個(gè)人簡(jiǎn)介
姓名：郭曉奎
性別：男
出生年月：1964.9
學(xué)位/學(xué)歷：研究生/博士
職稱：教授
電子郵件：[email protected]
辦公地址：重慶南路280號(hào)1#409
辦公電話：021-63846590*776712
教育經(jīng)歷
（本科教育起）
1982年09月至1986年07月四川大學(xué)學(xué)習(xí)
1988年09月至1991年07月哈爾濱醫(yī)科大學(xué)學(xué)習(xí)
1997年09月至2000年07月日本愛(ài)知學(xué)院大學(xué)學(xué)習(xí)
工作經(jīng)歷
1986年08月2000年06月哈爾濱醫(yī)科大學(xué)工作
2000年07月至2019年06月上海交通大學(xué)醫(yī)學(xué)院基礎(chǔ)醫(yī)學(xué)院工作
2019年07月至今上海交通大學(xué)醫(yī)學(xué)院-國(guó)家熱帶病研究中心全球健康學(xué)院工作
社會(huì)/學(xué)術(shù)任職和活動(dòng)
中國(guó)微生物學(xué)會(huì)醫(yī)學(xué)微生物學(xué)與免疫學(xué)專業(yè)委員會(huì)主任委員,；
中華預(yù)防醫(yī)學(xué)會(huì)微生態(tài)學(xué)分會(huì) 副主任委員,；
中國(guó)微生物學(xué)會(huì)醫(yī)學(xué)細(xì)菌學(xué)學(xué)組 主任委員；
中國(guó)醫(yī)藥教育協(xié)會(huì)微生態(tài)學(xué)教育分會(huì) 副主任委員；
中國(guó)噬菌體診療聯(lián)盟 副理事長(zhǎng),；
上海市微生物學(xué)會(huì) 副理事長(zhǎng)、秘書(shū)長(zhǎng)
研究方向/主要研究?jī)?nèi)容
全健康科學(xué)研究,、細(xì)菌耐藥控制,、人獸共患病
科研/教學(xué)研究項(xiàng)目
時(shí)間：2022.01-01-2025.12.31 項(xiàng)目名稱：耐藥肺炎克雷伯菌對(duì)靶向保守受體噬菌體雞尾酒制劑的耐受突變機(jī)制及適應(yīng)性代價(jià)研究 項(xiàng)目編號(hào)：32170141 項(xiàng)目來(lái)源：國(guó)家自然科學(xué)基金面上項(xiàng)目
時(shí)間： 2021.07.01-2023.06.30 項(xiàng)目名稱：全健康：從領(lǐng)域到政策 項(xiàng)目編號(hào)：無(wú) 項(xiàng)目來(lái)源：美國(guó)中華醫(yī)學(xué)基金會(huì)（China Medical Board，CMB）
時(shí)間：2020.12-2021.12 項(xiàng)目名稱：中國(guó)經(jīng)驗(yàn)在阻斷湄公血吸蟲(chóng)病傳播中的適用性研究 項(xiàng)目編號(hào)：無(wú) 項(xiàng)目來(lái)源：2020年度上海交通大學(xué)“全球挑戰(zhàn)計(jì)劃”項(xiàng)目
時(shí)間：2016.01-2017.12 項(xiàng)目名稱：上海市公共衛(wèi)生三年行動(dòng)計(jì)劃重點(diǎn)學(xué)科建設(shè)項(xiàng)目傳染病與衛(wèi)生微生物學(xué) 項(xiàng)目編號(hào)：15GWZK0102 項(xiàng)目來(lái)源：上海市衛(wèi)計(jì)委
時(shí)間：2011.01-2015.12 項(xiàng)目名稱：自動(dòng)化臨床微生物分析檢測(cè)儀器的研制 項(xiàng)目編號(hào)：2011AA02A100 項(xiàng)目來(lái)源：科技部863重大項(xiàng)目
時(shí)間：2013.01-2016.12 項(xiàng)目名稱：不同動(dòng)物源性致病性鉤端螺旋體遺傳變異規(guī)律和致病差異的分子機(jī)制研究 項(xiàng)目編號(hào)：81271793 項(xiàng)目來(lái)源：國(guó)家自然科學(xué)基金面上項(xiàng)目
時(shí)間：2012.01-2015.12 項(xiàng)目名稱：基于Pan-genome技術(shù)探究問(wèn)號(hào)鉤端螺旋體不同血清型致病性差異的遺傳基礎(chǔ) 項(xiàng)目編號(hào)：81171587 項(xiàng)目來(lái)源：國(guó)家自然科學(xué)基金面上項(xiàng)目
時(shí)間：2012.01-2015.12 項(xiàng)目名稱：超級(jí)細(xì)菌的預(yù)警監(jiān)控和臨床防治綜合評(píng)價(jià)信息化平臺(tái)的建立（子課題） 項(xiàng)目編號(hào)：2012EP001004 項(xiàng)目來(lái)源：科技部支撐計(jì)劃
時(shí)間：2013.01-2015.12 項(xiàng)目名稱：鉤端螺旋體與宿主細(xì)胞相互作用及其分子致病機(jī)制的研究 項(xiàng)目編號(hào)：81261160321 項(xiàng)目來(lái)源：國(guó)家自然基金國(guó)際（地區(qū)）合作與交流項(xiàng)目
時(shí)間：2013.01-2015.12 項(xiàng)目名稱：不同動(dòng)物源性致病性鉤端螺旋體遺傳變異規(guī)律和致病差異的分子機(jī)制研究 項(xiàng)目編號(hào)：20120073110071 項(xiàng)目來(lái)源：高等學(xué)校博士學(xué)科點(diǎn)專項(xiàng)基金（博導(dǎo)類）
時(shí)間：2001.01-2003.12 項(xiàng)目名稱：鉤端螺旋體致病及免疫機(jī)理的功能基因組學(xué)研究 項(xiàng)目編號(hào)：2001AA223030 項(xiàng)目來(lái)源：科技部863計(jì)劃
時(shí)間：2004.01-2005.12 項(xiàng)目名稱：鉤端螺旋體致病及免疫機(jī)理的功能基因組學(xué)研究 項(xiàng)目編號(hào)：2003AA223030 項(xiàng)目來(lái)源：科技部863計(jì)劃
時(shí)間：2006.01-2008.12 項(xiàng)目名稱：鉤端螺旋體重要功能基因的發(fā)掘,、鑒定和應(yīng)用 項(xiàng)目編號(hào)：2006AA02Z176 項(xiàng)目來(lái)源：科技部863計(jì)劃
時(shí)間：2004.01-2006.12 項(xiàng)目名稱：鉤端螺旋體溶血素基因結(jié)構(gòu),、表達(dá)及功能的研究 項(xiàng)目編號(hào)：30670102 項(xiàng)目來(lái)源：國(guó)家自然科學(xué)基金面上項(xiàng)目
時(shí)間：2007.01-2009.12 項(xiàng)目名稱：鉤體血清型相關(guān)基因的研究 項(xiàng)目編號(hào)：30670102 項(xiàng)目來(lái)源：國(guó)家自然科學(xué)基金面上項(xiàng)目
時(shí)間：2008.01-2010.12 項(xiàng)目名稱：鉤端螺旋體比較蛋白質(zhì)組學(xué)研究 項(xiàng)目編號(hào)：30770111 項(xiàng)目來(lái)源：國(guó)家自然科學(xué)基金面上項(xiàng)目
時(shí)間：2008.01-2010.12 項(xiàng)目名稱：呼吸道感染和感染性腹瀉病原體診斷和組合檢測(cè)技術(shù) 項(xiàng)目編號(hào)：2008ZX10004-002 項(xiàng)目來(lái)源：十一五重大專項(xiàng)子課題
時(shí)間：2010.01-2011.12 項(xiàng)目名稱：重要人獸共患病鉤端螺旋體病通用疫苗的基礎(chǔ)研究 項(xiàng)目編號(hào)：10JC1408200 項(xiàng)目來(lái)源：上海市科委基礎(chǔ)研究重點(diǎn)項(xiàng)目
時(shí)間：2009.01-2010.12 項(xiàng)目名稱：鉤端螺旋體rel基因島致病機(jī)理研究 項(xiàng)目編號(hào)：09XD1402700 項(xiàng)目來(lái)源：上海市科委
主要學(xué)術(shù)成果
期刊論文
1. Huimin Li?, Yi Xie?, Fumin Chen, Huiwen Bai, Leshan Xiu, Xiaonong Zhou, Xiaokui Guo*, Qinqin Hu*and Kun Yin*. [Review] Amplification-free CRISPR/Cas Detection Technology: Challenges, Strategies, and Perspectives. Chemical Society Reviews 2023,52(1):361-382.
2. Yi Xie, Huimin Li, Fumin Chen, Srisruthi Udayakumar, Khyati Arora, Hui Chen, Yang Lan, Qinqin Hu, Xiaonong Zhou, Xiaokui Guo*, Leshan Xiu*, and Kun Yin*. [Review] Clustered Regularly Interspaced short palindromic repeats-Based Micro?uidic System in Infectious Diseases Diagnosis: Current Status, Challenges, and Perspectives. Advanced Science 2022, 2204172.
3. Hanqing Zhao, Siwei Fei, Jingxian Yin, Qin Li, Tiange Jiang, ZhaoYu Guo, Jingbo Xue, Lefei Han, Xiaoxi Zhang, Shang Xia, Yi Zhang, Xiaokui Guo and Kokouvi Kassegne*. Assessment of performance for a key indicator of One Health: evidence based on One Health index for zoonoses in Sub-Saharan Africa. Infect Dis Poverty 2022, 11:109.
