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Shanghai Cancer Institute

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LUO Xiaoying

Associate Professor

Email:[email protected]

phone：+862164436795

Research direction:Cancer gene regulation, detection, epigenetics and therapy

Research Interests

  • My laboratory is currently interested in identification and characterization of carcinogenesis and developing. And then develop the detection technology and treatment on cancer. We focus on the mechanism of drug resistance, develop new detection technology to visualize the cancer treatment progression, and develop novel drug delivery system to promote cancer treatment.

Publications

  1. Zhang Y., Pang Y., Xu B., Chen X., Liang S., Hu J., Luo X. Folic acid restricts SARS-CoV-2 invasion by methylating ACE2. Front Microbiol. 2022;13:980903.

  2. Zhang Y., Liang S., Xiao B., Hu J., Pang Y., Liu Y., Yang J., Ao J., Wei L., Luo X. MiR-323a regulates ErbB3/EGFR and blocks gefitinib resistance acquisition in colorectal cancer. Cell Death Dis. 2022;13(3):256.

  3. Lin C., Liang S., Li Y., Peng Y., Huang Z., Li Z., Yang Y., Luo X. Localized plasmonic sensor for direct identifying lung and colon cancer from the blood. Biosens Bioelectron. 2022;211:114372.

  4. Yang Y., Peng Y., Lin C., Long L., Hu J., He J., Zeng H., Huang Z., Li Z. Y., Tanemura M., Shi J., Lombardi J. R., Luo X. Human ACE2-Functionalized Gold "Virus-Trap" Nanostructures for Accurate Capture of SARS-CoV-2 and Single-Virus SERS Detection. Nanomicro Lett. 2021;13:109.

  5. Liu Y., Zhang Y., Xiao B., Tang N., Hu J., Liang S., Pang Y., Xu H., Ao J., Yang J., Liang X., Wei L., Wang Y., Luo X. MiR-103a promotes tumour growth and influences glucose metabolism in hepatocellular carcinoma. Cell Death Dis. 2021;12(6):618.

  6. Wang T., Jin H., Hu J., Li X., Ruan H., Xu H., Wei L., Dong W., Teng F., Gu J., Qin W., Luo X., Hao Y. COL4A1 promotes the growth and metastasis of hepatocellular carcinoma cells by activating FAK-Src signaling. J Exp Clin Cancer Res. 2020;39(1):148.

  7. Tang C., Sun R., Wen G., Zhong C., Yang J., Zhu J., Cong Z., Luo X., Ma C. Bromocriptine and cabergoline induce cell death in prolactinoma cells via the ERK/EGR1 and AKT/mTOR pathway respectively. Cell Death Dis. 2019;10(5):335.

  8. Yang Y., Jin Z., Dong R., Zheng C., Huang Y., Zheng Y., Shen Z., Chen G., Luo X., Zheng S. MicroRNA-29b/142-5p contribute to the pathogenesis of biliary atresia by regulating the IFN-gamma gene. Cell Death Dis. 2018;9(5):545.