest Dermatol. 2021 Mar;141(3):596-606.e7.

26. Yang M, Huang Q, Li C, Jiang Z, Sun J, Wang Z, Liang R, Li D*, Li B*, Zhao H*. TOX Acts as a Tumor Suppressor by Inhibiting mTOR Signaling in Colorectal Cancer. Front Immunol. 2021 Apr 9;12:647540. doi: 10.3389/fimmu.2021.647540.

27. Wang X, Cheng H, Shen Y, Li B*. Metabolic Choice Tunes Foxp3+ Regulatory T Cell Function. Adv Exp Med Biol. 2021;1278:81-94.

28. Liu X, Meng X, Peng X, Yao Q, Zhu F, Ding Z, Sun H, Liu X, Li D, Lu Y, Tang H, Li B*, Peng Z*. Impaired AGO2/miR-185-3p/NRP1 axis promotes colorectal cancer metastasis. Cell Death Dis. 2021 Apr 12;12(4):390.

29. Qian Y, Zhu Y, Li Y*, Li B*. Legend of the Sentinels: Development of Lung Resident Memory T Cells and Their Roles in Diseases. Front Immunol. 2021 Feb 2;11:624411.

30. Zhang Y, Xiong DH, Li Y, Xu G, Zhang B, Liu Y, Zhang S, Huang Q, Chen S, Zeng F, Guo J, Li B, Qin Z, Zhang Z. Schistosoma japonicum Infection in Treg-Specific USP21 Knockout Mice. J Immunol Res. 2021 Feb 9;2021:6613162. doi: 10.1155/2021/6613162. PMID: 33628844; PMCID: PMC7886505.

31. Zhu Y, Qian Y, Li Z, Li Y*, Li B*. Neoantigen-reactive T cell: An emerging role in adoptive cellular immunotherapy. MedComm (2020). 2021 Apr 23;2(2):207-220. doi: 10.1002/mco2.41. PMID: 34766142; PMCID: PMC8491202.

32. Liu X, Tian N, Huang Q, Xu Z, Cheng H, Liu X, Li D, Liang R, Li B*, Dai X*. hnRNPA1 enhances FOXP3 stability to promote the differentiation and functions of regulatory T cells. FEBS Lett. 2021 Jul;595(14):1962-1974. doi: 10.1002/1873-3468.14142. Epub 2021 Jun 22. PMID: 34080184.

33. Qian SJ, Huang QR, Chen RY, Mo JJ, Zhou LY, Zhao Y, Li B*, Lai HC*. Single-Cell RNA Sequencing Identifies New Inflammation-Promoting Cell Subsets in Asian Patients With Chronic Periodontitis. Front Immunol. 2021 Sep 8;12:711337. doi: 10.3389/fimmu.2021.711337. PMID: 34566966; PMCID: PMC8455889.

34. Luo L, Liang W, Pang J, Xu G, Chen Y, Guo X, Wang X, Zhao Y, Lai Y, Liu Y, Li B, Su B, Zhang S, Baniyash M, Shen L, Chen L, Ling Y, Wang Y, Liang Q, Lu H, Zhang Z, Wang F. Dynamics of TCR repertoire and T cell function in COVID-19 convalescent individuals. Cell Discov. 2021 Sep 28;7(1):89. doi: 10.1038/s41421-021-00321-x. PMID: 34580278; PMCID: PMC8476510.

35. Liu Y, Huang Q, Du J, Huang C, Li D, Dai X, Liang R, Li B*, Shi G*. Comparative analysis of global transcriptome, proteome and acetylome in house dust mite-induced murine allergic asthma model. Clin Transl Med. 2021 Nov;11(11):e590. doi: 10.1002/ctm2.590. PMID: 34841691; PMCID: PMC8571946.