4. Cheng Z, Zhou N, Zhang X, Lv C, Guo X, Zhu Y, Li M. Urging health collaboration to combat antimicrobial resistance between China and B&R countries. Infect Dis Poverty 2022, 11(1):108.
5. Zhang XX, Liu JS, Han LF, Simm G, Guo XK, Zhou XN*: One Health: new evaluation framework launched. Nature 2022, 604:625.
6. Chao Lv?, Jun Shang?, Wengang Zhang?, Bingqing Sun, Min Li1, Chaoyi Guo, Nan Zhou, Xiaokui Guo*, Shixin Huang* and Yongzhang Zhu*. Dynamic antimicrobial resistant patterns of Escherichia coli from healthy poultry and swine over 10 years in Chongming Island,Shanghai. Infectious Diseases of Poverty 2022, 11:98.
7. Zhang XX#, Liu JS#, Han LF, Xia S, Li S-Z, Li OY, Kassegne KK, Li M, Yin K, Hu QQ, Xiu LS, Zhu YY, Huang LY, Wang XC, Zhang Y, Zhao HQ, Yin JX, Jiang TG, Li Q, Fei SW, Gu SY, Chen FM, Zhou N, Cheng ZL, Xie Y, Li HM, Chen J, Guo ZY, Feng JX, Ai L, Xue JB, Ye Q, Grant L, Song JX, Simm G, Utzinger J, Guo XK*, Zhou XN*: Towards a global One Health index: a potential assessment tool for One Health performance. Infectious Diseases of Poverty 2022, 11:57.
8. Nan Zhou # , Zile Cheng # , Xiaoxi Zhang, Chao Lv, Chaoyi Guo, Haodong Liu, Ke Dong , Yan Zhang, Chang Liu , Yunfu Chang, Sheng Chen , Xiaokui Guo*, Xiao-Nong Zhou*, Min Li*, Yongzhang Zhu*. Global antimicrobial resistance: a system-wide comprehensive investigation using the Global One Health Index. Infectious Diseases of Poverty 2022, 11(1):92.
9. Zhu Y, Shi L, Zeng Y, Piao D, Xie Y, Du J, Gao M, Gao W, Tian J, Yue J, Li M, Guo X*, Yao Y*, Kang Y*. Key immunity characteristics of diverse stages of brucellosis in rural population from Inner Mongolia, China. Infect Dis Poverty 2022, 11(1):63.
10. Ping Lin, Junyu Sun, Xiaoyan Lou,Dan Li, Yun Shi, Zhenhua Li, Peijun Ma, Ping Li, Shuzi Chen, Weifeng Jin, Shuai Liu, Qing Chen, Qiong Gao, Lili Zhu, Jie Xu, Mengyuan Zhu, Mengxia Wang, Kangyi Liang, Ling Zhao, Huabin Xu, Ke Dong, Qingtian Li, Xunjia Cheng, Jinghong Chen*, Xiaokui Guo*. Consensus on potential biomarkers developed for use in clinical tests for schizophrenia. General Psychiatry 2022;35:e100685.
11. Miao L, Li H, Ding W, Lu S, Pan S, Guo X, Zhou X, Wang D. Research Priorities on One Health: A Bibliometric Analysis. Front Public Health 2022;10:889854.
12. Chang C, Yu X, Guo W, Guo C, Guo X*, Li Q*, Zhu Y*: Bacteriophage-Mediated Control of Biofilm: A Promising New Dawn for the Future. Front Microbiol 2022, 13:825828.
13. Cai M, Pu B, Wang Y, Lv L, Jiang C, Fu X, Zhang Y, Zhao W, Dong K, Yang Y, Liu Y, Wei Y, Zhang Z, Li J, Guo X, Liu C*, Qin J*: A Plasmid With Conserved Phage Genes Helps Klebsiella pneumoniae Defend Against the Invasion of Transferable DNA Elements at the Cost of Reduced Virulence. Front Microbiol 2022, 13:827545.
14. Jin LL, Deng L, Bartlett M, Ren YP, Lu JH, Chen Q, Pan YX, Wang H, Guo XK and Liu C*: A Novel Herbal Extract Blend Product Prevents Particulate Matters-Induced Inflammation by Improving Gut Microbiota and Maintaining the Integrity of the Intestinal Barrier. Nutrients 2022, 14(10): 2010.
15. Lin Lyu, Ru Feng, Mingnan Zhang, Qiyu Gong, Yinjing Liao, Yanjiao Zhou, Xiaokui Guo, Bing Su, Yair Dorsett*, Lei Chen*. Large scale sub-genomic RNA profiling suggests novel mechanism in coronavirus gene regulation and host adaption. Life Sci Alliance 2022, 5(8):e202101347.
16. Xiaomei Fu, Lin Lyu, Yue Wang, Yan Zhang, Xiaokui Guo, Qian Chen*, Chang Liu *. Safety assessment and probiotic characteristics of Enterococcus lactis JDM1. Microbial Pathogenesis 2022,163:105380.
17. Xinyu Feng, Sibao Wang, Gong Cheng, Xiaokui Guo and Xiaonong Zhou*. Editorial: Needs and potential application of One Health approach in the control of vector-borne and zoonotic infectious disease. Front Microbiol 2022, 13:1089174.
18. Liyuan Miao, Hao Li, Wei Ding, Shenning Lu, Shuning Pan, Xiaokui Guo, XiaoNong Zhou and Duoquan Wang*. Research Priorities on One Health: A Bibliometric Analysis. Front Microbiol 2022,10:889854.
19. Wang Y, Fan X, Du L, Liu B, Xiao H, Zhang Y, Wu Y, Liu F, Chang YF*, Guo X*, He P*: Scavenger receptor A1 participates in uptake of Leptospira interrogans serovar Autumnalis strain 56606v and inflammation in mouse macrophages. Emerging microbes & infections 2021:1-39.
20. Feng T, Leptihn S, Dong K, Loh B, Zhang Y, Stefan M, Li M, Guo X* and CuiZ*: JD419, a Staphylococcus aureus Phage With a Unique Morphology and Broad Host Range. Frontiers in microbiology 2021, 12:602902.
21. Wu N, Dai J, Guo M, Li J, Zhou X, Li F, Gao Y, Qu H, Lu H, Jin J, Li T, Shi L, Wu Q, Tan R, Zhu M, Yang L, Ling Y, Xing S, Zhang J, Yao B, Le S, Gu J, Qin J, Li J, Cheng M, Tan D, Li L, Zhang Y, Zhu Z, Cai J, Song Z, Guo X, Chen LK*, Zhu T*: Pre-optimized phage therapy on secondary Acinetobacter baumannii infection in four critical COVID-19 patients. Emerging microbes & infections 2021, 10:612-8.
22. Aman C, Wu Q, Lin L, Li H, Zhao L, Wen Z, Song Y, Wu Q, Wang J, Guo X, Wang H, Yu X, Wei D, Zhang S. Exosomal ncRNAs profiling of mycobacterial infection identified miRNA-185-5p as a novel biomarker for tuberculosis. Brief Bioinform 2021, bbab210.
23. Li T, Lyu L, Zhang Y, Dong K, Li Q*, Guo X*, Zhu Y*: A newly isolated E. thailandicus strain d5B with exclusively antimicrobial activity against C. difficile might be a novel therapy for controlling CDI. Genomics 2021, 113:475-83.
24. Qin J#, Wu N#, Bao J#, Shi X#, Ou H#, Ye S, Zhao W, Wei Z, Cai J, Li L, Guo M, Weng J, Lu H, Tan D, Zhang J, Huang Q, Zhu Z, Shi Y, Hu C, Guo X*, Zhu T*: Heterogeneous Klebsiella pneumoniae Co-infections Complicate Personalized Bacteriophage Therapy. Frontiers in cellular and infection microbiology 2021, 10:608402.
25. Li T, Lyu L, Zhang Y, Dong K, Li Q*, Guo X*, Zhu Y*: A newly isolated E. thailandicus strain d5B with exclusively antimicrobial activity against C. difficile might be a novel therapy for controlling CDI. Genomics 2021, 113:475-83.
26. Chen Q#, Ma X#, Li C, Shen Y, Zhu W, Zhang Y, Guo X, Zhou J*, Liu C*: Enteric Phageome Alterations in Patients With Type 2 Diabetes. Frontiers in cellular and infection microbiology 2020, 10:575084.
27. Wu C#, Du X#, Tang L#, Wu J, Zhao W, Guo X, Liu D, Hu W, Helmby H, Chen G*, Wang Z*: Schistosoma japonicum SjE16.7 Protein Promotes Tumor Development via the Receptor for Advanced Glycation End Products (RAGE). Frontiers in immunology 2020, 11:1767.
28. Tan D, Zhang Y, Qin J, Le S, Gu J, Chen LK, Guo X, Zhu T*: A Frame shift Mutation in wcaJ Associated with Phage Resistance in Klebsiella pneumoniae. Microorganisms 2020, 8.
29. Qin J#, Wu N#, Bao J#, Shi X#, Ou H#, Ye S, Zhao W, Wei Z, Cai J, Li L, Guo M, Weng J, Lu H, Tan D, Zhang J, Huang Q, Zhu Z, Shi Y, Hu C, Guo X*, Zhu T*: Heterogeneous Klebsiella pneumoniae Co-infections Complicate Personalized Bacteriophage Therapy. Frontiers in cellular and infection microbiology 2020, 10:608402.
30. Li T, Zhang Y, Dong K, Kuo CJ, Li C, Zhu YQ, Qin J, Li QT, Chang YF*, Guo X*, Zhu Y*: Isolation and Characterization of the Novel Phage JD032 and Global Transcriptomic Response during JD032 Infection of Clostridioides difficile Ribotype 078. mSystems 2020, 5.
