課題組長(zhǎng)簡(jiǎn)介
Florent Ginhoux,上海交通大學(xué)醫(yī)學(xué)院上海市免疫學(xué)研究所客座教授,,新加坡免疫學(xué)聯(lián)網(wǎng)(Singapore Immunology Network)高級(jí)研究員,,新加坡免疫學(xué)會(huì)副主席。主要從事樹突狀細(xì)胞,、單核細(xì)胞和巨噬細(xì)胞發(fā)育研究,,是該領(lǐng)域頂尖的科學(xué)家之一。近三年內(nèi)在Nature,、Science,、Cell、Nature Immunology,、Immunity等雜志發(fā)表大量研究論文,。
Florent Ginhoux在上海市免疫學(xué)研究所的實(shí)驗(yàn)室主要從事單核-巨噬細(xì)胞的發(fā)育和功能研究,研究工作發(fā)表于2019年Cell雜志,。單核-巨噬細(xì)胞是腫瘤微環(huán)境中數(shù)量多的免疫細(xì)胞群體,,和微環(huán)境中其他細(xì)胞類群具有廣泛的交流,在調(diào)控腫瘤免疫微環(huán)境中起到核心作用,,是有價(jià)值的腫瘤免疫治療靶標(biāo),。靶向這些細(xì)胞需要對(duì)其發(fā)育過程和控制其穩(wěn)態(tài)的機(jī)制有深入的了解,我們將從發(fā)育學(xué)角度出發(fā),,使用能夠?qū)魏思?xì)胞進(jìn)行示蹤的動(dòng)物模型來深入研究這些科學(xué)問題,,以期開發(fā)靶向這些細(xì)胞的腫瘤治療方案。我們希望有志于此的青年博士加入我們,,共同努力,!
相關(guān)連接
Florent Ginhoux課題組 :DetailMemberInfo.php?pid=6&cid=114&num=114&id=19
https://www.a-star.edu.sg/docs/librariesprovider26/publication/publications_florent-ginhoux-(updated-19nov2020).pdf
崗位要求:
1. 獲得(或即將獲得)免疫學(xué)、分子生物學(xué),、細(xì)胞生物學(xué),、生物化學(xué)或醫(yī)學(xué)相關(guān)專業(yè)博士學(xué)位;入站時(shí)獲得博士學(xué)位的時(shí)間不超過三年,,年齡35周歲以下,。
2. 具有良好的英語(yǔ)交流和寫作能力,;
3. 科學(xué)態(tài)度嚴(yán)謹(jǐn),思維活躍,,有好奇心,,具有較強(qiáng)的工作責(zé)任心和團(tuán)隊(duì)協(xié)作精神;
崗位待遇:
1. 課題組將為博后提供大量接觸該領(lǐng)域頂尖科學(xué)家的機(jī)會(huì),;提供良好的個(gè)人發(fā)展平臺(tái),,提供出國(guó)學(xué)習(xí)和參加國(guó)際會(huì)議等訪問交流機(jī)會(huì)
2. 提供具有競(jìng)爭(zhēng)性的待遇和相關(guān)福利。具體按照上海交通大學(xué)醫(yī)學(xué)院和上海市免疫學(xué)研究所相關(guān)標(biāo)準(zhǔn)執(zhí)行,。
申請(qǐng)方式:請(qǐng)將個(gè)人簡(jiǎn)歷(英文)發(fā)至[email protected],。郵件標(biāo)題請(qǐng)注明應(yīng)聘博士后。應(yīng)聘材料將予以保密,。
Postdoc advertisement
Florent Ginhoux's lab at the Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine is recruiting 2 postdocs (PhD or MD/PhD) with an immunology background and expertise in the field of myeloid cells and tumor immunology.
Please visit our lab website for details: (DetailMemberInfo.php?pid=6&cid=114&num=114&id=19)
About the PI
Florent Ginhoux is a Senior Principal Investigator at the Singapore Immunology Network (SIgN), A*STAR and an Adjunct Professor at the Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine. He is one of the top scientists in the field of myeloid cells, and has published works in Nature, Science, Cell, Immunity and Nature Immunology as a corresponding author (full list of publications: https://www.a-star.edu.sg/docs/librariesprovider26/publication/publications_florent-ginhoux-(updated-19nov2020).pdf). Research in the lab focuses on understanding the ontogeny and function of myeloid cells in both humans and mice, as well as the function of these cells in tumor immunology. In 2019, we generated a monocyte fate mapping model that could distinguish macrophages with different developmental origins (embryonic or monocyte-derived) and published our findings in Cell, paving the way to investigating the function of macrophages with different origins in tumors. Myeloid cells are the most abundant populations in the tumor microenvironment and are key mediators of cellular cross-talk, and are thereby valuable therapeutic targets. Potential intervention strategies aiming at manipulation of these cells will require in-depth insights of their origins and the mechanisms that govern their homeostasis. Through the use of Ms4a3 monocyte fate mapping models, we can begin to have a clearer understanding of these questions.
Postdoc positions
The Ginhoux lab is looking for highly motivated and talented scientists to address the fundamental questions in the field of myeloid cells. Candidates with Ph.D., M.D., degrees that interested in understanding the ontogeny and function of myeloid cells in tumor biology are welcome to apply. Please email your CV, a brief description of your previous work and your future research interests to [email protected], if interested.
Contact Information:
Tel: 021-63846590-776733
email: [email protected]