個人簡介
徐健,，主任醫(yī)師,，博士生導師，國際和平婦幼保健院兒?？祻涂瓶浦魅巍Ｈ脒x上海市科委啟明星計劃,、上海市教委高峰高原項目“研究型醫(yī)師”計劃,、上海交通大學優(yōu)秀青年教師等。
社會任職/學術(shù)頭銜
擔任上海市微量元素學會秘書長,、中國福利會宋慶齡兒童發(fā)展中心兼職教授,、中華醫(yī)學會公共衛(wèi)生分會青年委員會副主任委員、Neuroscience bulletin雜志青年編委等,。
主要研究方向
致力于兒童保健和環(huán)境健康交叉領(lǐng)域的重要問題和難點問題,。長期進行兒童重金屬暴露、兒童微量元素營養(yǎng),、兒童神經(jīng)心理發(fā)育障礙（如智能發(fā)育落后,、多動癥、自閉癥,、抽動癥及其他相關(guān)心理行為認知問題）的研究,。
主要研究課題
主要是利用出生隊列、臨床研究,、基礎(chǔ)研究等方式,，系統(tǒng)進行了包括（1）生命早期重金屬暴露對兒童神經(jīng)心理發(fā)育的影響及影響機制研究：如生命早期鉛、汞,、錳暴露,。（2）生命早期不良的精神情緒壓力對兒童神經(jīng)心理發(fā)育的影響及影響機制研究。
主要研究成果
在Science of the Total Environment,、The International Journal of Hygiene and Environmental Health,、Environmental Health Perspectives、Ecotoxicology and Environmental Safety,、Environmental Research,、Environ International、The Journal of Pediatrics,、obesity,、Developmental Cognitive Neuroscience、Child Adolesc Psychiatry Ment Health,。等SCI期刊發(fā)表50多篇論文,。主譯/副主譯/參編6本領(lǐng)域內(nèi)專著。作為負責人主持國家自然基金項目4項,。
近5年主要論文：
1. Yu T, Xu D, Fan J, Hua H, Guo X, Zhang Y, Jiang S, Huang L, Jiang Y, Wang Y, Yan C, Xu J* (徐健). Homework, sleep insufficiency and adolescent neurobehavioral problems: Shanghai Adolescent Cohort. J Affect Disord. 2023 Jul 1;332:273-282. doi: 10.1016/j.jad.2023.04.008. Epub 2023 Apr 12. PMID: 37059191.
2. Yu T, Jiang Y, Fan J, Guo X, Hua H, Xu D, Wang Y, Yan C, Xu J* (徐健). Rapid increases in BMI waist to height ratio during adolescence and subsequent neurobehavioral deficits. Obesity (Silver Spring). 2023 Nov;31(11):2822-2833. doi: 10.1002/oby.23881. Epub 2023 Sep 21. PMID: 37735781.
3. Hua H, Huang L, Yang B, Jiang S, Zhang Y, Liu J, Yan C, Xu J* (徐健). The mediating role of gut microbiota in the associations of prenatal maternal combined exposure to lead and stress with neurodevelopmental deficits in young rats. Ecotoxicol Environ Saf. 2023 Apr 15;255:114798. doi: 10.1016/j.ecoenv.2023.114798. Epub 2023 Mar 20. PMID: 36948003.
4. Peng, JY; Gao, ZY; Xu J* (徐健); Lin, YF; Specht, AJ; Chen, SW; Nie, LH ; Huang, LH ; Yan, CH*. Concurrent Assessment on Blood Lead in Young Children and Toy Lead in Shanghai. EXPOSURE AND HEALTH. 2023.DOI10.1007/s12403-023-00582-9
5. Yu T, Xu J* (徐健), Jiang Y, Hua H, Zhou Y, Guo X. School educational models and child mental health among K-12 students: a scoping review. Child Adolesc Psychiatry Ment Health. 2022;16(1):32. doi:10.1186/s13034-022-00469-8.
6. Guo X#, Jiang S#, Xu J Xu J* (徐健), Tian Y, Ouyang F, Yu X, Liu J, Yan C, Zhang J; Shanghai Birth Cohort. Effects of single and combined exposure to lead and stress during pregnancy on offspring neurodevelopment. Developmental Cognitive Neuroscience. 2022; 56:101124. doi:10.1016/j.dcn.2022.101124.
7. Guo X, Wang H, Xu J (徐健)*, Hua H. Impacts of vitamin A deficiency on biological rhythms: Insights from the literature. Front Nutr. 2022 Nov 18;9:886244.
8. Yu T, Zhou L, Xu J* (徐健), Kan H, Chen R, Chen S, Hua H, Liu Z, Yan C. Effects of prenatal exposures to air sulfur dioxide/nitrogen dioxide on toddler neurodevelopment and effect modification by ambient temperature. Ecotoxicol Environ Saf. 2021;230:113118. doi:10.1016/j.ecoenv.2021.113118.
