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流行病學(xué)與生物統(tǒng)計學(xué)系

黃亨燁/ 職稱:實驗師

學(xué)歷學(xué)位:碩士 研究生

Email: [email protected],,[email protected]

個人簡介

2010年參加工作,,曾在國家衛(wèi)生部數(shù)據(jù)中心、知名醫(yī)藥公司擔(dān)任醫(yī)學(xué)統(tǒng)計分析師及部門主管多年。為多家知名藥企,、三甲醫(yī)院的高級咨詢顧問,,提供臨床試驗方案設(shè)計,、統(tǒng)計分析與數(shù)據(jù)挖掘,、Meta分析等咨詢工作,有豐富的培訓(xùn)和實戰(zhàn)經(jīng)驗,。目前就職于上海交通大學(xué)醫(yī)學(xué)院,,現(xiàn)為公共衛(wèi)生學(xué)院流行病學(xué)與生物統(tǒng)計學(xué)系教師。近五年發(fā)表SCI文章17篇,,總影響因子超100分,,平均6.2分,為中華系列醫(yī)學(xué)雜志特約撰稿發(fā)表臨床研究方法學(xué)論文多篇,。評審臨床研究項目100余項,,負責(zé)多中心臨床試驗項目的設(shè)計與管理、主持開發(fā)EDC系統(tǒng)10余項,,為國家科技部重點研發(fā)計劃精準(zhǔn)醫(yī)學(xué)研究項目組主要成員,,為交大協(xié)同創(chuàng)新團隊成員。

承擔(dān)教學(xué)工作

主講研究生《高級衛(wèi)生統(tǒng)計學(xué)》,,本科生《衛(wèi)生統(tǒng)計學(xué)》,、《醫(yī)學(xué)統(tǒng)計學(xué)》、《流行病學(xué)》,、《科研數(shù)據(jù)管理與統(tǒng)計分析》等課程,。

主要研究方向

統(tǒng)計建模、臨床研究方法學(xué),、數(shù)據(jù)管理技術(shù)等,。

主要研究成果

Zhou C, Shi Y, Chai P, Wu F, Xia W, He X, Shi Y,Huang H, Jia R, Fan X. Contemporary update of overall prognosis and nomogram to predict individualized survival for Chinese patients with eyelid sebaceous carcinoma. EBioMedicine. 2018 Oct;36:221-228.(*co-Corresponding author, IF=8.143)


Qian Y, Yu S, Shi Y,Huang H, Fan C. Risk Factors for the Occurrence and Progression of Posttraumatic Elbow Stiffness: A Case-Control Study of 688 Cases. Front Med (Lausanne). 2020 Dec 16;7:604056.(*co-Corresponding author, IF=5.019)


Li X,Huang H, Xu H, Shi Y, Qian Y, Zou J, Yi H, Guan J, Yin S. Excessive daytime sleepiness, metabolic syndrome, and obstructive sleep apnea: two independent large cross-sectional studies and one interventional study. Respir Res. 2019 Dec 4;20(1):276.(*co-first author, IF=5.631)


Wang F, Xiong X, Xu H,Huang H, Shi Y, Li X, Qian Y, Zou J, Yi H, Guan J, Yin S. The association between obstructive sleep apnea syndrome and metabolic syndrome: a confirmatory factor analysis. Sleep Breath. 2019 Sep;23(3):1011-1019.(*co-Corresponding author, IF=2.816)


Xu H, Zhao X, Shi Y, Li X, Qian Y, Zou J, Yi H,Huang H, Guan J, Yin S. Development and validation of a simple-to-use clinical nomogram for predicting obstructive sleep apnea. BMC Pulm Med. 2019 Jan 18;19(1):18.(*co-Corresponding author, IF=3.317)


Jing J, Yinchen S, Xia C, Jing W, Chong C, Xun X,Hengye H, Kun L. Pharmacogenomic study on anti-VEGF medicine in treatment of macular Neovascular diseases: a study protocol for a prospective observational study. BMC Ophthalmol. 2018 Jul 24;18(1):181.(*co-Corresponding author, IF=2.209)


Ji M, Genchev GZ,Huang H, Xu T, Lu H, Yu G. Evaluation Framework for Successful Artificial Intelligence-Enabled Clinical Decision Support Systems: Mixed Methods Study. J Med Internet Res. 2021 Jun 2;23(6):e25929. doi: 10.2196/25929. PMID: 34076581.


Shen L, Qiu L, Liu D, Wang L,Huang H, Ge H, Xiao Y, Liu Y, Jin J, Liu X, Wang DW, Peterson ED, He B, Zhou N. The Association of Low Molecular Weight Heparin Use and In-hospital Mortality Among Patients Hospitalized with COVID-19. Cardiovasc Drugs Ther. 2021 Jan 4:1–8.


Xu P, Guo R, You J, Cheng S, Li J, Zhong H, Sun C, Xu H,Huang H, Li B, Zhao W. Dynamic evaluation of the prognostic value of 18F-FDG PET/CT in extranodal NK/T-cell lymphoma, nasal type. Ann Hematol. 2021 Apr;100(4):1039-1047.