31. Ji J, Liu Q, Wang R, Luo T, Guo X, Xu M, Yin Q, Wang X, Zhou M, Li M*, He P*: Identification of a novel phage targeting methicillin-resistant Staphylococcus aureus In vitro and In vivo. Microbial pathogenesis 2020, 149:104317.
32. Bao J#, Wu N#, Zeng Y#, Chen L#, Li L, Yang L, Zhang Y, Guo M, Li L, Li J, Tan D, Cheng M, Gu J, Qin J, Liu J, Li S, Pan G, Jin X, Yao B, Guo X, Zhu T*, Le S: Non-active antibiotic and bacteriophage synergism to successfully treat recurrent urinary tract infection caused by extensively drug-resistant Klebsiella pneumoniae. Emerging microbes & infections 2020, 9:771-4.
33. Zhang C#, Xu J#, Zhang T#, Qiu H, Li Z, Zhang E, Li S, Chang YF, Guo X, Jiang X*, Zhu Y*: Genetic characteristics of pathogenic Leptospira in wild small animals and livestock in Jiangxi Province, China, 2002-2015. PLoS neglected tropical diseases 2019, 13:e0007513.
34. Tan D, Zhang Y, Cheng M, Le S, Gu J, Bao J, Qin J, Guo X, Zhu T*: Characterization of Klebsiella pneumoniae ST11 Isolates and Their Interactions with Lytic Phages. Viruses 2019, 11.
35. Sun Y#, Chen Q#, Lin P#, Xu R#, He D, Ji W, Bian Y, Shen Y, Li Q, Liu C, Dong K, Tang YW, Pei Z, Yang L, Lu H, Guo X*, Xiao L*: Characteristics of Gut Microbiota in Patients With Rheumatoid Arthritis in Shanghai, China. Frontiers in cellular and infection microbiology 2019, 9:369.
36. Li XM#, Kang YX#, Lin L, Jia EH, Piao DR, Jiang H, Zhang CC, He J, Chang YF*, Guo XK*, Zhu Y*: Genomic Characterization Provides New Insights for Detailed Phage- Resistant Mechanism for Brucella abortus. Frontiers in microbiology 2019, 10:917.
37. Du X#, Zhang Y#, Li X, Li Q, Wu C, Chen G, Guo X, Weng Y*, Wang Z*: PRL2 serves as a negative regulator in cell adaptation to oxidative stress. Cell & bioscience 2019, 9:96.
38. Cui Z, Guo X, Feng T, Li L*: Exploring the whole standard operating procedure for phage therapy in clinical practice. Journal of translational medicine 2019, 17:373.
39. Zhu L, Luo F, Hu W, Han Y, Wang Y, Zheng H, Guo X*, Qin J*: Bacterial Communities in the Womb During Healthy Pregnancy. Frontiers in microbiology 2018, 9:2163.
40. Yin C#, Wu C#, Du X, Fang Y, Pu J, Wu J, Tang L, Zhao W, Weng Y, Guo X, Chen G*, Wang Z*: PRL2 Controls Phagocyte Bactericidal Activity by Sensing and Regulating ROS. Frontiers in immunology 2018, 9:2609.
41. Wei Y#, Yang F#, Wu Q, Gao J, Liu W, Liu C, Guo X, Suwal S, Kou Y, Zhang B, Wang Y, Zheng K*, Tang R*: Protective Effects of Bifidobacterial Strains Against Toxigenic Clostridium difficile. Frontiers in microbiology 2018, 9:888.
42. Wang J, Teng Z, Cui X, Li C, Pan H, Zheng Y, Mao S, Yang Y, Wu L, Guo X, Zhang X, Zhu Y: Epidemiological and serological surveillance of hand-foot-and-mouth disease in Shanghai, China, 2012-2016. Emerging microbes & infections 2018, 7:8.
43. Wang J#, Teng Z#, Chu W, Fang F, Cui X, Guo X, Zhang X*, Thorley BR*, Zhu Y*: The emergence and spread of one Coxsackievirus A16 Genogroup D novel recombinant strain that caused a clustering HFMD outbreak in Shanghai, China, 2016. Emerging microbes & infections 2018, 7:131.
44. Ding B, Li Q, Guo M, Dong K, Zhang Y, Guo X, Liu Q, Li L*, Cui Z*: Prevention of Dermal Abscess Formation Caused by Staphylococcus aureus Using Phage JD007 in Nude Mice. Frontiers in microbiology 2018, 9:1553.
45. Zhou K, Xie L, Han L, Guo X, Wang Y*, Sun J*: ICESag37, a Novel Integrative and Conjugative Element Carrying Antimicrobial Resistance Genes and Potential Virulence Factors in Streptococcus agalactiae. Frontiers in microbiology 2017, 8:1921.
46. Zhang F, Wang X, Xie L, Zheng Q, Guo X, Han L, Sun J*: A novel transposon, Tn6306, mediates the spread of blaIMI in Enterobacteriaceae in hospitals. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2017, 65:22-6.
47. Zeng L#, Wang D#, Hu N, Zhu Q, Chen K, Dong K, Zhang Y, Yao Y*, Guo X*, Chang YF*, Zhu Y*: A Novel Pan-Genome Reverse Vaccinology Approach Employing a Negative-Selection Strategy for Screening Surface-Exposed Antigens against leptospirosis. Frontiers in microbiology 2017, 8:396.
48. Xie L#, Dou Y#, Zhou K, Chen Y, Han L, Guo X, Sun J*: Coexistence of blaOXA-48 and Truncated blaNDM-1 on Different Plasmids in a Klebsiella pneumoniae Isolate in China. Frontiers in microbiology 2017, 8:133.
49. Xiao SZ, Wang S#, Wu WM#, Zhao SY, Gu FF, Ni YX, Guo XK, Qu JM*, Han LZ*: The Resistance Phenotype and Molecular Epidemiology of Klebsiella pneumoniae in Bloodstream Infections in Shanghai, China, 2012-2015. Frontiers in microbiology 2017, 8:250.
50. Xia B#, Sun L#, Fan X, Xiao H, Zhu Y, Qin J, Cai C, Zhao W, Chang YF, Zhang Y*, Guo X*, He P*: A new model of self-resolving leptospirosis in mice infected with a strain of Leptospira interrogans serovar Autumnalis harboring LPS signaling only through TLR4. Emerging microbes & infections 2017, 6:e36.
51. Wang S#, Xiao SZ#, Gu FF, Tang J, Guo XK, Ni YX, Qu JM*, Han LZ*: Antimicrobial susceptibility and molecular epidemiology of clinical Enterobacter cloacae bloodstream isolates in Shanghai, China. PloS one 2017, 12:e0189713.
52. Song Z#, Gu FF#, Guo XK, Ni YX, He P*, Han LZ*: Antimicrobial Resistance and Molecular Characterization of Staphylococcus aureus Causing Childhood Pneumonia in Shanghai. Frontiers in microbiology 2017, 8:455.
53. Lin P, Ding B, Feng C, Yin S, Zhang T, Qi X, Lv H, Guo X, Dong K, Zhu Y, Li Q*: Prevotella and Klebsiella proportions in fecal microbial communities are potential characteristic parameters for patients with major depressive disorder. Journal of affective disorders 2017, 207:300-4.
54. Hua Y#, Luo T#, Yang Y#, Dong D, Wang R, Wang Y, Xu M, Guo X, Hu F*, He P*: Phage Therapy as a Promising New Treatment for Lung Infection Caused by Carbapenem-Resistant Acinetobacter baumannii in Mice. Frontiers in microbiology 2017, 8:2659.
55. Guo M, Feng C, Ren J, Zhuang X, Zhang Y, Zhu Y, Dong K, He P, Guo X*, Qin J*: A Novel Antimicrobial Endolysin, LysPA26, against Pseudomonas aeruginosa. Frontiers in microbiology 2017, 8:293.
56. Cui Z, Guo X, Dong K, Zhang Y, Li Q, Zhu Y, Zeng L, Tang R, Li L*: Safety assessment of Staphylococcus phages of the family Myoviridae based on complete genome sequences. Scientific reports 2017, 7:41259.
57. Cui Z*#, Feng T#, Gu F, Li Q, Dong K, Zhang Y, Zhu Y, Han L, Qin J, Guo X*: Characterization and complete genome of the virulent Myoviridae phage JD007 active against a variety of Staphylococcus aureus isolates from different hospitals in Shanghai, China. Virology journal 2017, 14:26.
58. Chen Q, Ren Y, Lu J, Bartlett M, Chen L, Zhang Y, Guo X, Liu C*: A Novel Prebiotic Blend Product Prevents Irritable Bowel Syndrome in Mice by Improving Gut Microbiota and Modulating Immune Response. Nutrients 2017, 9.
59. Zhao SY#, Zhang J#, Zhang YL#, Wang YC, Xiao SZ, Gu FF, Guo XK, Ni YX, Han LZ*: Epidemiology and risk factors for faecal extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-E) carriage derived from residents of seven nursing homes in western Shanghai, China. Epidemiology and infection 2016, 144:695-702.
60. Zhang Q, Wan H, Huang S, Zhang Y, Wang Y, Guo X, He P*, Zhou M: Critical role of RIG-I-like receptors in inflammation in chronic obstructive pulmonary disease. The clinical respiratory journal 2016, 10:22-31.
61. Zhang F, Xie L, Wang X, Han L, Guo X, Ni Y, Qu H*, Sun J*: Further Spread of bla NDM-5 in Enterobacteriaceae via IncX3 Plasmids in Shanghai, China. Frontiers in microbiology 2016, 7:424.
62. Xu Y*, Zhu Y*, Wang Y*, Chang YF, Zhang Y, Jiang X, Zhuang X, Zhu Y, Zhang J, Zeng L, Yang M, Li S, Wang S, Ye Q, Xin X, Zhao G, Zheng H, Guo X, Wang J: Whole genome sequencing revealed host adaptation-focused genomic plasticity of pathogenic Leptospira. Scientific reports 2016, 6:20020.