9. Guo X#, Zhou Y#, Xu J* (徐健), Hu Y, Liu Z. The Association of Maternal Emotional Status With Child Over-Use of Electronic Devices During the COVID-19 Pandemic. Front Pediatr. 2021;9:760996. doi:10.3389/fped.2021.760996
10. Guo X, Zhou L, Xu J* (徐健), Liu Z, Liu J, Yan C. Prenatal Maternal Low Selenium, High Thyrotropin, and Low Birth Weights. Biol Trace Elem Res. 2021;199(1):18-25. doi:10.1007/s12011-020-02124-9
11. Huang L#, Jiang S#, Xu J* (徐健), Lei X, Zhang J. Associations between prepregnancy body mass index, gestational weight gain and weight catch‐up in small‐for‐gestational‐age children. Maternal & Child Nutrition. Published online July 22, 2021. doi:10.1111/mcn.13235
12. Guo X#, Hua H#, Xu J* (徐健), Liu Z. Associations of childhood unintentional injuries with maternal emotional status during COVID-19. BMC Pediatrics. 2021;21(1):422. doi:10.1186/s12887-021-02846-2.
13. Li MM, Gao ZY, Dong CY, Wu MQ, Yan J, Cao J, Ma WJ, Wang J, Gong YL, Xu J* (徐健), Cai SZ, Chen JY, Xu SQ, Tong S, Tang D, Zhang J, Yan CH. Contemporary blood lead levels of children aged 0-84?months in China: A national cross-sectional study. Environ Int. 2020;134:105288. doi:10.1016/j.envint.2019.105288
14. Zhang Y#, Zhou L#, Li S, Liu J, Sun S, Ji X, Yan C, Xu J* (徐健). Impacts of lead exposure and chelation therapy on bone metabolism during different developmental stages of rats. Ecotoxicol Environ Saf. 2019;183:109441. doi:10.1016/j.ecoenv.2019.109441.
15. Xu J* (徐健), Hu H*, Wright R, Schnaas L, Bellinger DC, Park SK, Wright RO, Téllez-Rojo MM. Prenatal lead exposure modifies the association of maternal self-esteem with child adaptive ability. Int J Hyg Environ Health. 2019;222(1):68-75. doi:10.1016/j.ijheh.2018.08.005
16. Lin Y#, Huang L#, Xu J* (徐健), Specht AJ, Yan C, Geng H, Shen X, Nie LH*, Hu H. Blood lead, bone lead and child attention-deficit-hyperactivity-disorder-like behavior. Sci Total Environ. 2019;659:161-167. doi:10.1016/j.scitotenv.2018.12.219
17. Jiang S#, Yang B#, Xu J* (徐健), Liu Z, Yan C, Zhang J, Li S, Shen X. Associations of Internal-Migration Status with Maternal Exposure to Stress, Lead, and Selenium Deficiency Among Pregnant Women in Shanghai, China. Biol Trace Elem Res. 2019;190(2):309-317. doi:10.1007/s12011-018-1570-0
18. Huo X, Chu S, Hua L, Bao Y, Du L, Xu J Xu J* (徐健), Zhang J*. The effect of breastfeeding on the risk of asthma in high-risk children: a case-control study in Shanghai, China. BMC Pregnancy Childbirth. 2018;18(1):341. doi:10.1186/s12884-018-1936-5
19. Specht AJ, Lin Y, Xu J (徐健), Weisskopf M, Nie LH. Bone lead levels in an environmentally exposed elderly population in shanghai, China. Sci Total Environ. 2018;626:96-98. doi:10.1016/j.scitotenv.2018.01.091
20. Ying XL, Gao ZY, Yan J, Zhang M, Wang J, Xu J Xu J (徐健), Markowitz M, Yan CH. Sources, symptoms and characteristics of childhood lead poisoning: experience from a lead specialty clinic in China. Clin Toxicol (Phila). 2018;56(6):397-403. doi:10.1080/15563650.2017.1391392
21. Lin Y, Xu J Xu J* (徐健), Huang J, Jia Y, Zhang J, Yan C, Zhang J. Effects of prenatal and postnatal maternal emotional stress on toddlers’ cognitive and temperamental development. J Affect Disord. 2017;207:9-17. doi:10.1016/j.jad.2016.09.010
22. Li S, Xu J* (徐健), Liu Z, Yan CH. The non-linear association between low-level lead exposure and maternal stress among pregnant women. Neurotoxicology. 2017;59:191-196. doi:10.1016/j.neuro.2016.07.005
23. Zhou L, Xu J Xu J* (徐健), Zhang J, Yan C, Lin Y, Jia Y, Hu W. Prenatal maternal stress in relation to the effects of prenatal lead exposure on toddler cognitive development. Neurotoxicology. 2017;59:71-78. doi:10.1016/j.neuro.2017.01.008
24. Specht AJ, Mostafaei F, Lin Y, Xu J* (徐健), Nie LH*. Measurements of Strontium Levels in Human Bone In Vivo Using Portable X-ray Fluorescence (XRF). Appl Spectrosc. 2017;71(8):1962-1968. doi:10.1177/0003702817694383
25. Lin Y#, Zhou L#, Xu J Xu J* (徐健), Luo Z, Kan H, Zhang J, Yan C, Zhang J. The impacts of air pollution on maternal stress during pregnancy. Scientific Reports. 2017;7(1):40956. doi:10.1038/srep40956
26. Lin Y, Hu W, Xu J Xu J* (徐健), Luo Z, Ye X, Yan C, Liu Z, Tong S. Association between temperature and maternal stress during pregnancy. Environmental Research. 2017;158:421-430. doi:10.1016/j.envres.2017.06.0