Shen R, Xu PP, Wang N, Yi HM, Dong L, Fu D, Huang JY,Huang HY, Janin A, Cheng S, Wang L, Zhao WL. Influence of oncogenic mutations and tumor microenvironment alterations on extranodal invasion in diffuse large B-cell lymphoma. Clin Transl Med. 2020 Nov;10(7):e221.


Guo R, Xu P, Cheng S, Lin M, Zhong H, Li W,Huang H, Ouyang B, Yi H, Chen J, Lin X, Shi K, Zhao W, Li B. Comparison of Nasopharyngeal MR, 18 F-FDG PET/CT, and 18 F-FDG PET/MR for Local Detection of Natural Killer/T-Cell Lymphoma, Nasal Type. Front Oncol. 2020 Oct 14;10:576409.


Zhong H, Chen J, Cheng S, Chen S, Shen R, Shi Q, Xu P,Huang H, Zhang M, Wang L, Wu D, Zhao W. Prognostic nomogram incorporating inflammatory cytokines for overall survival in patients with aggressive non-Hodgkin's lymphoma. EBioMedicine. 2019 Mar;41:167-174.


Chen C, Chen X,Huang H, Han C, Qu Y, Jin H, Niu T, Zhang Y, Liu K, Xu X. Elevated plasma and vitreous levels of leucine-rich-α2-glycoprotein are associated with diabetic retinopathy progression. Acta Ophthalmol. 2019 May;97(3):260-264.


Xu PP, Fu D, Li JY, Hu JD, Wang X, Zhou JF, Yu H, Zhao X,Huang YH, Jiang L, Liu F, Su LP, Chen ZW, Zeng QS, Chen JP, Fang MY, Ma J, Liu T, Song YP, Yu K, Li Y, Qiu LG, Chen XQ, Gu J, Yan JS, Hou M, Huang HY, Wang L, Cheng S, Shen Y, Xiong H, Chen SJ, Zhao WL. Anthracycline dose optimisation in patients with diffuse large B-cell lymphoma: a multicentre, phase 3, randomised, controlled trial. Lancet Haematol. 2019 Jun;6(6):e328-e337.


Liu K, Song Y, Xu G, Ye J, Wu Z, Liu X, Dong X, Zhang M, Xing Y, Zhu S, Chen X, Shen Y,Huang H, Yu L, Ke Z, Rosenfeld PJ, Kaiser PK, Ying G, Sun X, Xu X; PHOENIX Study Group. Conbercept for Treatment of Neovascular Age-related Macular Degeneration: Results of the Randomized Phase 3 PHOENIX Study. Am J Ophthalmol. 2019 Jan;197:156-167.

Xu PP, Xiong J, Cheng S, Zhao X, Wang CF, Cai G, Zhong HJ,Huang HY, Chen JY, Zhao WL. A Phase II Study of Methotrexate, Etoposide, Dexamethasone and Pegaspargase Sandwiched with Radiotherapy in the Treatment of Newly Diagnosed, Stage IE to IIE Extranodal Natural-Killer/T-Cell Lymphoma, Nasal-Type. EBioMedicine. 2017 Nov;25:41-49.


Xu H, Wang H, Guan J, Yi H, Qian Y, Zou J, Xia Y, Fu Y, Li X, Jiao X,Huang H, Dong P, Yu Z, Yang J, Xiang M, Li J, Chen Y, Wang P, Sun Y, Li Y, Zheng X, Jia W, Yin S. Effects of continuous positive airway pressure on neurocognitive architecture and function in patients with obstructive sleep apnoea: study protocol for a multicentre randomised controlled trial. BMJ Open. 2017 May 25;7(5):e014932.


黃亨燁,施悅,仇玉蘭,等.國內(nèi)臨床試驗方案常見問題與報告規(guī)范的探討[J].中華醫(yī)學(xué)科研管理雜志, 2018, 31(3):134-139.


黃亨燁,張碩,馮鐵男,等.大學(xué)附屬醫(yī)院醫(yī)師臨床研究能力與培訓(xùn)需求分析[J].中華醫(yī)學(xué)科研管理雜志, 2017, 30(8):238-244.


統(tǒng)計建模方法的理論研究及應(yīng)用:傾向性得分匹配(PSM),逆概率加權(quán)(IPW),,列線圖(Nomogram),,分類回歸樹(CART),結(jié)構(gòu)方程模型(SEM),,潛在分類和潛在剖面分析(LCA/LPA),,混合因子模型(FFM),工具變量(IV),廣義線性模型(GLM),,神經(jīng)網(wǎng)絡(luò)模型(NN),,診斷性研究(DS),時間序列分析(TSA),,薈萃分析(Meta),,LASSO回歸等統(tǒng)計學(xué)方法/模型在醫(yī)學(xué)科研中的應(yīng)用。

獲得榮譽稱號

2020年獲上海市高校青年教師教學(xué)競賽二等獎