63. Xie L, Wu J, Zhang F, Han L, Guo X, Ni Y, Sun J*: Molecular Epidemiology and Genetic Characteristics of Various blaPER Genes in Shanghai, China. Antimicrobial agents and chemotherapy 2016, 60:3849-53.
64. Wei Y#, Ye L#, Li Y, Yang F, Liu D, Guo X, Tang R*, Liu C*: Functional characterization of RelBE toxin-antitoxin system in probiotic Bifidobacterium longum JDM301. Acta biochimica et biophysica Sinica 2016, 48:741-9.
65. Wang Y, Li R, Zhou Y, Ling Z, Guo X, Xie L, Liu L*: Motif-Based Text Mining of Microbial Metagenome Redundancy Profiling Data for Disease Classification. BioMed research international 2016, 2016:6598307.
66. Wang Y, Ding X, Chen Y, Guo M, Zhang Y, Guo X*, Gu H*: Antibiotic-loaded, silver core-embedded mesoporous silica nanovehicles as a synergistic antibacterial agent for the treatment of drug-resistant infections. Biomaterials 2016, 101:207-16.
67. Wang S#, Zhao SY#, Xiao SZ, Gu FF, Liu QZ, Tang J, Guo XK, Ni YX, Han LZ*: Antimicrobial Resistance and Molecular Epidemiology of Escherichia coli Causing Bloodstream Infections in Three Hospitals in Shanghai, China. PloS one 2016, 11:e0147740.
68. Shi SF, Jia JF, Guo XK, Zhao YP, Chen DS, Guo YY, Zhang XL*: Reduced Staphylococcus aureus biofilm formation in the presence of chitosan-coated iron oxide nanoparticles. International journal of nanomedicine 2016, 11:6499-506.
69. Gu FF, Zhang J, Zhao SY, Yang ZR, Zhang YL, Xiao SZ, Wang S, Guo XK, Qu JM, Ni YX, Han LZ*: Risk factors for methicillin-resistant Staphylococcus aureus carriage among residents in 7 nursing homes in Shanghai, China. American journal of infection control 2016, 44:805-8.
70. Gu FF#, Chen Y#, Dong DP, Song Z, Guo XK, Ni YX, Han LZ*: Molecular Epidemiology of Staphylococcus aureus among Patients with Skin and Soft Tissue Infections in Two Chinese Hospitals. Chinese medical journal 2016, 129:2319-24.
71. Zhu W, Wang J, Zhu Y, Tang B, Zhang Y, He P, Zhang Y, Liu B, Guo X*, Zhao G*, Qin J*: Identification of three extra-chromosomal replicons in Leptospira pathogenic strain and development of new shuttle vectors. BMC genomics 2015, 16:90.
72. Zhou Y, Lin F, Cui Z, Zhang X, Hu C, Shen T, Chen C, Zhang X*, Guo X*: Correlation between Either Cupriavidus or Porphyromonas and Primary Pulmonary Tuberculosis Found by Analysing the Microbiota in Patients' Bronchoalveolar Lavage Fluid. PloS one 2015, 10:e0124194.
73. Zhao SY, Wang YC, Xiao SZ, Jiang XF, Guo XK, Ni YX, Han LZ*: Drug susceptibility and molecular epidemiology of Escherichia coli in bloodstream infections in Shanghai, China, 2011-2013. Infectious diseases 2015, 47:310-8.
74. Zhang Y, Sun J, Mi C, Li W, Zhao S, Wang Q, Shi D, Liu L, Ding B, Chang YF, Guo H*, Guo X, Li Q*, Zhu Y*: First report of two rapid-onset fatal infections caused by a newly emerging hypervirulent K. Pneumonia ST86 strain of serotype K2 in China. Frontiers in microbiology 2015, 6:721.
75. Zhang J#, Gu FF#, Zhao SY, Xiao SZ, Wang YC, Guo XK, Ni YX, Han LZ*: Prevalence and Molecular Epidemiology of Staphylococcus aureus among Residents of Seven Nursing Homes in Shanghai. PloS one 2015, 10:e0137593.
76. Zhang C, Yang H, Li X, Cao Z, Zhou H, Zeng L, Xu J, Xu Y, Chang YF, Guo X*, Zhu Y*, Jiang X*: Molecular Typing of Pathogenic Leptospira Serogroup Icterohaemorrhagiae Strains Circulating in China during the Past 50 Years. PLoS neglected tropical diseases 2015, 9:e0003762.
77. Zeng LB#, Zhuang XR#, Huang LL, Zhang YY, Chen CY, Dong K, Zhang Y, Cui ZL, Ding XL, Chang YF*, Guo XK*, Zhu YZ*: Comparative subproteome analysis of three representative Leptospira interrogans vaccine strains reveals cross-reactive antigens and novel virulence determinants. Journal of proteomics 2015, 112:27-37.
78. Wei YX#, Ye L#, Liu DB, Zhang ZY, Liu C*, Guo XK*: Activation of the chromosomally encoded mazEF(Bif) locus of Bifidobacterium longum under acid stress. International journal of food microbiology 2015, 207:16-22.
79. Wang Y, Zhuang X, Zhong Y, Zhang C, Zhang Y, Zeng L, Zhu Y, He P, Dong K, Pal U*, Guo X*, Qin J*: Distribution of Plasmids in Distinct Leptospira Pathogenic Species. PLoS neglected tropical diseases 2015, 9:e0004220.
80. Wang XF#, Tian F#, Cao RM, Li J, Wu SM, Guo XK*, Chen TX*: Antimicrobial activity of human beta-defensins against lactic acid bacteria. Natural product research 2015, 29:2164-6.
81. Scaria J#, Suzuki H#, Ptak CP, Chen JW, Zhu Y, Guo XK, Chang YF: Comparative genomic and phenomic analysis of Clostridium difficile and Clostridium sordellii, two related pathogens with differing host tissue preference. BMC genomics 2015, 16:448.
82. Kang YX, Li XM, Piao DR, Tian GZ, Jiang H, Jia EH, Lin L, Cui BY*, Chang YF*, Guo XK*, Zhu YZ*: Typing Discrepancy Between Phenotypic and Molecular Characterization Revealing an Emerging Biovar 9 Variant of Smooth Phage-Resistant B. abortus Strain 8416 in China. Frontiers in microbiology 2015, 6:1375.
83. Gu FF#, Hou Q#, Yang HH, Zhu YQ, Guo XK, Ni YX, Han LZ*: Characterization of Staphylococcus aureus Isolated from Non-Native Patients with Skin and Soft Tissue Infections in Shanghai. PloS one 2015, 10:e0123557.
84. Fang Y#, Wu C#, Chen Q, Wu J, Yang Y, Guo X, Chen G*, Wang Z*: SjE16.7 activates macrophages and promotes Schistosoma japonicum egg-induced granuloma development. Acta tropica 2015, 149:49-58.
85. Fan J, Zhang Y, Xiong H, Wang Y, Guo X*: Nucleotide analogue-resistant mutations in hepatitis B viral genomes found in hepatitis B patients. The Journal of general virology 2015, 96:663-70.
86. Zhu WN#, Huang LL#, Zeng LB, Zhuang XR, Chen CY, Wang YZ, Qin JH, Zhu YZ, Guo XK*: Isolation and characterization of two novel plasmids from pathogenic Leptospira interrogans serogroup Canicola Serovar Canicola strain Gui44. PLoS neglected tropical diseases 2014, 8:e3103.
87. Zhao JW, Sun ZQ, Zhang XY, Zhang Y, Liu J, Ye J, Chen CC, Samten B, Wang HH, Guo XK*, Zhang SL*: Mycobacterial 3-hydroxyacyl-l-thioester dehydratase Y derived from Mycobacterium tuberculosis induces COX-2 expression in mouse macrophages through MAPK-NF-kappaB pathway. Immunology letters 2014, 161:125-32.
88. Yuan L, Cui Z, Wang Y, Guo X*, Zhao Y*: Complete genome sequence of virulent bacteriophage SHOU24, which infects foodborne pathogenic Vibrio parahaemolyticus. Archives of virology 2014, 159:3089-93.
89. Yu XL, Wen ZL, Chen GZ, Li R, Ding BB, Yao YF, Li Y, Wu H, Guo XK, Wang HH, Zhang SL*: Molecular characterization of multidrug-resistant Mycobacterium tuberculosis isolated from south-central in China. The Journal of antibiotics 2014, 67:291-7.
90. Wu J, Lin K, Zeng J, Liu W, Yang F, Wang X, Xiao Y, Guo X, Nie H, Zhou T, Xu C*: Role of DC-SIGN in Helicobacter pylori infection of gastrointestinal cells. Frontiers in bioscience 2014, 19:825-34.
91. Wu J, Lin K, Zeng J, Liu W, Yang F, Wang X, Xiao Y, Guo X, Nie H, Zhou T, Xu C*: Role of DC-SIGN in Helicobacter pylori infection of gastrointestinal cells. Frontiers in bioscience 2014, 19:825-34.
92. Wu C#, Chen Q#, Fang Y, Wu J, Han Y, Wang Y, Yang Y, Chu M, Feng Y, Tan L, Guo X, Hu W, Wang Z*: Schistosoma japonicum egg specific protein SjE16.7 recruits neutrophils and induces inflammatory hepatic granuloma initiation. PLoS neglected tropical diseases 2014, 8:e2703.
93. Wang YL, Qin JH, Zhang CC, Guo XK, Jiang XG*, He P*: An outbreak of leptospirosis in Lezhi County, China in 2010 may possibly be linked to rainfall. Biomedical and environmental sciences : BES 2014, 27:56-9.
