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吳文郁

作者:   發(fā)布時(shí)間 :2024年01月05日


姓名:吳文郁  

職稱:助理研究員

職務(wù):行政管理辦公室科員

聯(lián)系方式:

辦公室地址:上海市黃浦區(qū)重慶南路280號(hào)老紅樓407

辦公室電話:021-63846590轉(zhuǎn)776428

郵箱:wen[email protected]

 

教育經(jīng)歷(從本科開始)

2011-2015年 中國(guó)農(nóng)業(yè)大學(xué) 動(dòng)物科學(xué)學(xué)士

2015-2018年 中國(guó)科學(xué)院大學(xué) 生物工程碩士

2018-2023年 上海交通大學(xué) 生物學(xué)博士

 

工作經(jīng)歷

2023.10~至今,,上海交通大學(xué),全球健康學(xué)院,,助理研究員


社會(huì)/學(xué)術(shù)任職和活動(dòng)

2025~至今,,中國(guó)生物物理學(xué)會(huì),會(huì)員

2024~至今,,上海寄生蟲學(xué)會(huì),,會(huì)員

2023~至今,上海市生物物理學(xué)會(huì),,會(huì)員

 

科研方向/主要研究?jī)?nèi)容

急性髓系白血病的基礎(chǔ)和臨床轉(zhuǎn)化研究,。全健康科學(xué)/人獸共患病。


科研項(xiàng)目

項(xiàng)目編號(hào)

項(xiàng)目類型

項(xiàng)目名稱

起止年月

備注

2024QN083

上海市衛(wèi)健委

硫化砷靶向PML蛋白的分子機(jī)制及熒光探針早期診斷耐藥型白血病的研究

2024.05-2026.12

主持

BJ1-3000-24-0067

上海市教委

上海高校教師產(chǎn)學(xué)研踐習(xí)計(jì)劃

2024.09-2025.09

主持

WK2406

上海交通大學(xué)醫(yī)學(xué)院

全球“全健康”理念對(duì)公共衛(wèi)生事業(yè)發(fā)展的研究

2024.05-2025.05

主持

KJ3-0214-24-0014

上海交通大學(xué)

硫化砷靶向PML蛋白的分子機(jī)制的研究

2023.12-2026.12

主持

2025YFE0104200

科技部

One Health理念下地理環(huán)境對(duì)中塔人畜共患病影響及預(yù)測(cè)預(yù)警

2025.03-2027.02

主要參與

32470957

國(guó)家自然科學(xué)基金

PRL2調(diào)控肥大細(xì)胞活化在銀屑病發(fā)生發(fā)展中的作用機(jī)制

2025.01-2028.12

主要參與

24142201300

上海市科學(xué)技術(shù)委員會(huì)

多技術(shù)平臺(tái)在冠狀病毒檢測(cè)及監(jiān)測(cè)中的應(yīng)用研究,

2024.12--2026.11

主要參與

20JC1410600

上海市科學(xué)技術(shù)委員會(huì)

PML核體亞細(xì)胞器為核心的抗腫瘤新策略研究

2021.01-2023.12

主要參與


發(fā)表論文(格式:國(guó)標(biāo)GBT7714-2015

[1] Zhou C, Wang S, Wang C, Qiang N, Xiu L, Hu Q, Wu W, Zhang X, Han L, Feng X, Zhu Z, Shi L, Zhang P, Yin K. Integrated surveillance and early warning system of emerging infectious diseases in China at community level: current status, gaps and perspectives. Sci One Health. 2024 Dec 30;4:100102.

[2] Wu W, Tan Y, Yin H, Yin H, Jiang M, et al. Phase separation is required for PML nuclear body biogenesis and function[J].FASEB journal : official publication of the Federation of American Societies for Experimental Biology.2023,37(6):e22986.

[3] Chen Z, Wang Q, Zhang H, Ma X, Wu W, et al. Purification, crystallization, and X-ray diffraction analysis of myocyte enhancer factor 2D and DNA complex[J].Protein expression and purification.2021,179:105788.

[4] Li Y, Ma X, Wu W, Chen Z, Meng G. PML Nuclear Body Biogenesis, Carcinogenesis, and Targeted Therapy[J].Trends in cancer.2020,6(10):889-906.

[5] Li Y, Ma X, Chen Z, Wu H, Wang P, Wu W, et al.B1 oligomerization regulates PML nuclear body biogenesis and leukemogenesis[J].Nature communications.2019,10(1):3789

[6] Wu W, Zhen X, Shi N. DNA-binding domain of myelin-gene regulatory factor: purification, crystallization and X-ray analysis[J].Acta crystallographica Section F, Structural biology communications.2017,73(Pt 7):393-7.

 


英文:

NameWenyuWu

DegreePhD                  

Title:  

Email Address: [email protected]

Office Address: Room 407, Building 1, 280 South Chongqing Road, Shanghai

Office Tel: 021-63846590*776428


Education2011. 09-2015. 07,,Chinese Agriculture University, Bachelor, Animal Science

2015. 09-2018. 07,,University of Chinese Academy of Sciences, Master, Biological Engineering

2018. 09-2023. 07  Shanghai Jiao Tong University School, Ph.D, Biology


Appointments

Academic Participation and Activities

[1] Zhou C, Wang S, Wang C, Qiang N, Xiu L, Hu Q, Wu W, Zhang X, Han L, Feng X, Zhu Z, Shi L, Zhang P, Yin K. Integrated surveillance and early warning system of emerging infectious diseases in China at community level: current status, gaps and perspectives. Sci One Health. 2024 Dec 30;4:100102.

[2] Wu W, Tan Y, Yin H, Yin H, Jiang M, et al. Phase separation is required for PML nuclear body biogenesis and function[J].FASEB journal : official publication of the Federation of American Societies for Experimental Biology.2023,37(6):e22986.

[3] Chen Z, Wang Q, Zhang H, Ma X, Wu W, et al. Purification, crystallization, and X-ray diffraction analysis of myocyte enhancer factor 2D and DNA complex[J].Protein expression and purification.2021,179:105788.

[4] Li Y, Ma X, Wu W, Chen Z, Meng G. PML Nuclear Body Biogenesis, Carcinogenesis, and Targeted Therapy[J].Trends in cancer.2020,6(10):889-906.

[5] Li Y, Ma X, Chen Z, Wu H, Wang P, Wu W, et al.B1 oligomerization regulates PML nuclear body biogenesis and leukemogenesis[J].Nature communications.2019,10(1):3789

[6] Wu W, Zhen X, Shi N. DNA-binding domain of myelin-gene regulatory factor: purification, crystallization and X-ray analysis[J].Acta crystallographica Section F, Structural biology communications.2017,73(Pt 7):393-7.


Research Interest

Dr. Wenyu Wu’s research focuses on the study of PML NBs and the pathogenesis of acute myeloid leukemia. Whole Health Sciences/Zoonoses.

 


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