個(gè)人簡(jiǎn)介：2021年畢業(yè)于中國(guó)科學(xué)院大學(xué)上海營(yíng)養(yǎng)與健康研究所,，獲得醫(yī)學(xué)博士學(xué)位,，專業(yè)方向?yàn)槊庖邔W(xué)；2021-2023年在上海交通大學(xué)醫(yī)學(xué)院公共衛(wèi)生學(xué)院從事博士后研究工作,；2023.12-至今進(jìn)入上海交通大學(xué)醫(yī)學(xué)院公共衛(wèi)生學(xué)院工作,。主要從事慢性肝臟疾病及相關(guān)腫瘤的防治研究。近年來(lái),，研究成果以第一/共同第一作者的身份發(fā)表在Gut,、Nature Communications、Cell Reports Medicine,、Journal For Immunotherapy of cancer,、Cardiovascular Diabetology、Clinical and Translational Medicine等國(guó)際一流雜志,，共發(fā)表SCI研究論文16余篇,，綜述1篇。
主持項(xiàng)目：國(guó)家自然科學(xué)基金青年項(xiàng)目,、中國(guó)博士后科學(xué)基金站中特別資助,，中國(guó)博士后科學(xué)基金面上資助。
獎(jiǎng)勵(lì)榮譽(yù)：2024年獲上海市啟明星項(xiàng)目（揚(yáng)帆專項(xiàng)）,，2021年獲上海市超級(jí)博士后資助,，2021年獲上海交通大學(xué)醫(yī)學(xué)院博后激勵(lì)計(jì)劃資助。
研究領(lǐng)域：慢性肝臟疾病及相關(guān)腫瘤的防治研究
1,、圍繞“病因發(fā)現(xiàn)-功能及靶點(diǎn)研究-靶向干預(yù)”的核心研究策略,，通過(guò)深入研究相關(guān)病因如何調(diào)控肝臟組織穩(wěn)態(tài)進(jìn)而影響慢性肝病及肝癌發(fā)生發(fā)展及藥物應(yīng)答，發(fā)現(xiàn)治療的新靶點(diǎn),。
2,、探索主動(dòng)健康生活方式（如膳食營(yíng)養(yǎng)、情緒壓力,、運(yùn)動(dòng)等）在慢性肝臟疾病及相關(guān)腫瘤的防治中的作用及機(jī)制研究,。
3,、探索慢病及共病模式的主動(dòng)健康管理策略研究
代表性成果：
1. Y. Yang, Pei T, Liu C, Cao M, Hu X, Yuan J, Chen F, Guo B, Hong Y, Liu J, Li B, Li X, Wang H*. Glutamine metabolic competition drives immunosuppressive reprogramming of intratumour GPR109A+ myeloid cells to promote liver cancer progression. Gut. 2025. (第一作者，IF=23.1)
2. Yang Y, Pei T, Hu X, Lu Y, Huang Y, Wan T, Liu C, Chen F, Guo B, Hong Y, Ba Q, Li X, Wang H. Dietary vitamin B3 supplementation induces the antitumor immunity against liver cancer via biased GPR109A signaling in myeloid cell. Cell Reports Medicine. 2024 Sep 17;5(9):101718. (第一作者,，IF=11.7)
3. Huang Y, Zhou Y, Xu Y, Wang X, Zhou Z, Wu K, Meng Q, Wang L, Yang Y, Gao H, Ji J, Jiang X, Yang Y*, Hao L, Wang H. Inflammatory markers link triglyceride-glucose index and obesity indicators with adverse cardiovascular events in patients with hypertension: insights from three cohorts. Cardiovascular Diabetology 24, 11 (2025). (共同通訊,，IF=8.5)
4. Y. Yang, M. Sun, W. Yao, F. Wang, X. Li, W. Wang, J. Li, Z. Gao, L. Qiu, R. You, C. Yang, Q. Ba, H. Wang, Compound kushen injection relieves tumor-associated macrophage-mediated immunosuppression through TNFR1 and sensitizes hepatocellular carcinoma to sorafenib. Journal for ImmunoTherapy of Cancer. 2020;8: e000317. (第一作者，IF=13.751)
5. Y. Yang, M. Sun, W. Li, C. Liu, Z. Jiang, P. Gu, J. Li, W. Wang, R. You, Q. Ba, X. Li, H. Wang. Rebalancing TGF-β/Smad7 signaling via Compound kushen injection in hepatic stellate cells protects against liver fibrosis and hepatocarcinogenesis. Clinical and Translational Medicine. 2021;11: e410. (第一作者,，IF=11.492)