94. Wang Y, Zhao S, Han L, Guo X, Chen M, Ni Y, Zhang Y, Cui Z, He P*: Drug resistance and virulence of uropathogenic Escherichia coli from Shanghai, China. The Journal of antibiotics 2014, 67:799-805.
95. Liu B*, Wang Y*, Guo X*, Zhu W*, Zhang Y*, He P*: Carboxyfluorescein diacetate succinimidyl ester labeling method to study the interaction between Leptospira and macrophages. Journal of microbiological methods 2014, 107:205-13.
96. Huang L#, Zhu W#, He P, Zhang Y, Zhuang X, Zhao G, Guo X, Qin J*, Zhu Y*: Re-characterization of an extrachromosomal circular plasmid in the pathogenic Leptospira interrogans serovar Lai strain 56601. Acta biochimica et biophysica Sinica 2014, 46:605-11.
97. Fan J, Wang Y, Xiong H, Guo X*, Cheng YC*: Impact of the rtI187V polymerase substitution of hepatitis B virus on viral replication and antiviral drug susceptibility. The Journal of general virology 2014, 95:2523-30.
98. Zhao J, Sun Z, Pei H, Ye J, Chen C, Samten B, Zhang S*, Guo X*: Immunological evaluation of a novel Mycobacterium tuberculosis antigen, Rv3117, absent in Mycobacterium bovis BCG. Molecular medicine reports 2013, 8:1587-93.
99. Zhang ZY#*, Sun ZQ#, Wang ZL, Hu HR, Wen ZL, Song YZ, Zhao JW, Wang HH, Guo XK, Zhang SL: Identification and pathogenicity analysis of a novel non-tuberculous mycobacterium clinical isolate with nine-antibiotic resistance. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2013, 19:91-6.
100. Zhang Y, Dong K, Zeng L, Li Q, Liu C, Wang J, Guo X*, Zhao GP*: Genetic and molecular biological characterization of two homologous cheR genes from Leptospira interrogans. Acta biochimica et biophysica Sinica 2013, 45:806-16.
101. Zeng L#, Zhang Y#, Zhu Y, Yin H, Zhuang X, Zhu W, Guo X*, Qin J*: Extracellular proteome analysis of Leptospira interrogans serovar Lai. Omics : a journal of integrative biology 2013, 17:527-35.
102. Kang Y, Jia E, Lin L, Duan X, Xiao P, Peng J, Gao W, Zhang C, Guo X*, Cui B*, Li X*: Simultaneous emergence of several biotypes of Brucella among Baotou's brucellosis patients by combined diagnostic strategy. Acta biochimica et biophysica Sinica 2013, 45:893-5.
103. He P, Deng C, Liu B, Zeng L, Zhao W, Zhang Y, Jiang X, Guo X, Qin J*: Characterization of a bifunctional enzyme with (p)ppGpp-hydrolase/synthase activity in Leptospira interrogans. FEMS microbiology letters 2013, 348:133-42.
104. Gong L, Han Y, Chen L, Liu F, Hao P, Sheng J, Li XH, Yu DM, Gong QM, Tian F, Guo XK, Zhang XX*: Comparison of next-generation sequencing and clone-based sequencing in analysis of hepatitis B virus reverse transcriptase quasispecies heterogeneity. Journal of clinical microbiology 2013, 51:4087-94.
105. Chen C, Shen T, Tian F, Lin P, Li Q, Cui Z, Zhang Y, Xue M, Ye J, Guo X, Zhou Y*: New microbiota found in sputum from patients with community-acquired pneumonia. Acta biochimica et biophysica Sinica 2013, 45:1039-48.
106. Zhou Y, Tao J, Yu H, Ni J, Zeng L, Teng Q, Kim KS, Zhao GP, Guo X*, Yao Y*: Hcp family proteins secreted via the type VI secretion system coordinately regulate Escherichia coli K1 interaction with human brain microvascular endothelial cells. Infection and immunity 2012, 80:1243-51.
107. Zheng LL, Li YX, Ding J, Guo XK, Feng KY, Wang YJ, Hu LL, Cai YD*, Hao P*, Chou KC: A comparison of computational methods for identifying virulence factors. PloS one 2012, 7:e42517.
108. Zhang ZY, Liu C, Zhu YZ, Wei YX, Tian F, Zhao GP, Guo XK*: Safety assessment of Lactobacillus plantarum JDM1 based on the complete genome. International journal of food microbiology 2012, 153:166-70.
109. Zhang Y#, Lou XL#, Yang HL, Guo XK, Zhang XY, He P*, Jiang XC*: Establishment of a leptospirosis model in guinea pigs using an epicutaneous inoculations route. BMC infectious diseases 2012, 12:20.
110. Zhang MM, Zhao JW, Sun ZQ, Liu J, Guo XK, Liu WD*, Zhang SL*: Identification of RD5-encoded Mycobacterium tuberculosis proteins as B-cell antigens used for serodiagnosis of tuberculosis. Clinical & developmental immunology 2012, 2012:738043.
111. Wei YX, Zhang ZY, Liu C, Malakar PK, Guo XK*: Safety assessment of Bifidobacterium longum JDM301 based on complete genome sequences. World journal of gastroenterology 2012, 18:479-88.
112. Wang Y, Zhou Y, Li Y, Ling Z, Zhu Y, Guo X*, Sun H*: An improved dimensionality reduction method for meta-transcriptome indexing based diseases classification. BMC systems biology 2012, 6 Suppl 3:S12.
113. Shi SF, Jia JF, Guo XK, Zhao YP, Chen DS, Guo YY, Cheng T, Zhang XL*: Biocompatibility of chitosan-coated iron oxide nanoparticles with osteoblast cells. International journal of nanomedicine 2012, 7:5593-602.
114. Peng N, Zhong Y, Zhang Q, Zheng M, Zhao W, Jiang H, Yang C, Guo X, Zhao G*: Characterization of acetyl-CoA and propionyl-CoA carboxylases encoded by Leptospira interrogans serovar Lai: an initial biochemical study for leptospiral gluconeogenesis via anaplerotic CO(2) assimilation. Acta biochimica et biophysica Sinica 2012, 44:692-702.
115. Li Q, Huang J, Guo H, Guo X, Zhu Y*, Dong K*: Bactericidal activity against meticillin-resistant Staphylococcus aureus of a novel eukaryotic therapeutic recombinant antimicrobial peptide. International journal of antimicrobial agents 2012, 39:496-9.
116. Cui Z, Zhou Y, Li H, Zhang Y, Zhang S, Tang S*, Guo X*: Complex sputum microbial composition in patients with pulmonary tuberculosis. BMC microbiology 2012, 12:276.
117. Cui Z, Song Z, Wang Y, Zeng L, Shen W, Wang Z, Li Q, He P, Qin J*, Guo X*: Complete genome sequence of wide-host-range Staphylococcus aureus phage JD007. Journal of virology 2012, 86:13880-1.
118. Cui Z, Shen W, Wang Z, Zhang H, Me R, Wang Y, Zeng L, Zhu Y, Qin J, He P*, Guo X*: Complete genome sequence of Klebsiella pneumoniae phage JD001. Journal of virology 2012, 86:13843.
119. Zhong Y*, Chang X*, Cao XJ*, Zhang Y, Zheng H, Zhu Y, Cai C, Cui Z, Zhang Y, Li YY, Jiang XG, Zhao GP, Wang S*, Li Y*, Zeng R*, Li X*, Guo XK*: Comparative proteogenomic analysis of the Leptospira interrogans virulence-attenuated strain IPAV against the pathogenic strain 56601. Cell research 2011, 21:1210-29.
120. Zhang ZY, Sun ZQ, Wang ZL, Wen ZL, Sun QW, Zhu ZQ, Song YZ, Zhao JW, Wang HH#, Zhang SL#*, Guo XK#*: Complete genome sequence of a novel clinical isolate, the nontuberculous Mycobacterium strain JDM601. Journal of bacteriology 2011, 193:4300-1.
121. Zhang SM*, Tian F*, Huang QF, Zhao YF, Guo XK, Zhang FQ: Bacterial diversity of subgingival plaque in 6 healthy Chinese individuals. Experimental and therapeutic medicine 2011, 2:1023-9.
122. Zhang SM*, Tian F*, Huang QF, Zhao YF, Guo XK, Zhang FQ: Bacterial diversity of subgingival plaque in 6 healthy Chinese individuals. Experimental and therapeutic medicine 2011, 2:1023-9.
123. Zhang Q, Zhang Y, Zhong Y, Ma J, Peng N, Cao X, Yang C, Zeng R, Guo X, Zhao G*: Leptospira interrogans encodes an ROK family glucokinase involved in a cryptic glucose utilization pathway. Acta biochimica et biophysica Sinica 2011, 43:618-29.
124. Yalin W, Lingbing Z, Hongliang Y, Jianmin X, Xiangyan Z, Xiaokui G, Utpal P, Jinhong Q*: High prevalence of pathogenic Leptospira in wild and domesticated animals in an endemic area of China. Asian Pacific journal of tropical medicine 2011, 4:841-5.
125. Ning RD, Zhang XL*, Li QT, Guo XK: The effect of Staphylococcus aureus on apoptosis of cultured human osteoblasts. Orthopaedic surgery 2011, 3:199-204.
126. Ning R, Zhang X*, Guo X, Li Q: Staphylococcus aureus regulates secretion of interleukin-6 and monocyte chemoattractant protein-1 through activation of nuclear factor kappaB signaling pathway in human osteoblasts. The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 2011, 15:189-94.
127. Cheng Z, Zhao JW, Sun ZQ, Song YZ, Sun QW, Zhang XY, Zhang XL, Wang HH, Guo XK, Liu YF*, Zhang SL*: Evaluation of a novel fusion protein antigen for rapid serodiagnosis of tuberculosis. Journal of clinical laboratory analysis 2011, 25:344-9.
