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NRF2, the Dr Jekyll and Mr Hyde, of fatty liver disease and cancer

May 8, 2025 Share:


Professor Michael Karin, member of US National Academy of Sciences and Institute of Medicine, is currently Distinguished Professor in the Departments of Pharmacology and Pathology at the University of California, San Diego.

Professor Michael Karin is highly regarded in the signal transduction community, he pioneered the JNK signaling pathway research, and the first cloning of the IKK gene. Professor Karin’s research interests focus on basic biochemical and cell biological processes that control innate immunity and inflammation and their contribution to cancer and metabolic disease. His group also investigates the interaction between chronic inflammation and immunity during tumor development and therapy.

Professor Karin has served on the editorial board of several international academic journals, including Molecular Cell, Immunity, Cell Metabolism, and Cell Death & Differentiation. He has published more than 490 papers inNature, Cell, Nature Medicine, Immunity and many other prestigious journals, and the number of paper citations ranks top in the world in the field of molecular biology and genetic research. He has won numerous honors including Harvey Prize, The Brupbacher Prize for Cancer Research, The William B. Coley Award for Distinguished Research in Basic and Tumor Immunology, The Anthony Dipple Carcinogenesis Award, AAACR GHA Clowes Award for Outstanding Basic Cancer Research, Fellow of the AACR Academy and has been an Einstein Professorship, Chinese Academy of Sciences in 2009.