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Research Interests

• Our group has developed methods to generate patient-derived organoids (PDO) from tumors, these models recapitulate the histopathologic and molecular architecture of the disease and are broadly used for molecular and genomic studies, drug screening, as well as biomarker discovery. Our studies focus on the following two aspects.

1. To test the role of PDOs to predict drug response to investigate its predictive values.

2. To identify and reconstitute the tumor environment in vitro.