個(gè)人簡(jiǎn)介：
2012年于中央民族大學(xué)獲生物科學(xué)學(xué)士學(xué)位,，2018年于蘇州大學(xué)功能納米與軟物質(zhì)研究院獲化學(xué)博士學(xué)位。2018-2020年于上海交通大學(xué)醫(yī)學(xué)院公共衛(wèi)生學(xué)院從事博士后研究,。
2020-2022年受聘于上海交通大學(xué)醫(yī)學(xué)院公共衛(wèi)生學(xué)院,，任助理研究員。2022年起任上海交通大學(xué)醫(yī)學(xué)院公共衛(wèi)生學(xué)院副研究員,。2018年獲上海市“超級(jí)博士后”激勵(lì)計(jì)劃資助,。2022年獲上海交通大學(xué)醫(yī)學(xué)院”九龍醫(yī)學(xué)優(yōu)秀青年人才獎(jiǎng)“。2022年入選上海市衛(wèi)健委”衛(wèi)生健康青年人才計(jì)劃“,。主持國自然青年基金項(xiàng)目和上海市自然科學(xué)基金面上項(xiàng)目,。
研究方向和成果:
多年來從事耐藥性腫瘤防控新策略的發(fā)展和應(yīng)用。針對(duì)腫瘤干細(xì)胞擴(kuò)增和營養(yǎng)代謝異常等腫瘤微環(huán)境特征,，通過設(shè)計(jì)新型生物材料,，發(fā)展精準(zhǔn)靶向腫瘤基質(zhì)細(xì)胞、抗原呈遞細(xì)胞和免疫抑制性細(xì)胞的代謝干預(yù)技術(shù),，增強(qiáng)腫瘤對(duì)化療和免疫療法的敏感性,，并有效地預(yù)防腫瘤的復(fù)發(fā)和轉(zhuǎn)移。作為第一作者或通訊作者發(fā)表發(fā)表SCI論文16篇（其中9篇影響因子大于25,；平均影響因子19.7）,。
代表性文章：
（#：共同第一作者；*：通訊作者,；IF：影響因子）
1. Liang H#, Xu C#, Guo D#, Peng F, Chen N*, Song H*, Ji X*. Dismantlable Coronated Nanoparticles for Coupling the Induction and Perception of Immunogenic Cell Death. Adv. Mater. 2024 Apr 21; 2313097. (IF=29.4)
2. Guo D#, Ji X#*, Xie H, Ma J, Xu C, Zhou Y, Chen N, Wang H*, Fan C*, Song H*. Targeted Reprogramming of Vitamin B3 Metabolism as a Nanotherapeutic Strategy towards Chemoresistant Cancers. Adv. Mater. 2023 June; 35:e2301257. (IF=29.4)
3. Xu C#, Ji X#*, Zhou Y, Cheng Y, Guo D, Li Q, Chen N*, Fan C*, Song H*. Slimming and Reinvigorating Tumor-Associated Dendritic Cells with Hierarchical Lipid Rewiring Nanoparticles. Adv. Mater. 2023 Apr; 35:e2211415. (IF=29.4)
4. Ma J#, Guo D#, Ji X#, Zhou Y, Liu C, Li Q, Zhang J*, Fan C*, Song H*.Composite Hydrogel for Spatiotemporal Lipid Intervention of Tumor Milieu. Adv. Mater. 2023 Apr 6; 35(14):e2211579. (IF=29.4)
5. Ji X, Li Q, Song H*, Fan C*. Protein-Mimicking Nanoparticles in Biosystems. Adv. Mater. 2022 Sep 15; 34(37):e2201562. (IF=29.4)
6. Ji X, Zhou Y, Li Q, Song H*, Fan C*. Protein-Mimicking Nanoparticles for a Cellular Regulation of Homeostasis. ACS Appl. Mater. Interfaces 2021 Jul 14;13(27):31331-31336. (IF=9.5)
7. Ji X, Guo D, Ma J, Yin M, Yu Y; Liu C; Zhou Y, Sun J, Li Q, Chen N*, Fan C*, Song H*. Epigenetic Remodeling Hydrogel Patches for Multidrug-resistant Triple-negative Breast Cancer. Adv. Mater. 2021, 33: 2100949. (IF=29.4)
8. Zhang L#, Ji X#, Su Y*, Zhai X, Xu H, Song B, Jiang A, Guo D, He Y*. Fluorescent silicon nanoparticles-based nanotheranostics agents for rapid diagnosis and treatment of bacteria-induced keratitis. Nano Res. 2021, 14: 52-58. (IF=9.9)
9. Guo D#, Ji X#, Peng F, Zhong Y, Chu B, Su Y*, He Y*. Photostable and biocompatible fluorescent silicon nanoparticles for imaging-guided co-delivery of siRNA and doxorubicin to drug-resistance cancer cells. Nano-Micro Letters 2019, 11:27. (IF=26.6)
10. Ji X, Peng F, Zhong Y, Su Y, Jiang X, Song C, Yang L, Chu B, Lee S*, He Y*. Highly fluorescent, photostable, and ultrasmall silicon drug nanocarriers for long-term tumor cell tracking and in-vivo cancer therapy. Adv. Mater. 2015, 27: 1029-1034. (IF=29.4)
11. Su Y#*, Ji X#, He Y*. Water-dispersible fluorescent silicon nanoparticles and their optical applications. Adv. Mater. 2016, 28: 10567-10574. (IF=29.4)
12. Ji X#, Guo D#, Song B, Wu S, Chu B, Su Y, He Y*. Traditional chinese medicine molecules-assisted chemical synthesis of fluorescent anti-cancer silicon nanoparticles. Nano Res. 2018, 11: 5627-5641. (IF=9.9)
13. Ji X#, Wang C#, Tang M, Guo D, Peng F, Zhong Y, Song B, Su Y*, He Y*. Biocompatible protamine sulfate@silicon nanoparticles-based gene nanocarriers featuring strong and stable fluorescence. Nanoscale 2018, 10: 14455-14463. (IF=6.7)