128. Zhu YZ#, Cai CS#, Zhang W, Guo HX, Zhang JP, Ji YY, Ma GY, Wu JL, Li QT, Lu CP, Guo XK*: Immunoproteomic analysis of human serological antibody responses to vaccination with whole-cell pertussis vaccine (WCV). PloS one 2010, 5:e13915.
129. Zhou Y, Lin P, Li Q, Han L, Zheng H, Wei Y, Cui Z, Ni Y, Guo X*: Analysis of the microbiota of sputum samples from patients with lower respiratory tract infections. Acta biochimica et biophysica Sinica 2010, 42:754-61.
130. Yang J#, Xu J#, Chen X#, Zhang Y, Jiang X, Guo X, Zhao G*: Decrease of plasma platelet-activating factor acetylhydrolase activity in lipopolysaccharide induced mongolian gerbil sepsis model. PloS one 2010, 5:e9190.
131. Wu CY*, Feng Y*, Qian GC#, Wu JH*, Luo J#, Wang Y, Chen GJ, Guo XK*, Wang ZJ*: alpha-Galactosylceramide protects mice from lethal Coxsackievirus B3 infection and subsequent myocarditis. Clinical and experimental immunology 2010, 162:178-87.
132. Wei YX, Zhang ZY, Liu C, Zhu YZ, Zhu YQ, Zheng H, Zhao GP, Wang S, Guo XK*: Complete genome sequence of Bifidobacterium longum JDM301. Journal of bacteriology 2010, 192:4076-7.
133. Ning R, Zhang X*, Guo X, Li Q: Attachment of Staphylococcus aureus is required for activation of nuclear factor kappa B in human osteoblasts. Acta biochimica et biophysica Sinica 2010, 42:883-92.
134. Liu C, Zhang ZY, Dong K, Guo XK*: Adhesion and immunomodulatory effects of Bifidobacterium lactis HN019 on intestinal epithelial cells INT-407. World journal of gastroenterology 2010, 16:2283-90.
135. Dong K#, Li Q#, Liu C, Zhang Y, Zhao G, Guo X*: Cloning and characterization of three cheB genes in Leptospira interrogans. Acta biochimica et biophysica Sinica 2010, 42:216-23.
136. Cao XJ, Dai J, Xu H, Nie S, Chang X, Hu BY, Sheng QH, Wang LS, Ning ZB, Li YX, Guo XK, Zhao GP*, Zeng R*: High-coverage proteome analysis reveals the first insight of protein modification systems in the pathogenic spirochete Leptospira interrogans. Cell research 2010, 20:197-210.
137. Cai CS#, Zhu YZ#, Zhong Y, Xin XF, Jiang XG, Lou XL, He P, Qin JH, Zhao GP, Wang SY*, Guo XK*: Development of O-antigen gene cluster-specific PCRs for rapid typing six epidemic serogroups of Leptospira in China. BMC microbiology 2010, 10:67.
138. Zhao W, Chen CY, Zhang XY, Lai WQ, Hu BY, Zhao GP, Qin JH*, Guo XK*: Molecular characterization of the pL40 protein in Leptospira interrogans. Canadian journal of microbiology 2009, 55:739-49.
139. Zhang ZY, Liu C, Zhu YZ, Zhong Y, Zhu YQ, Zheng HJ, Zhao GP, Wang SY, Guo XK*: Complete genome sequence of Lactobacillus plantarum JDM1. Journal of bacteriology 2009, 191:5020-1.
140. Zhang SM*, Tian F#, Jiang XQ#*, Li J*, Xu C*, Guo XK#, Zhang FQ*: Evidence for calcifying nanoparticles in gingival crevicular fluid and dental calculus in periodontitis. Journal of periodontology 2009, 80:1462-70.
141. Yuan J*, Li P, Tao J, Shi X, Hu B, Chen H, Guo X*: H. pylori escape host immunoreaction through inhibiting ILK expression by VacA. Cellular & molecular immunology 2009, 6:191-7.
142. Yao Y, Xie Y, Perace D, Zhong Y, Lu J, Tao J, Guo X, Kim KS*: The type III secretion system is involved in the invasion and intracellular survival of Escherichia coli K1 in human brain microvascular endothelial cells. FEMS microbiology letters 2009, 300:18-24.
143. Yang R*, Guo X, Yang J, Jiang Y, Pang B, Chen C, Yao Y, Qin J, Li Q: Genomic research for important pathogenic bacteria in China. Science in China Series C, Life sciences 2009, 52:50-63.
144. Yang J#, Zhang Y#, Xu J, Geng Y, Chen X, Yang H, Wang S, Wang H, Jiang X, Guo X, Zhao G*: Serum activity of platelet-activating factor acetylhydrolase is a potential clinical marker for leptospirosis pulmonary hemorrhage. PloS one 2009, 4:e4181.
145. Lu Q#, Yu DH#, Fang C, Liu F, Ye X, Zhao Y, Qin J, Guo XK, Liang M, Hu F, Chen HZ*: Influence of E3 region on conditionally replicative adenovirus mediated cytotoxicity in hepatocellular carcinoma cells. Cancer biology & therapy 2009, 8:1125-32.
146. Liu C, Zhang ZY, Dong K, Yuan JP, Guo XK*: Antibiotic resistance of probiotic strains of lactic acid bacteria isolated from marketed foods and drugs. Biomedical and environmental sciences : BES 2009, 22:401-12.
147. Feng CY, Li QT*, Zhang XY, Dong K, Hu BY, Guo XK: Immune strategies using single-component LipL32 and multi-component recombinant LipL32-41-OmpL1 vaccines against leptospira. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2009, 42:796-803.
148. Zhu YZ*, Li QT*, Wang L, Zhong Y, Ding GH, Li G, Jia PL, Shi TL, Guo XK: Gene expression profiling-based in silico approach to identify potential vaccine candidates and drug targets against B. pertussis and B. parapertussis. Omics : a journal of integrative biology 2008, 12:161-9.
149. Zhang YX#, Geng Y#, Yang JW, Guo XK, Zhao GP*: Cytotoxic activity and probable apoptotic effect of Sph2, a sphigomyelinase hemolysin from Leptospira interrogans strain Lai. BMB reports 2008, 41:119-25.
150. Qin JH#, Zhang Q#, Zhang ZM, Zhong Y, Yang Y, Hu BY, Zhao GP*, Guo XK*: Identification of a novel prophage-like gene cluster actively expressed in both virulent and avirulent strains of Leptospira interrogans serovar Lai. Infection and immunity 2008, 76:2411-9.
151. Zou Y, Guo X, Picardeau M, Xu H, Zhao G*: A comprehensive survey on isoleucine biosynthesis pathways in seven epidemic Leptospira interrogans reference strains of China. FEMS microbiology letters 2007, 269:90-6.
152. He P#, Sheng YY#, Shi YZ, Jiang XG, Qin JH, Zhang ZM, Zhao GP*, Guo XK*: Genetic diversity among major endemic strains of Leptospira interrogans in China. BMC genomics 2007, 8:204.
153. Yang HL, Zhu YZ, Qin JH, He P, Jiang XC, Zhao GP*, Guo XK*: In silico and microarray-based genomic approaches to identifying potential vaccine candidates against Leptospira interrogans. BMC genomics 2006, 7:293.
154. Yang HL, Jiang XC*, Zhang XY, Li WJ, Hu BY, Zhao GP, Guo XK*: Thrombocytopenia in the experimental leptospirosis of guinea pig is not related to disseminated intravascular coagulation. BMC infectious diseases 2006, 6:19.
155. Qin JH, Sheng YY, Zhang ZM, Shi YZ, He P, Hu BY, Yang Y, Liu SG, Zhao GP*, Guo XK*: Genome-wide transcriptional analysis of temperature shift in L. interrogans serovar lai strain 56601. BMC microbiology 2006, 6:51.
156. Li ZH#, Dong K#, Yuan JP, Hu BY, Liu JX, Zhao GP*, Guo XK*: Characterization of the cheY genes from Leptospira interrogans and their effects on the behavior of Escherichia coli. Biochemical and biophysical research communications 2006, 345:858-66.
157. Li ZH, Dong K, Sun JC, Yuan JP, Hu BY, Liu JX, Zhao GP*, Guo XK*: Characterization of cheW genes of Leptospira interrogans and their effects in Escherichia coli. Acta biochimica et biophysica Sinica 2006, 38:79-88.
158. Li QT#, Zhu YZ#, Chu JY*, Dong K, He P, Feng CY, Hu BY, Zhang SM, Guo XK*: Granulocyte-macrophage colony-stimulating factor DNA prime-protein boost strategy to enhance efficacy of a recombinant pertussis DNA vaccine. Acta pharmacologica Sinica 2006, 27:1487-94.
159. Li Q#, Zhu Y#, Chu J, Wang Y, Xu Y, Hou Q, Zhang S, Guo X*: Protective immunity against Bordetella pertussis by a recombinant DNA vaccine and the effect of coinjection with a granulocyte-macrophage colony stimulating factor gene. Microbiology and immunology 2006, 50:929-36.
160. Guo XK, Zhao WQ, Kondo C, Shimojo N, Yamashita K, Aoki T, Hayakawa T*: Tissue inhibitors of metalloproteinases-1 (TIMP-1) and -2(TIMP-2) are major serum factors that stimulate the TIMP-1 gene in human gingival fibroblasts. Biochimica et biophysica acta 2006, 1763:296-304.
161. Zhang YX#, Geng Y#, Bi B, He JY, Wu CF, Guo XK, Zhao GP*: Identification and classification of all potential hemolysin encoding genes and their products from Leptospira interrogans serogroup Icterohae-morrhagiae serovar Lai. Acta pharmacologica Sinica 2005, 26:453-61.
