個(gè)人簡(jiǎn)介：
2017年畢業(yè)于復(fù)旦大學(xué)并獲得生物信息學(xué)博士學(xué)位,，曾在碩博連讀期間聯(lián)合培養(yǎng)于美國(guó)德克薩斯大學(xué)生物統(tǒng)計(jì)系,；2017年進(jìn)入上海交通大學(xué)醫(yī)學(xué)院公共衛(wèi)生學(xué)院工作,；2019-2020年于喬治亞大學(xué)生物信息中心開展訪問研究工作,。主要從事精準(zhǔn)醫(yī)學(xué)與公共健康相關(guān)研究,?；谌祟愡z傳學(xué),、基因組學(xué)及臨床表型數(shù)據(jù),，深入研究復(fù)雜疾病發(fā)生發(fā)展過(guò)程中的遺傳因素與環(huán)境因素的交互作用，構(gòu)建廣泛應(yīng)用的健康指數(shù)標(biāo)準(zhǔn)體系并建立健康標(biāo)準(zhǔn)數(shù)據(jù)庫(kù),，系統(tǒng)性地探討和發(fā)展用于復(fù)雜疾病預(yù)防的新技術(shù)和新方法,。以第一承擔(dān)人獲得國(guó)家自然科學(xué)基金一項(xiàng)，校級(jí)課題兩項(xiàng),，參與國(guó)家級(jí)和省部級(jí)多項(xiàng)課題研究,。研究成果發(fā)表在Molecular Biology and Evolution, Genomics Proteomics and Bioinformatics, Brain Behaviour and Immunity等國(guó)際一流雜志，累積發(fā)表SCI論文20余篇,。學(xué)術(shù)兼職為國(guó)際MAQC學(xué)會(huì)(組學(xué)大數(shù)據(jù)質(zhì)量控制學(xué)會(huì))會(huì)員,、美國(guó)人類遺傳學(xué)會(huì)會(huì)員(ASHG)、分子生物與進(jìn)化學(xué)協(xié)會(huì)(SMBE)和中國(guó)生物工程學(xué)會(huì)暨全國(guó)計(jì)算生物學(xué)和生物信息學(xué)學(xué)會(huì)會(huì)員,。擔(dān)任Briefing in Bioinformatics,、Genome Biology and Evolution、Current Drug Metabolism等多家SCI雜志審稿人,。
研究方向：
基因組學(xué)與精準(zhǔn)公共衛(wèi)生：利用基因組學(xué)和其他大數(shù)據(jù)和人工智能來(lái)預(yù)測(cè)疾病風(fēng)險(xiǎn)和與結(jié)果,，用于改善群體健康；
基于多組學(xué)數(shù)據(jù)整合的復(fù)雜疾病靶標(biāo)預(yù)測(cè)研究,；
主要科研項(xiàng)目：
國(guó)家自然科學(xué)基金青年項(xiàng)目,，31801049，課題負(fù)責(zé)人
上海交通大學(xué)醫(yī)工交叉基金,，YG2017QN69,，課題負(fù)責(zé)人
上海交通大學(xué)青年師資科研能力海外培訓(xùn)項(xiàng)目，KJ3-0221-18-4403,，課題負(fù)責(zé)人
上海交通大學(xué)新進(jìn)青年教師啟動(dòng)計(jì)劃,，課題負(fù)責(zé)人
近五年代表性成果：
Zhou, J., Liu, C., Sun, Y., Huang, W. and Ye, K., 2020. Cognitive disorders associated with hospitalization of COVID-19: Results from an observational cohort study. Brain, Behavior, and Immunity. Jan; 91:383-392.
Zhou J, Sun Y, Huang W, Ye K. 2021, Altered blood cell traits underlie a major genetic locus of severe COVID-19. The Journals of Gerontology: Series A, glab035
Zhou, J., Liu, C., Francis, M., Sun, Y., Ryu, M.S., Grider, A. and Ye, K., 2020. The Causal Effects of Blood Iron and Copper on Lipid Metabolism Diseases: Evidence from Phenome-Wide Mendelian Randomization Study. Nutrients, 12(10), p.3174.
Zhou, J., Liu, C., Sun, Y., Francis, M., Ryu, M.S., Grider, A. and Ye, K., Genetically predicted circulating levels of copper and zinc are associated with osteoarthritis but not with rheumatoid arthritis. Osteoarthritis and Cartilage. 2021 Feb 25;S1063-4584(21)00620-8.
Sun Y, Zhou J, Ye K. White Blood Cells and Severe COVID-19: A Mendelian Randomization Study. J Pers Med. 2021 Mar 12;11(3):195.
Zhou J, Liu C, Francis M, Sun Y, Ryu M, Grider A, Ye K. Shared and Unique Clinical Effects of Five Circulating Minerals: A Comparative Phenome-Wide Mendelian Randomization Study. Current Developments in Nutrition, 01 Jun 2021, 5(Suppl2):1112-1112
Francis M, Li C, Sun Y, Zhou J, Li X, Brenna JT, Ye K. Genome-wide association study of fish oil supplementation on lipid traits in 81,246 individuals reveals new gene-diet interaction loci. PLoS Genet. 2021 Mar 24;17(3):e1009431.
Wang, Z., Zhou, J., Marshall, B., Rekaya, R., Ye, K. and Liu, H.X., 2020. SARS-CoV-2 receptor ACE2 is enriched in a subpopulation of mouse tongue epithelial cells in nongustatory papillae but not in taste buds or embryonic oral epithelium. ACS pharmacology & translational science, 3(4), pp.749-758.
Li L, Liu D, Liu A, Li J, Wang H*, Zhou J*. 2020, Genomic survey of tyrosine kinases repertoire in Electrophorus electricus with an emphasis on evolutionary conservation and diversification. Evolutionary Bioinformatics. DOI: 10.1177/1176934320922519
Liu A, He F, Shen L, Liu R, Wang Z, Zhou J*. Convergent degeneration of olfactory receptor gene repertoires in marine mammals. BMC Genomics, 2019, 20(1), 977.
Zhang Y, Song J, Shi Q, Song X, Shen L, Zhou J*, Shao J*. The prognostic signature of the somatic mutations in Ewing sarcoma: from a network view. Japanese Journal of Clinical Oncology. 2019, 49(7):604-13.
Zhou J, Liu D, Sa Z, Huang W, Zou Y*, Gu X*. Effective estimation of the minimum number of amino acid residues required for functional divergence between duplicate genes. Molecular Phylogenetics and Evolution. 2017,113:126-138.
Sa Z#, Zhou J#, Zou Y, Su Z, Gu X*, Paralog-divergent Features May Help Reduce Off-target Effects of Drugs: Hints from Glucagon Subfamily Analysis, Genomics, Proteomics & Bioinformatics, 2017,15(4):246-254
Zhou Z, Zou Y, Zhou J, Zhao S, Su Z, Gu X*. Mutation-profile-based methods for understanding selection forces in cancer somatic mutations: a comparative analysis. Oncotarget, 2017,8(35):58835-58846
