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居家不懈怠,科研不停產(chǎn)——全球健康學院疫情期間科研工作取得新進展

作者:張彥,、韓樂飛   發(fā)布時間 :2022年05月27日

2022年春季持續(xù)的新冠疫情,,改變了醫(yī)學院原有的教學科研模式,。在醫(yī)學院疫情防控統(tǒng)一安排下,,全球健康學院教職工開啟了居家辦公模式,,盡力克服疫情的不利影響,,確保學院教學,、科研,、學院工作有序穩(wěn)步進行。

全球健康學院自成立以來,,不斷探索以全健康理念為核心的相關研究,。全健康理念是國際社會當前大力倡導的應對全球公共衛(wèi)生問題的新型思維范式。該理念以“人-動物-環(huán)境”交界面的整體思維為指導,,旨在通過多機構,、跨學科、跨地域的協(xié)同合作,,可持續(xù)性地促進人類,、動物和環(huán)境的共同健康與和諧發(fā)展。

20221-5月,,全球健康學院在全健康領域的科研工作不斷取得新進展,、新突破。上月,,由全球健康學院周曉農(nóng)研究員,、郭曉奎教授研究團隊領銜撰寫的通信文章在國際頂尖學術期刊《自然(Nature)》雜志發(fā)表。文章介紹了全球全健康指數(shù)(global One Health index, GOHI)的構建過程并高度概括了GOHI的創(chuàng)新價值和應用前景,。



同時,,研究團隊建立GOHI指標體系和數(shù)據(jù)庫,,探索出一套對指標數(shù)據(jù)進行標化、賦分和綜合測算的技術路徑,,開展了對全球146個國家/地區(qū)GOHI得分的分析研究,。GOHI指標旨在從整體視角構建的全健康評估框架,并以此衡量各個國家/地區(qū)全健康最佳實踐間的差距,,為制定適應特定社會生態(tài)環(huán)境的全健康戰(zhàn)略目標和實施路徑提供參考,。相關研究成果已經(jīng)發(fā)表在國際高水平學術研究期刊Infectious Diseases of Poverty

20221-5月,,以全球健康學院署名發(fā)表的論文共28篇,,其中以學院為第一單位發(fā)表論文共10篇。此外,,學院組織師生編寫的專著《全健康科技進展2021》即將出版,。


附已發(fā)表(接收)論文列表:

[1] Zhang XX, Liu JS, Han LF, Simm G, Guo XK, Zhou XN*: One Health: new evaluation framework launched. Nature 2022, 604:625.

[2] Zhang XX#, Liu JS#, Han LF, Xia S, Li S-Z, Li OY, Kassegne KK, Li M, Yin K, Hu QQ, Xiu LS, Zhu YY, Huang LY, Wang XC, Zhang Y, Zhao HQ, Yin JX, Jiang TG, Li Q, Fei SW, Gu SY, Chen FM, Zhou N, Cheng ZL, Xie Y, Li HM, Chen J, Guo ZY,  Feng JX, Ai L, Xue JB, Ye Q, Grant L, Song JX, Simm G, Utzinger J, Guo XK*, Zhou XN*: Towards a global One Health index: a potential assessment tool for One Health performance. Infectious Diseases of Poverty 2022, 11:57.

[3] Fu X, Lyu L, Wang Y, Zhang Y, Guo X, Chen Q, Liu C*: Safety assessment and probiotic characteristics of Enterococcus lactis JDM1. Microb Pathog 2022, 163:105380.

[4] Hong Z, Li L, Zhang L, Wang Q, Xu J, Li S, Zhou XN*: Elimination of Schistosomiasis Japonica in China: From the One Health Perspective. China CDC Wkly 2022, 4:130-4.

[5] Jiang Y, Yuan Z, Liu H, Yin J, Qin Y, Jiang X, Xu J, Cao J, Shen Y*: Intestinal Protozoan Infections in Patients with Diarrhea - Shanghai Municipality, Zhenjiang City, and Danyang City, China, 2011-2015 and 2019-2021. China CDC Wkly 2022, 4:143-7.