162. Zhang XY#, Yu Y#, He P, Zhang YX, Hu BY, Yang Y, Nie YX, Jiang XG, Zhao GP, Guo XK*: Expression and comparative analysis of genes encoding outer membrane proteins LipL21, LipL32 and OmpL1 in epidemic leptospires. Acta biochimica et biophysica Sinica 2005, 37:649-56.
163. Wang HT, Li ZH, Yuan JP, Zhao W, Shi XD, Tong SQ, Guo XK*: Effect of Helicobacter pylori VacA on gene expression of gastric cancer cells. World journal of gastroenterology 2005, 11:109-13.
164. Zhang YX, Li J, Guo XK, Wu C, Bi B, Ren SX, Wu CF, Zhao GP*: Characterization of a novel toxin-antitoxin module, VapBC, encoded by Leptospira interrogans chromosome. Cell research 2004, 14:208-16.
165. Yuan JP, Li T, Li ZH, Yang GZ, Hu BY, Shi XD, Shi TL, Tong SQ, Guo XK*: mRNA expression profiling reveals a role of Helicobacter pylori vacuolating toxin in escaping host defense. World journal of gastroenterology 2004, 10:1528-32.
166. Yuan JP, Li T, Chen HB, Li ZH, Yang GZ, Hu BY, Shi XD, Tong SQ, Li YX, Guo XK*: Analysis of gene expression profile in gastric cancer cells stimulated with Helicobacter pylori isogenic strains. Journal of medical microbiology 2004, 53:965-74.
167. Xu H, Zhang Y, Guo X, Ren S, Staempfli AA, Chiao J, Jiang W, Zhao G*: Isoleucine biosynthesis in Leptospira interrogans serotype lai strain 56601 proceeds via a threonine-independent pathway. Journal of bacteriology 2004, 186:5400-9.
168. Li ZH, Nie BM, Chen H, Chen SY, He P, Lu Y, Guo XK, Liu JX*: In vitro anti-coxsackievirus B(3) effect of ethyl acetate extract of Tian-hua-fen. World journal of gastroenterology 2004, 10:2263-6.
169. He P, Zhang XY, Guo XK*, Hu BY, Huang XT, Yang Y, Zhao GP*: Identification and analysis of genes present in Leptospira interrogans serovar lai but absent in L. biflexa serovar monvalerio. Acta biochimica et biophysica Sinica 2004, 36:832-9.
170. Yuan JP, Zhao W, Wang HT, Wu KY, Li T, Guo XK*, Tong SQ: Coxsackievirus B3-induced apoptosis and caspase-3. Cell research 2003, 13:203-9.
171. Yuan JP, Li T, Shi XD, Hu BY, Yang GZ, Tong SQ, Guo XK*: Deletion of Helicobacter pylori vacuolating cytotoxin gene by introduction of directed mutagenesis. World journal of gastroenterology 2003, 9:2251-7.
172. Ren SX#, Fu G#, Jiang XG#, Zeng R#, Miao YG, Xu H, Zhang YX, Xiong H, Lu G, Lu LF, Jiang HQ, Jia J, Tu YF, Jiang JX, Gu WY, Zhang YQ, Cai Z, Sheng HH, Yin HF, Zhang Y, Zhu GF, Wan M, Huang HL, Qian Z, Wang SY, Ma W, Yao ZJ, Shen Y, Qiang BQ, Xia QC, Guo XK, Danchin A, Saint Girons I, Somerville RL, Wen YM, Shi MH, Chen Z, Xu JG, Zhao GP*: Unique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing. Nature 2003, 422:888-93.
173. Zhao WQ, Li H, Yamashita K, Guo XK, Hoshino T, Yoshida S, Shinya T, Hayakawa T*: Cell cycle-associated accumulation of tissue inhibitor of metalloproteinases-1 (TIMP-1) in the nuclei of human gingival fibroblasts. Journal of cell science 1998, 111 ( Pt 9):1147-53.
著作
主編《全健康科技進(jìn)展2021》，科學(xué)出版社,，2022
主編《全健康科技進(jìn)展》,，上海交通大學(xué)出版社，2021
主編《醫(yī)學(xué)教學(xué)導(dǎo)論》,，上海交通大學(xué)出版社,，2023
副主編《全球健康學(xué)》，人民衛(wèi)生出版社,，2023
主編《醫(yī)學(xué)微生物學(xué)》第2版,，人民衛(wèi)生出版社，2021
主編《病原生物學(xué),，第3版》,，科學(xué)出版社，2021
主編《醫(yī)學(xué)微生物學(xué)（英文改編版）,，第2版》,，科學(xué)出版社，2021
主編《基礎(chǔ)醫(yī)學(xué)實(shí)驗(yàn)示范教程》,，人民衛(wèi)生出版社,，2020
主編《Medical Microbiology》，人民衛(wèi)生出版社,，2020
主編《醫(yī)學(xué)微生物學(xué)》,，人民衛(wèi)生出版社，2019
總主編《病原生物學(xué)實(shí)驗(yàn)教程》,，人民衛(wèi)生出版社,，2019
副主編《噬菌體學(xué)：從理論到應(yīng)用》，科學(xué)出版社上海分社，2019
總主編《細(xì)胞與分子物學(xué)實(shí)驗(yàn)教程》,，人民衛(wèi)生出版社,，2018
總主編《醫(yī)學(xué)形態(tài)學(xué)實(shí)驗(yàn)教程》，人民衛(wèi)生出版社,，2018
總主編《醫(yī)學(xué)功能學(xué)實(shí)驗(yàn)教程》,，人民衛(wèi)生出版社，2018
總主編《醫(yī)用化學(xué)實(shí)驗(yàn)教程》,，人民衛(wèi)生出版社,，2018
副主編《醫(yī)學(xué)微生物學(xué) 第九版》，人民衛(wèi)生出版社,，2018
副主編《醫(yī)學(xué)微生物學(xué)學(xué)習(xí)指導(dǎo)與習(xí)題集》,，人民衛(wèi)生出版社，2018
主編《人體微生物組》,，人民衛(wèi)生出版社,，2017
主編《醫(yī)學(xué)整合課程的實(shí)踐與研究》，上海交通大學(xué)出版社,，2017
名譽(yù)主編《人體微生物組與健康》,，上海科學(xué)普及出版社,，2017
副主編《醫(yī)學(xué)微生物學(xué)》，全國(guó)高等教育醫(yī)學(xué)數(shù)字化規(guī)劃教材,，2014
主編《病原生物學(xué) 第2版》,，科學(xué)出版社，2013
主編《醫(yī)學(xué)微生物學(xué)》,，人民衛(wèi)生出版社 2013
主編《醫(yī)學(xué)微生物學(xué)實(shí)驗(yàn)技術(shù)》,，人民衛(wèi)生出版社。2010
主審《病原生物學(xué)實(shí)驗(yàn)》,，上海交通大學(xué)醫(yī)學(xué)院,，2009
主編《感染與優(yōu)生優(yōu)育》，第二軍醫(yī)大學(xué)出版社,，2009
主編《醫(yī)學(xué)微生物學(xué)教育教學(xué)》,，第二軍醫(yī)大學(xué)出版社，2008
主編《病原生物學(xué)綱要》,，科學(xué)出版社,，2008
主編《病原生物學(xué) 第1版》，科學(xué)出版社,，2007
主編《細(xì)胞微生物學(xué)》,，第二軍醫(yī)大學(xué)出版社，2004
主編《感染與優(yōu)生優(yōu)育》，黑龍江科技出版社,，1996
主編《克隆識(shí)別》,，北京協(xié)和大學(xué)出版社，1994
專利
鉤端螺旋體兩個(gè)疫苗候選的外膜蛋白 ZL 2007 1 0042222.X
榮譽(yù)及獎(jiǎng)項(xiàng)
醫(yī)理協(xié)同,，探索基礎(chǔ)醫(yī)學(xué)拔尖創(chuàng)新人才培養(yǎng)新模式獲2022年上海市教學(xué)成果一等獎(jiǎng)（排名第1）
能力導(dǎo)向的進(jìn)階式基礎(chǔ)醫(yī)學(xué)實(shí)驗(yàn)教學(xué)體系建構(gòu)與實(shí)踐獲2022年上海市教學(xué)成果二等獎(jiǎng)（排名第2）
突顯學(xué)生主體,，強(qiáng)化培養(yǎng)過(guò)程的基礎(chǔ)醫(yī)學(xué)研究生培養(yǎng)體系的創(chuàng)新與實(shí)踐獲2022年上海市教學(xué)成果二等獎(jiǎng)（排名第3）
基于MIFS理念的跨學(xué)科融合性拔尖人才培養(yǎng)體系的構(gòu)建與實(shí)踐獲上海市教學(xué)成果二等獎(jiǎng)（排名第3）
新時(shí)代復(fù)合型醫(yī)學(xué)人才培養(yǎng)的探索與實(shí)踐獲上海市教學(xué)成果特等獎(jiǎng)（排名第8）
