Quan Zheng
Assistant Researcher
Ph.D. in Cell Biology, Shanghai Jiao Tong University School of Medicine
B.S. in Biotechnology, Huazhong Agricultural University
Email: [email protected]
Office: Room 403, East 5 building
Postdoctor:
01/2017 – 01/2020, Shanghai Jiao Tong University School of Medicine, preclinical medicine, postdoctor.
Grants:
1) China Postdoctoral Science Foundation, 2017M611583, 07/2017-07/2019
2) National Natural Science Foundation of China, 81902673, 01/2020-12/2022
Publication：
1. Guo H, Xu J, Zheng Q, et al.. NRF2 SUMOylation promotes de novo serine synthesis and maintains HCC tumorigenesis. Cancer Lett. 2019 Dec 1;466:39-48. (IF=6.508)
2. Liang Q, Zheng Q, et al.. SENP2 Suppresses Necdin Expression to Promote Brown Adipocyte Differentiation. Cell Rep. 2019 Aug 20;28(8):2004-2011. (IF=7.815)
3. Wang T, Cao Y, Zheng Q, et al.. SENP1-Sirt3 Signaling Controls Mitochondrial Protein Acetylation and Metabolism. Mol Cell. 2019 Aug 22;75(4):823-834. (IF=14.548)
4. Zheng Q, Cao Y, et al.. Senp2 regulates adipose lipid storage by de-SUMOylation of Setdb1.J Mol Cell Biol. 2018 Jun 1;10(3):258-266. (IF=5.595)
Patents:
1) Identification and application of compounds in regulating SENP1 phosphorylation and SIRT3 SUMOyaltion, 201711349811.2;
2) Biomarkers for diagnosis, treatment and prognosis of luminal or HER2-positive breast cancer, 201910420781.2;
3) Application of autocrine VEGFB in T cell metabolism, function and tumor immunotherapy, 201910613188.X;
