個人簡介 受教育經(jīng)歷 1999.9-2004.7 四川大學(xué)華西醫(yī)學(xué)中心病理生理學(xué)專業(yè) 碩-博士研究生 1990.9-1995.7 北京大學(xué)醫(yī)學(xué)部預(yù)防醫(yī)學(xué)專業(yè) 醫(yī)學(xué)學(xué)士 研究工作經(jīng)歷 2006.7-至今 上海交通大學(xué)醫(yī)學(xué)院 講師/副教授 2009.5-2011.4 美國德州大學(xué)泰勒醫(yī)學(xué)研究中心/呼吸道感染性疾病防治中心 博士后 2004.9-2006.7 上海交通大學(xué)醫(yī)學(xué)院上海市免疫學(xué)研究所 博士后 1999.9-2004.7 四川大學(xué)華西基礎(chǔ)醫(yī)學(xué)院病理學(xué)與病理生理學(xué) 碩/博士研究生 1995.7-1999.8 廣西北海市疾病預(yù)防控制中心流行病科 衛(wèi)生醫(yī)師 主要研究方向 環(huán)境污染物暴露健康危害及其機(jī)制研究 主要研究課題（近五年15項(xiàng)之內(nèi)） 1．“基于人胚胎干細(xì)胞的環(huán)境內(nèi)分泌干擾物低劑量暴露胚胎毒性評價(jià)模型的研究” 2. “PM2.5及其組分的神經(jīng)發(fā)育毒性及機(jī)制研究” 3. “十溴聯(lián)苯醚(BDE-209)長期暴露的免疫毒性效應(yīng)及其機(jī)制研究” 4. “環(huán)境內(nèi)分泌干擾物暴露及環(huán)境基因交互作用與女性生殖功能的關(guān)聯(lián)” 5. “結(jié)核分枝桿菌分泌蛋白HtdY誘導(dǎo)樹突狀細(xì)胞成熟的信號通路及Th1/Th2極化研究” 6. “CD200R對肺泡巨噬細(xì)胞凋亡的影響及其在流感病毒感染早期的作用研究” 7. “TIPE2-Rac信號通路在感染免疫中的作用與機(jī)理研究” 主要研究成果(論文論著等,近五年，限20篇之內(nèi))
Wei H, Feng Y, Liang F, Cheng W, Wu X, Zhou R, Wang Y. Role of oxidative stress and DNA hydroxymethylation in the neurotoxicity of fine particulate matter. Toxicology, 2017.01.30, 380：94~103 Wei, Hongying, Liang, Fan, Meng, Ge, Nie, Zhiqing, Zhou, Ren, Cheng, Wei, Wu, Xiaomeng, Feng, Yan*, Wang, Yan*. Redox/methylation mediated abnormal DNA methylation as regulators of ambient fine particulate matter-induced neurodevelopment related impairment in human neuronal cells. Sci Rep, 2016.9.14, 6: 33402~33402 Feng, Yan#, Zeng, Weihong#, Wang, Ying Shen, Hao, Wang, Yan. Long-term exposure to high levels of decabrominated diphenyl ether inhibits CD4 T-cell functions in C57BL/6 mice. J Appl Toxicol, 2016.9.01, 36(9): 1112~1119 Cheng, Wei, Zhou, Ren, Liang, Fan, Wei, Hongying, Feng, Yan, Wang, Yan. Application of Mouse Embryonic Stem Cell Test to Detect Gender-Specific Effect of Chemicals: A Supplementary Tool for Embryotoxicity Prediction. Chem Res Toxicol, 2016.9.19, 29(9): 1519~1533 Cheng, Wei, Zhou, Ren, Feng, Yan*, Wang, Yan*. Mainstream smoke and sidestream smoke affect the cardiac differentiation of mouse embryonic stem cells discriminately. Toxicology. 2016.5.16, 357-358:1~10 Meng, Ge, Nie, Zhiqing, Feng, Yan, Wu, Xiaomeng, Yin, Yong, Wang, Yan. Typical halogenated persistent organic pollutants in indoor dust and the associations with childhood asthma in Shanghai, China.,，Environ Pollut,，2016.4.01，211：389~398 Meng, Ge, Feng, Yan, Nie, Zhiqing, Wu, Xiaomeng, Wei, Hongying, Wu, Shaowei, Yin, Yong, Wang, Yan. Internal exposure levels of typical POPs and their associations with childhood asthma in Shanghai, China. Environ Res, 2016.4.01,，146: 125~135 Feng, Yan#, Hu, Qingliang#, Meng, Ge, Wu, Xiaomeng，Zeng, Weihong, Zhang, Xing, Yu, Yingxin, Wang, Yan. Simulating long-term occupational exposure to decabrominated diphenyl ether using C57BL/6 mice: Biodistribution and pathology. Chemosphere, 2015.2.13,，128C: 118~124 Zeng W, Wang Y, Liu Z, Khanniche A, Hu Q, Yan Feng, Ye W, Yang J, Wang S, Zhou L, Shen H, Wang Y. Long-term exposure to decabrominated diphenyl ether impairs CD8 T-cell function in adult mice,，Cell Mol Immunol, 2014.7.1, 11(4): 367~376 Guo, Jianfei#, Feng, Yan#, Barnes, Peter, Huang, Fang-Fang, Idell, Steven，Su, Dong-Ming, Shams, Homayoun. Deletion of FoxN1 in the thymic medullary epithelium reduces peripheral T cell responses to infection and mimics changes of aging. PLos One, 2012.01.01, 7(4): e34681~e34681 Feng, Yan#, Kong, Ying#, Barnes, Peter F, Huang, Fang-Fang, Klucar, Peter, Wang, Xisheng, Samten, Buka, Sengupta, Mayami, Machona, Bruce, Donis, Ruben Tvinnereim, Amy R, Shams, Homayoun. Exposure to cigarette smoke inhibits the pulmonary T-cell response to influenza virus and Mycobacterium tuberculosis. Infection and Immunity, 2011.1.01, 79(1): 229~237 Huang, Fang-Fang, Barnes, Peter F, Feng, Yan, Donis, Ruben, Chroneos, Zissis C, Idell, Steven, Allen, Timothy, Perez, Daniel R, Whitsett, Jeffrey A, Dunussi-Joannopoulos, Kyri, Shams, Homayoun. GM-CSF in the lung protects against lethal influenza infection. Am J Respir Crit Care Med, 2011.7.15, 184(2): 259~268 Wu, CY#, Feng, Y#, Qian, GC, Wu, JH, Luo, J, Wang, Y, Chen, GJ, Guo, XK, Wang, ZJ. alpha-Galactosylceramide protects mice from lethal Coxsackievirus B3 infection and subsequent myocarditis. Clin Exp Immunol,，2010.10.01, 162(1): 178~187 Shi, Yufeng, Feng, Yan, Kang, Jiuhong, Liu, Chang, Li, Zhenxin, Li, Dangsheng, Cao, Wei, Qiu, Ju, Guo, Zhengliang, Bi, Enguang, Zang, Lei, Lu, Chuanzhen, Zhang, Jingwu Z, Pei, Gang. Critical regulation of CD4+ T cell survival and autoimmunity by beta-arrestin 1. Nat Immunol, 2007.8.01, 8(8): 817~824 教學(xué)工作 1,、“衛(wèi)生微生物學(xué)”課程的教學(xué) 2、“預(yù)防醫(yī)學(xué)”課程的教學(xué) 3,、“環(huán)境與健康”課程的教學(xué) |