36. Cheng H, Wang L, Yang B, Li D, Wang X, Liu X, Tian N, Huang Q, Feng R, Wang Z, Liang R, Dai SM, Lv L, Wu J*, Zang YS*, Li B*. Cutting Edge: Inhibition of Glycogen Synthase Kinase 3 Activity Induces the Generation and Enhanced Suppressive Function of Human IL-10+ FOXP3+-Induced Regulatory T Cells. J Immunol. 2020 Sep 15;205(6):1497-1502. doi: 10.4049/jimmunol.2000136. Epub 2020 Aug 19. PMID: 32817370; PMCID: PMC7477744.

37. Yang J, Wei P, Barbi J, Huang Q, Yang E, Bai Y, Nie J, Gao Y, Tao J, Lu Y, Xie C, Hou X, Ren J, Wu X, Meng J, Zhang Y, Fu J, Kou W, Gao Y, Chen Z, Liang R, Tsun A, Li D, Guo W, Zhang S, Zheng SG, Niu J, Galardy P, Tong X, Shi G, Li H*, Pan F*, Li B*. The deubiquitinase USP44 promotes Treg function during inflammation by preventing FOXP3 degradation. EMBO Rep. 2020 Sep 3;21(9):e50308. doi: 10.15252/embr.202050308. Epub 2020 Jul 9. PMID: 32644293; PMCID: PMC7507386.

38. Gu W, Ge R, Zhu F, Li D, Liang R, Ge J, Wang Y, Li B, Qiu J. PARP-1 inhibitor-AG14361 suppresses acute allograft rejection via stabilizing CD4+FoxP3+ regulatory T cells. Pathol Res Pract. 2020 Aug;216(8):153021. doi: 10.1016/j.prp.2020.153021. Epub 2020 May 21. PMID: 32703489.

39. Yang M, Wang A, Li C, Sun J, Yi G, Cheng H, Liu X, Wang Z, Zhou Y, Yao G, Wang S, Liang R, Li B*, Li D*, Zhao H*. Methylation-Induced Silencing of ALDH2 Facilitates Lung Adenocarcinoma Bone Metastasis by Activating the MAPK Pathway. Front Oncol. 2020 Jul 30;10:1141. doi: 10.3389/fonc.2020.01141. PMID: 32850324; PMCID: PMC7406638.

40. Tian N, Liu Q, Li Y, Tong L, Lu Y, Zhu Y, Zhang P, Chen H, Hu L, Meng J, Feng M, Li M, Zheng L, Li B, Xu T, Wu L, Tong X. Transketolase Deficiency in Adipose Tissues Protects Mice From Diet-Induced Obesity by Promoting Lipolysis. Diabetes. 2020 Jul;69(7):1355-1367. doi: 10.2337/db19-1087. Epub 2020 Apr 15. PMID: 32295803.

41. Wang A, Yang M, Liang R, Zhu F, Zhu F, Liu X, Han Y, Lin R, Wang X, Li D, Li H, Yuan X, Zhao H*, Li B*. Mouse Double Minute 2 Homolog-Mediated Ubiquitination Facilitates Forkhead Box P3 Stability and Positively Modulates Human Regulatory T Cell Function. Front Immunol. 2020 Jun 19;11:1087. doi: 10.3389/fimmu.2020.01087. PMID: 32636834; PMCID: PMC7318079.

42. Gang Yi, Yi Zhao, Feng Xie, Fuxiang Zhu, Ziyun Wan, Xiu Qiu, Huanming Yang, Jian Wang, Bing Su, Lei Chen, Wei Zhang, Yong Hou, Xun Xu, Yinyan He, Andy Tsun, Xiao Liu, Bin Li*. Single-cell RNA-seq unveils critical regulators of human FOXP3+ regulatory T cell stability. Science Bulletin Volume 65, Issue 13, 15 July 2020, Pages 1114-1124.

43. Bai F, Zhang P, Fu Y, Chen H, Zhang M, Huang Q, Li D*, Li B*, Wu K*. Targeting ANXA1 abrogates Treg-mediated immune suppression in triple-negative breast cancer. J Immunother Cancer. 2020 Apr;8(1):e000169. doi: 10.1136/jitc-2019-000169. PMID: 32300050; PMCID: PMC7204868.