6. C. Liu, Y. Yang, C. Chen, L. Li, J. Li, X. Wang, Q. Chu, L. Qiu, Q. Ba, X. Li, H. Wang. Environmental eustress modulates β-ARs/CCL2 axis to induce anti-tumor immunity and sensitize immunotherapy against liver cancer in mice. Nature Communications, 2021, 12:5725. (共同第一作者,，IF=17.694)
7. Y.Yang, Y. Lu, T. Pei, B. Guo, J. Li, H. Wang, Q. Ba. Compound kushen injection in cancer treatments: E?cacy, active ingredients, and mechanisms. Pharmacological Research - Modern Chinese Medicine. 2022; 3:100108. (第一作者)
8. M. Sun, P. Gu, Y. Yang, L. Yu, Z. Jiang, J. Li, Y. Chen, Q. Ba, H. Wang. Mesoporous silica nanoparticles inflame tumors to overcome anti-PD-1 resistance through TLR4-NFκB axis. Journal for ImmunoTherapy of Cancer. 2021; 9:e002508. (共同第一作者，IF=13.751)
9. Huang Y, Xu J, Yang Y, Wan T, Wang H*, Li X*. Association between Lifestyle Modification and All-Cause, Cardiovascular, and Premature Mortality in Individuals with Non-Alcoholic Fatty Liver Disease. Nutrients. 2024 Jun 28;16(13):2063. (共同第一作者,，IF=4.8)
10. Pu Yang, Jie Pan, Haibo Wang, Xu Xiaohan, Xu Zeling, Xuenhong Chen, Yang Yang, Hongzhe Sun, Meng Li, Olivier Habimana. Structural, metagenomic and metabolic shifts in multispecies freshwater biofilm models exposed to silver nanoparticles. Journal of Environmental Chemical Engineering, 2023, 11(1): 109162.
11. Bai PY, Chen SQ, Jia DL, Pan LH, Liu CB, Liu J, Luo W, Yang Y, Sun MY, Wan NF, Rong WW, Sun AJ, Ge JB. Environmental eustress improves postinfarction cardiac repair via enhancing cardiac macrophage survival. Science Advances. 2022 Apr 29;8(17): eabm3436.
12. Li Y, Zhang L, Ren P, Yang Y, Li S, Qin X, Zhang M, Zhou M, Liu W. Qing-Xue-Xiao-Zhi formula attenuates atherosclerosis by inhibiting macrophage lipid accumulation and inflammatory response via TLR4/MyD88/NF-κB pathway regulation. Phytomedicine. 2021 Dec; 93:153812.
13. Gu P, Sun M, Li L, Yang Y, Jiang Z, Ge Y, Wang W, Mu W, Wang H. Breast Tumor-Derived Exosomal MicroRNA-200b-3p Promotes Specific Organ Metastasis Through Regulating CCL2 Expression in Lung Epithelial Cells. Frontiers in Cell and Developmental Biology. 2021 Jun 24; 9:657158.
14. Pu Y, Pan J, Yao Y, Ngan WY, Yang Y, Li M, Habimana O. Ecotoxicological effects of erythromycin on a multispecies biofilm model, revealed by metagenomic and metabolomic approaches. Environmental Pollution. 2021 May 1; 276:116737.
15. Jiang Z, Mu W, Yang Y, Sun M, Liu Y, Gao Z, Li J, Gu P, Wang H, Lu Y, Ba Q, Wang H. Cadmium exacerbates dextran sulfate sodium-induced chronic colitis and impairs intestinal barrier. Science of The Total Environment. 2020 Nov 20; 744:140844.
16. Huang C, Sun M, Yang Y, Wang F, Ma X, Li J, Wang Y, Ding Q, Ying H, Song H, Wu Y, Jiang Y, Jia X, Ba Q, Wang H. Titanium dioxide nanoparticles prime a specific activation state of macrophages. Nanotoxicology. 2017 Aug; 11(6):737-750.
