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Molecular engineering of photo-activatable prodrug

June 3, 2025 Share:

 

Molecular engineering of photo-activatable prodrug

Jong Seung Kim Professor

Korea University

Jong Seung Kim, a member of the Korean Academy of Sciences, Distinguished Professor at Korea University, and Vice President of the Korean Chemical Society.Prof.Kim has been engaged in the research of small-molecule drug delivery systems, photodynamic therapy, photothermal therapy, and sonodynamic therapy platforms. His innovative achievements in the medical technology field have significantly promoted the development of precision treatment and diagnostic techniques.He has published more than 700 academic papers with a total of over 63,000 citations and an H-index of 127. He has obtained more than 100 domestic and international intellectual property patent authorizations.

Prof. Kim has led the design ofNI-TA photocatalytic superoxide radical generator that overcomes the limitations of traditional photodynamic therapy in tumor hypoxic environments by triggering the pyroptosis mechanism of cancer cells, providing a new strategy for solid tumor treatment. In the field of drug delivery, he constructed a targeted pro-drug system through molecular engineering to achieve controllable release of anticancer drugs at the lesion site and used photosensitizer technology for precise treatment of skin cancer. In addition, his research on the detection of biomarkers for Alzheimer's disease and targeted molecular design provides chemical tools for the early diagnosis and intervention of neurodegenerative diseases. These achievements offer innovative solutions to medical problems such as cancer, chronic infections, and neurological diseases.

Prof.Kim is a Fellow of the Royal Society of Chemistry and a Fellow of the Chinese Chemical Society. Since 2014, he has been continuously rated as a "Global Top 1% Highly Cited Scientist" by Clarivate Analytics. He served as the President of the Korean Chemical Society in 2022 and is currently the Executive Editor-in-Chief of ACS Applied Bio Materials and Associate Editor of iRadiology. He has won the Inmurak Award (2017) and the Korean Science Award (2022).

Host: Prof.Zeyu Xiao | Ministry of Education - Shanghai Biomedical Clinical Translation Collaborative Innovation Center

Time: 2025-5-30 (Friday) 11:15-12:15

Venue:LibraryLecture Hall