44. Wang X, Yang Y, Ren D, Xia Y, He W, Wu Q, Zhang J, Liu M, Du Y, Ren C, Li B, Shen J, Zhang Y. JQ1, a bromodomain inhibitor, suppresses Th17 effectors by blocking p300-mediated acetylation of RORγt. Br J Pharmacol. 2020 Jul;177(13):2959-2973. doi: 10.1111/bph.15023. Epub 2020 Mar 23. PMID: 32060899; PMCID: PMC7280011.

45. Zhao J, Zhang Y, Liu XS, Zhu FM, Xie F, Jiang CY, Zhang ZY, Gao YL, Wang YC, Li B*, Xia SJ*, Han BM*. RNA-binding protein Musashi2 stabilizing androgen receptor drives prostate cancer progression. Cancer Sci. 2020 Feb;111(2):369-382. doi: 10.1111/cas.14280. Epub 2020 Jan 4. PMID: 31833612; PMCID: PMC7004550.

46. Huang Q, Liu X, Zhang Y, Huang J, Li D*, Li B*. Molecular feature and therapeutic perspectives of immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome. J Genet Genomics. 2020 Jan 20;47(1):17-26. doi: 10.1016/j.jgg.2019.11.011. Epub 2020 Jan 24. PMID: 32081609.

47. Huang J, Wang S, Jia Y, Zhang Y, Dai X*, Li B*. Targeting FOXP3 complex ensemble in drug discovery. Adv Protein Chem Struct Biol. 2020;121:143-168. doi: 10.1016/bs.apcsb.2019.11.010. Epub 2020 Jan 7. PMID: 32312420.

48. Wang A, Zhu F, Liang R, Li D, Li B*. Regulation of T cell differentiation and function by ubiquitin-specific proteases. Cell Immunol. 2019 Jun;340:103922. doi: 10.1016/j.cellimm.2019.103922. Epub 2019 May 3. PMID: 31078284.

49. Zhao Y, Li X, Zhao W, Wang J, Yu J, Wan Z, Gao K, Yi G, Wang X, Fan B, Wu Q, Chen B, Xie F, Wu J, Zhang W, Chen F, Yang H, Wang J, Xu X, Li B, Liu S, Hou Y, Liu X. Single-cell transcriptomic landscape of nucleated cells in umbilical cord blood. Gigascience. 2019 May 1;8(5):giz047. doi: 10.1093/gigascience/giz047. PMID: 31049560; PMCID: PMC6497034.

50. Ren J, Han L, Tang J, Liu Y, Deng X, Liu Q, Hao P, Feng X, Li B, Hu H, Wang H. Foxp1 is critical for the maintenance of regulatory T-cell homeostasis and suppressive function. PLoS Biol. 2019 May 24;17(5):e3000270. doi: 10.1371/journal.pbio.3000270. PMID: 31125332; PMCID: PMC6534289.

51. Nagai Y, Ji MQ, Zhu F, Xiao Y, Tanaka Y, Kambayashi T, Fujimoto S, Goldberg MM, Zhang H, Li B, Ohtani T, Greene MI. PRMT5 Associates With the FOXP3 Homomer and When Disabled Enhances Targeted p185erbB2/neu Tumor Immunotherapy. Front Immunol. 2019 Feb 8;10:174. doi: 10.3389/fimmu.2019.00174. PMID: 30800128; PMCID: PMC6375878.

52. Ni X, Kou W, Gu J, Wei P, Wu X, Peng H, Tao J, Yan W, Yang X, Lebid A, Park BV, Chen Z, Tian Y, Fu J, Newman S, Wang X, Shen H, Li B, Blazar BR, Wang X, Barbi J, Pan F, Lu L. TRAF6 directs FOXP3 localization and facilitates regulatory T-cell function through K63-linked ubiquitination. EMBO J. 2019 May 2;38(9):e99766. doi: 10.15252/embj.201899766. Epub 2019 Mar 18. PMID: 30886050; PMCID: PMC6484404.