JIA Wei
Research Professor
Doctoral Supervisor
Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Research area: Basic Medicine
Email: [email protected]
Tel: 021-
Research Interests
The long-term research goals of my team are to conduct high-quality, peer-reviewed, grant-funded original research in the areas of systems biology and traditional Chinese medicine in collaboration with clinicians, biologists, bioinformaticians, and epidemiologists.
Our research program combines a series of metabolomics, microbiome, bioinformatics, and molecular biology approaches to the identification of cancer etiology in a variety of tumor types and the mechanistic studies of key metabolic pathways that are critically involved during carcinogenesis.
Our lab operates a state-of-art metabolomics program that quantitatively profiles endogenous small-molecule metabolites and trace elements from biological specimens including blood, urine, saliva, cell lysates, and tissues of experimental animals and human subjects. The program involves:
Targeted analysis of metabolic flux and pathways using isotope labeled metabolites and high sensitivity, high throughput LC-MS-MS and GC-MS platforms.
Unbiased metabolic profiling and data mining, metabolite annotation and biological interpretation.
A fully automated, high-throughput platform that quantitatively profiles microbial metabolome coupled with bioinformatics capable of integrating into metagenomics data to provide the functional translation of the microbiome.
Classification and prediction of disease phenotypes based on their unique metabolic signatures for patient stratification and personalized treatment.
