個人簡介
陳倩,,上海交通大學(xué)醫(yī)學(xué)院兒科學(xué)博士。讀博期間,,以“上海優(yōu)生兒童隊列”為平臺,,學(xué)習(xí)并具備了流行病學(xué)的研究思路和方法,重點關(guān)注生命早期環(huán)境因素暴露對兒童健康的影響,。通過參與“上海優(yōu)生兒童隊列”的跟蹤隨訪工作,,進一步強化了出生隊列隨訪工作的實踐能力;熟練掌握出生隊列中大數(shù)據(jù)的收集、儲存,、處理與統(tǒng)計分析能力,;同時在實驗室里具備了環(huán)境因素收集、檢測和基礎(chǔ)分子實驗技術(shù),。博士后期間繼續(xù)關(guān)注生命早期因素對兒童過敏性疾病的影響,,并從表觀遺傳學(xué)角度探討可能的分子機制。已累計發(fā)表SCI文章26篇,,其中第一作者/通訊作者12篇,。
主要研究方向
生命早期因素對兒童健康的影響
主要研究課題
1. 國家自然科學(xué)基金面上項目,81273091,,剖宮產(chǎn)對兒童過敏性疾病影響的流行病學(xué)調(diào)查和機制研究,,2013/01-2016/12,結(jié)題,,參與,。
2. 國家自然科學(xué)基金重點項目,81530086,,基于大規(guī)模前瞻性隊列復(fù)雜縱向數(shù)據(jù)的哮喘風(fēng)險評估與預(yù)測模型的建立,,2016/01-2020/12,結(jié)題,,參與,。
3. 國家自然科學(xué)基金委員會,青年科學(xué)基金項目,,81803244,,孕期全氟丁烷磺酸暴露通過調(diào)節(jié)類固醇激素導(dǎo)致兒童肥胖的機制研究,2019-01-01至2021-12-31,,結(jié)題,,主持。
4. 科學(xué)技術(shù)部,,國家重點研發(fā)計劃,,2019YFA0802501,生長發(fā)育期營養(yǎng)失衡對器官發(fā)育的影響及其機制,,2019-12至今,,在研,參與,。
5. 上海市衛(wèi)生健康委,,協(xié)同創(chuàng)新集群計劃,2020CXJQ01,,基于生命早期千天計劃的發(fā)育源性疾病的病因及防治研究,,2020-06至今,,在研,參與,。
主要研究成果
1. Zhang Y, Tang W, Wang Y, Nian M, Jiang F, Zhang J, Chen Q*. Environmental antibiotics exposure in school-age children in Shanghai and health risk assessment: A population-based representative investigation. Science of the Total Environment, 2022, 824:153859.
2. Tang W, Zhan W, Wei M, Chen Q*. Associations Between Different Dietary Vitamins and the Risk of Obesity in Children and Adolescents: A Machine Learning Approach. Frontiers in Endocrinology, 2022, 12: 816975.
3. Zhan W#, Zhu J#, Huo X, Ye J, Chen Q*, Zhang J*. Epidemiology of uterine rupture among pregnant women in China and development of a risk prediction model: analysis of data from a multicentre, cross-sectional study. BMJ Open, 2021, 11(11):e054540. (共同通訊)
4. Chen Q#, Chen J#, Zhou Y, Huang L, Tang Y, Li J*, Zhang J*. Natural history and associated early life factors of childhood asthma: a population registry-based cohort study in Denmark. BMJ Open, 2021, 11:e045728.
5. Chen Q, Ming Y, Gan Y, Huang L, Zhao Y, Wang X, Liu Y, Zhang J. The impact of cesarean delivery on infant DNA methylation. BMC Pregnancy Childbirth, 2021, 21(1):265.
6. Zhang Y, Hua L, Liu QH, Chu SY, Gan YX, Wu M, Bao YX, Chen Q*, Zhang J*. Household mold exposure interacts with inflammation-related genetic variants on childhood asthma: a case-control study. BMC Pulmonary Medicine, 2021, 21(1):114. (共同通訊)
7. Li C#, Chen Q#, Zhang X, Li H, Liu Q, Fei P, Huang L, Yao Z*. Early Life Domestic Pet Ownership, and the Risk of Pet Sensitization and Atopic Dermatitis in Preschool Children: A Prospective Birth Cohort in Shanghai. Frontiers Pediatrics, 2020, 8:192. (共同第一)
8. Chen Q, Zhang X, Zhao Y, Lu W, Wu J, Zhao S, Zhang J*, Huang L*. Prenatal exposure to perfluorobutanesulfonic acid and childhood adiposity: A prospective birth cohort study in Shanghai, China. Chemosphere, 2019, 226;17-23.
9. Zeng X#, Chen Q#, Zhang X, Li H, Liu Q, Li C, Ma M, Zhang J, Zhang W*, Zhang J*, Huang L*. Association between prenatal exposure to perfluoroalkyl substances and asthma-related diseases in preschool children. Environment Science and Pollution Research International, 2019, 26(29):29639-29648. (共同第一)
10. Chen Q, Huang R, Hua L, Guo Y, Huang L, Zhao Y, Wang X, Zhang J*. Prenatal exposure to perfluoroalkyl and polyfluoroalkyl substances and childhood atopic dermatitis: a prospective birth cohort study. Environmental Health, 2018, 17(1):8.
11. Liu H#, Chen Q#, Lei L#, Zhou W, Huang L, Zhang J*, Chen D*. Prenatal exposure to perfluoroalkyl and polyfluoroalkyl substances affects leukocyte telomere length in female newborns. Environmental Pollution, 2018, 235: 446-52. (共同第一)
12. Wang B#, Chen Q#, Shen L, Zhao S, Pang W, Zhang J*, Perfluoroalkyl and polyfluoroalkyl substances in cord blood of newborns in Shanghai, China: Implications for risk assessment. Environment International, 2016, 97:7-14. (共同第一)