WU Zhouwei
chief physician
Graduate Supervisor
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Research area: Clinical medicine/Dermatology and Venereology
Email: [email protected]
Tel: 021-
Research Interests
We focus on the role of aryl hydrocarbon receptor (AhR) in the inflammatory skin diseases, particularly vitiligo, lupus erythematosus, and atopic dermatitis. AhR is an important regulator of skin barrier function. It also controls immune-mediated skin responses. The AhR modulates various physiological functions by acting as a sensor that mediates environment-cell interactions, particularly during immune and inflammatory responses. Diverse experimental systems have been used to assess the AhR's role in skin inflammation. In recent years, an increasing number of studies have accumulated highlighting the regulatory role of AhR in the physiology of the skin. However, there is evidence of both beneficial and harmful effects of AHR signaling.
