個(gè)人簡(jiǎn)介
尹勝菊,,醫(yī)學(xué)博士,,現(xiàn)任上海交通大學(xué)公共衛(wèi)生學(xué)院副研究員。2013年獲得北京大學(xué)醫(yī)學(xué)博士學(xué)位,,2018年至2021年在北京大學(xué)公共衛(wèi)生學(xué)院和基礎(chǔ)醫(yī)學(xué)院從事博士后研究工作,。主要研究方向?yàn)榄h(huán)境污染與婦幼健康,環(huán)境污染與出生缺陷,。
迄今為止,,在Journal of hazardous material、Environment International,、Science of the total environment,、Pharmacogenetics and genomics等雜志發(fā)表中英文學(xué)術(shù)論文24篇,其中第一/共同第一作者論文9篇(中科院一區(qū)2篇,,JCR一區(qū)6篇),。主持國(guó)家自然科學(xué)基金委、中國(guó)博士后科學(xué)基金委,、北京市自然科學(xué)基金委,、山東省衛(wèi)健委等機(jī)構(gòu)資助科研項(xiàng)目多項(xiàng),作為課題組骨干參與科技部國(guó)家重大研究計(jì)劃項(xiàng)目1項(xiàng),,參與國(guó)自然面上項(xiàng)目多項(xiàng)?,F(xiàn)任中國(guó)婦幼保健協(xié)會(huì)出生缺陷防治與分子遺傳分會(huì)委員,,北京市藥理學(xué)會(huì)藥物代謝專(zhuān)業(yè)委員會(huì)委員。
社會(huì)任職/學(xué)術(shù)頭銜
中國(guó)婦幼保健協(xié)會(huì)出生缺陷防治與分子遺傳分會(huì)委員
北京市藥理學(xué)會(huì)藥物代謝專(zhuān)業(yè)委員會(huì)委員
主要研究方向
環(huán)境污染與婦幼健康,,環(huán)境污染與出生缺陷,。
代表性科研項(xiàng)目
1. 國(guó)家自然科學(xué)基金青年項(xiàng)目,有機(jī)氯農(nóng)藥對(duì)葉酸/同型半胱氨酸代謝的干擾作用研究,,2021.01-2023.12,,主持。
2. 北京市自然科學(xué)基金青年基金項(xiàng)目,,鎘暴露致胎兒唇腭裂作用及DNA甲基化機(jī)制研究,,2021.01-2022.12,主持,。
3. 中國(guó)博士后科學(xué)基金第69批面上資助,,鎘元素暴露與神經(jīng)管缺陷的關(guān)系及致畸機(jī)制研究,2021.01-2021.12,,主持,。
4. 山東省醫(yī)藥衛(wèi)生科技發(fā)展計(jì)劃面上項(xiàng)目,抗癲癇藥物丙戊酸鈉的藥物代謝酶和轉(zhuǎn)運(yùn)載體基因多態(tài)性與其藥物代謝動(dòng)力學(xué)的相關(guān)性研究,,2016.01-2018.12,,主持。
5. 國(guó)家重點(diǎn)研發(fā)計(jì)劃項(xiàng)目,,環(huán)境因素導(dǎo)致重要器官發(fā)育異常的關(guān)鍵環(huán)節(jié),,2016.07-2021.06,參加,。
近五年代表性研究成果(#共同第一作者,,*通訊作者)
1. Yin S#, Tian T#, Wang C, et al., Prenatal uranium exposure and the risk for fetal neural tube defects: A case-control study in women living in a rural area of northern China. Journal of hazardous materials, 2021. 424(Pt B):127466.
2. Yin S#, Sun Y#, Yu J, et al., Prenatal exposure to organochlorine pesticides is associated with increased risk for neural tube defects. Science of the Total Environment, 2021. 770:145284.
3. Yin S#, Wang C#, Wei J, et al., Essential trace elements in placental tissue and risk for fetal neural tube defects. Environment International, 2020. 139: 105688.
4. Tian T#, Yin S#, Jin L, et al., Single and mixed effects of metallic elements in maternal serum during pregnancy on risk for fetal neural tube defects: A Bayesian kernel regression approach. Environmental Pollution, 2021. 285: 117203.
5. Yin S#, Wei J, Wei Y, et al., Organochlorine pesticides exposure may disturb homocysteine metabolism in pregnant women. Science of the Total Environment, 2020. 708: 135146.
6. Yin S#, Wang C#, Wei J, et al., Selected essential trace elements in maternal serum and risk for fetal orofacial clefts. Science of the Total Environment, 2020. 712: 136542.
7. Yin S#, Qi H#, Wang X, et al., Effects of functional CYP2C8, CYP2C9, CYP3A5, and ABCB1 genetic variants on the pharmacokinetics of insulin sensitizer pioglitazone in Chinese Han individuals. Pharmacogenetics and Genomics, 2017. 27 (4): 125-134.