《醫(yī)學(xué)微生物學(xué)（第9版）》獲全國(guó)優(yōu)秀教材一等獎(jiǎng)（副主編）
2021年度教育部“拔尖計(jì)劃2.0”優(yōu)秀教師獎(jiǎng)
突破·重構(gòu)·融合：基于“守正創(chuàng)新”的《醫(yī)學(xué)微生物學(xué)》混合式金課的建設(shè)與實(shí)踐獲上海交通大學(xué)2021年度教學(xué)成果特等獎(jiǎng)（排名第1）
基于MIFS理念的跨學(xué)科融合性拔尖人才培養(yǎng)體系的構(gòu)建與實(shí)踐獲上海交通大學(xué)2021年度教學(xué)成果一等獎(jiǎng)（排名第3）
知識(shí)重構(gòu) 能力優(yōu)先，教學(xué)改革牽引的基礎(chǔ)醫(yī)學(xué)教材體系建設(shè)獲上海交通大學(xué)2021年度教學(xué)成果二等獎(jiǎng)（排名第2）
建設(shè)榮譽(yù)課程體系,，培養(yǎng)學(xué)術(shù)型創(chuàng)新人才獲2020年上海交通大學(xué)教學(xué)成果二等獎(jiǎng)（排名第7）
生物醫(yī)學(xué)科學(xué)人才培養(yǎng)生態(tài)體系的構(gòu)建與實(shí)踐獲2020上海交通大學(xué)教學(xué)成果特等獎(jiǎng)（排名第1）
能力為核心,、融合為手段重構(gòu)基礎(chǔ)醫(yī)學(xué)課程獲2020年上海交通大學(xué)教學(xué)成果一等獎(jiǎng)（排名第15）
突出學(xué)生主體、強(qiáng)化培養(yǎng)過(guò)程的研究生培養(yǎng)體系創(chuàng)新與實(shí)踐獲2020年上海交通大學(xué)教學(xué)成果特等獎(jiǎng)（排名第3）
基于優(yōu)質(zhì)多元信息化平臺(tái),，構(gòu)筑“智能+”醫(yī)學(xué)金課堂獲2020年第九屆廣東省教育教學(xué)成果二等獎(jiǎng) （排名第4）
基礎(chǔ)醫(yī)學(xué)整合課程改革團(tuán)隊(duì)獲2019年上海交通大學(xué)教書(shū)育人獎(jiǎng)一等獎(jiǎng)（排名第1）
基于多元化 信息化優(yōu)質(zhì)平臺(tái),，構(gòu)筑“智能+”醫(yī)學(xué)金課堂獲2019年南方醫(yī)科大學(xué)教育教學(xué)成果獎(jiǎng)一等獎(jiǎng)
能力導(dǎo)向梯度實(shí)驗(yàn)教學(xué)體系建設(shè)與實(shí)踐獲2019年上海交通大學(xué)教學(xué)成果特等獎(jiǎng)（排名第1）
教育教學(xué)獲2019年上海市“為人、為學(xué),、為師”先進(jìn)宣傳典型
夯實(shí)醫(yī)教協(xié)同,，綜合性大學(xué)“有靈魂的卓越醫(yī)學(xué)創(chuàng)新人才培養(yǎng)體系”構(gòu)建與實(shí)踐獲2018年高等教育國(guó)家級(jí)教學(xué)成果一等獎(jiǎng)（排名第2）
深化醫(yī)教協(xié)同，校院聯(lián)動(dòng)構(gòu)建有靈魂的卓越醫(yī)學(xué)創(chuàng)新人才培養(yǎng)體系獲2018年上海市教學(xué)成果特等獎(jiǎng)（排名第2）
基礎(chǔ)醫(yī)學(xué)ASK 全人教育體系的實(shí)踐與推廣獲2017年上海交通大學(xué)教學(xué)成果特等獎(jiǎng)
深化醫(yī)教協(xié)同推進(jìn)卓越醫(yī)學(xué)人才培養(yǎng)獲2017年第五屆全國(guó)教育改革創(chuàng)新獎(jiǎng)
教育教學(xué)獲2017年上海交通大學(xué)教書(shū)育人一等獎(jiǎng)
致遠(yuǎn)學(xué)院項(xiàng)目主任團(tuán)隊(duì)獲2017年上海交通大學(xué)教書(shū)育人二等獎(jiǎng)
2017年上海交通大學(xué)十佳班主任上海交通大學(xué)
2017年上海交通大學(xué)醫(yī)學(xué)院十佳班導(dǎo)師
醫(yī)學(xué)生創(chuàng)新能力培養(yǎng)體系的建設(shè)與實(shí)踐獲2016年上海交通大學(xué)教學(xué)成果一等獎(jiǎng)
基于國(guó)際化與信息化的北美醫(yī)學(xué)課程和評(píng)估體系及師資隊(duì)伍建設(shè)的探索與實(shí)踐獲2016年上海交通大學(xué)教學(xué)成果一等獎(jiǎng)
基于器官系統(tǒng)的整合課程體系的改革與實(shí)踐獲2015年上海交通大學(xué)教學(xué)成果特等獎(jiǎng)（排名第1）
醫(yī)學(xué)法語(yǔ)教學(xué)中的多主體,、多模式國(guó)際合作的創(chuàng)新實(shí)踐獲2015年上海交通大學(xué)教學(xué)成果二等獎(jiǎng)（排名第1）
以學(xué)生創(chuàng)新能力培養(yǎng)為核心的基礎(chǔ)醫(yī)學(xué)實(shí)踐教學(xué)模式的構(gòu)建與應(yīng)用獲2014年上海市教學(xué)成果二等獎(jiǎng)（排名第1）
以學(xué)生創(chuàng)新能力培養(yǎng)為核心的基礎(chǔ)醫(yī)學(xué)實(shí)踐教學(xué)模式的構(gòu)建與應(yīng)用獲2014年上海交通大學(xué)教學(xué)成果一等獎(jiǎng)（排名第1）
2011年國(guó)家高等學(xué)校教學(xué)名師獎(jiǎng)
主編《病原生物學(xué)綱要》獲2011年上海交通大學(xué)第十三屆優(yōu)秀教材一等獎(jiǎng)
病原生物學(xué)教育教學(xué)體系的建立與完善獲2010年全國(guó)“十一五”教育科研成果特等獎(jiǎng)（排名第1）
2010年上海交通大學(xué)校長(zhǎng)獎(jiǎng)
融合式教學(xué)模式在病原生物學(xué)的發(fā)展與實(shí)踐獲2010年上海交通大學(xué)教學(xué)成果二等獎(jiǎng)（排名第1）
病原生物學(xué)教學(xué)團(tuán)隊(duì)獲2010年全國(guó)“十一五”教育科研先進(jìn)集體（負(fù)責(zé)人）
病原生物學(xué)教學(xué)團(tuán)隊(duì)獲2010年上海市優(yōu)秀教學(xué)團(tuán)隊(duì)（負(fù)責(zé)人）
2010年全國(guó)“十一五”教育科研先進(jìn)工作者
2009年全國(guó)優(yōu)秀教師
2009年上海市教學(xué)名師
病原生物學(xué)教學(xué)團(tuán)隊(duì)獲2009年上海市教育系統(tǒng)先進(jìn)集體（負(fù)責(zé)人）
病原生物學(xué)教學(xué)團(tuán)隊(duì)獲上海市文明班組（負(fù)責(zé)人）
病原生物學(xué)課程與教學(xué)模式的創(chuàng)新發(fā)展與實(shí)踐獲2009年上海市教學(xué)成果三等獎(jiǎng)
病原生物學(xué)教育教學(xué)體系的建立與完善獲2008年上海交通大學(xué)教學(xué)成果特等獎(jiǎng)
2007年獲寶鋼基金會(huì)優(yōu)秀教師獎(jiǎng)
2004年獲上海第二醫(yī)科大學(xué)校長(zhǎng)獎(jiǎng)
1996年獲霍英東教育基金會(huì)青年教師獎(jiǎng)
改革實(shí)驗(yàn)教學(xué),、加強(qiáng)學(xué)生能力培養(yǎng)獲1993年黑龍江省優(yōu)秀教學(xué)成果二等獎(jiǎng)
開(kāi)設(shè)課程
2020-今 《公共衛(wèi)生進(jìn)展概述》
2020-今 《公共衛(wèi)生研究前沿》
2020-今 國(guó)家級(jí)一流課程（國(guó)家級(jí)精品在線開(kāi)放課程）《醫(yī)學(xué)微生物學(xué)》
2019-今 在線開(kāi)放課程《醫(yī)學(xué)微生物學(xué)》
2019-今 上海市高校優(yōu)質(zhì)混合式示范課程《醫(yī)學(xué)微生物學(xué)》
2018-今 上海市精品課程《基礎(chǔ)醫(yī)學(xué)器官系統(tǒng)整合課程》（含《病原生物學(xué)》）
2017-今 聯(lián)盟規(guī)劃課程《醫(yī)學(xué)微生物學(xué)》，中國(guó)醫(yī)學(xué)教育慕課聯(lián)盟
Profile
Name：Xiao-Kui Guo
Gender：Male
Date of birth：1964.9
Degree：Ph.D.
Title： Professor
Email：[email protected]
Address：280 S. Chongqing Rd, Shanghai, China 200025
Office Tel：021-63846590*776712
Education
1982/09－1986/06 Sichuan University
1988/09－1991/06 Harbin Medical University
1997/09－2000/06 Aichi Gakuin University Japan
Appointments
1986/08－2000/06 Department of Medical Microbiology, Harbin Medical University
2000/07－2019/06 Basic Medical College, Shanghai Jiao Tong University School of Medicine
2019/07－present School of Global Health, Chinese Centre for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine
Academic Participation and Activities
Chinese Society for Microbiology, Council Member;
Committee of Medical Microbiology and Immunology, Vice-Chairman;
Medical Bacteriology Group, Chairman
Microecology branch, China Preventive Medicine Association, Vice- Chairman
Teaching Committee of Chinese Society for Microbiology, Vice- Chairman
Committee of Microecology and Health Education, China Medical Association, Vice- Chairman
Shanghai Society for Microbiology, Vice Director and Secretary General
Microbiome Professional Committee, Shanghai Society for Microbiology, Chairman
Research interest
One health science; Antibiotics-resistant bacteria control; zoonosis;
醫(yī)學(xué)院主頁(yè)