[6] Li Y, Zhang L, Xiu L, Wang D, Zeng Y, Wang F, Yin Y, Peng J*: A Multiplex Molecular Assay for Detection of Six penA Codons To Predict Decreased Susceptibility to Cephalosporins in Neisseria gonorrhoeae. Antimicrob Agents Chemother 2022, 66:e0170921.

[7] Liang L, Shen Y, Hu Y, Liu H, Cao J*: cGAS exacerbates Schistosoma japonicum infection in a STING-type I IFN-dependent and independent manner. PLoS Pathog 2022, 18:e1010233.

[8] Lin P, Sun J, Lou X, Li D, Shi Y, Li Z, Ma P, Li P, Chen S, Jin W, Liu S, Chen Q, Gao Q, Zhu L, Xu J, Zhu M, Wang M, Liang K, Zhao L, Xu H, Dong K, Li Q, Cheng X*, Chen J*, Guo X*: Consensus on potential biomarkers developed for use in clinical tests for schizophrenia. Gen Psychiatr 2022, 35:e100685.

[9] Lv C, Deng W, Wang L, Qin Z, Zhou X*, Xu J*: Molecular Techniques as Alternatives of Diagnostic Tools in China as Schistosomiasis Moving towards Elimination. Pathogens 2022, 11.

[10] Qian MB, Utzinger J, Li SZ, Montresor A, Zhou XN*: Towards elimination of soil-transmitted helminthiasis in China. Lancet Reg Health West Pac 2022, 22:100455.

[11] Sun L#, Xiu L#, Zhang C#, Xiao Y, Li Y, Zhang L, Ren L*, Peng J*: Detection and classification of SARS-CoV-2 using high-resolution melting analysis. Microb Biotechnol 2022.

[12] Wang DQ, Liang XH, Lu SN, Ding W, Huang J, Wen X, Lv S, Xiao N, Husain L, Zhou XN*: China's long march to malaria elimination: a case of adaptive management. Malar J 2022, 21:38.

[13] Wang H#, Yan D#, Li Y#, Gong Y#, Mai Y#, Li B, Zhu X, Wan X, Xie L, Jiang H, Zhang M, Sun M*, Yao Y*, Zhu Y*: Clinical and antibody characteristics reveal diverse signatures of severe and non-severe SARS-CoV-2 patients. Infect Dis Poverty 2022, 11:15.

[14] Wang Y#, Gong W#, Zhou H, Hu Y, Wang L, Shen Y, Yu G*, Cao J*: A Novel miRNA From Egg-Derived Exosomes of Schistosoma japonicum Promotes Liver Fibrosis in Murine Schistosomiasis. Front Immunol 2022, 13:860807.

[15] Zhang J#, Qiu J#, Zhou W, Cao J, Hu X, Mi W, Su B, He B*, Qiu J*, Shen L*: Neuropilin-1 mediates lung tissue-specific control of ILC2 function in type 2 immunity. Nat Immunol 2022, 23:237-50.

[16] Zhao S, Wang K, Chong MKC, Musa SS, He M, Han L*, He D*, Wang MH: The non-pharmaceutical interventions may affect the advantage in transmission of mutated variants during epidemics: A conceptual model for COVID-19. J Theor Biol 2022, 542:111105.

[17] Zhou XN*: Infectious Diseases of Poverty: progress achieved during the decade gone and perspectives for the future. Infect Dis Poverty 2022, 11:1.

[18] Cai M, Pu B, Wang Y, Lv L, Jiang C, Fu X, Zhang Y, Zhao W, Dong K, Yang Y, Liu Y, Wei Y, Zhang Z, Li J, Guo X, Liu C*, Qin J*: A Plasmid With Conserved Phage Genes Helps Klebsiella pneumoniae Defend Against the Invasion of Transferable DNA Elements at the Cost of Reduced Virulence. Front Microbiol 2022, 13:827545.

[19] Chang C, Yu X, Guo W, Guo C, Guo X*, Li Q*, Zhu Y*: Bacteriophage-Mediated Control of Biofilm: A Promising New Dawn for the Future. Front Microbiol 2022, 13:825828.

[20] Jin LL, Deng L, Bartlett M, Ren YP, Lu JH, Chen Q, Pan YX, Wang H, Guo XK and Liu C: A Novel Herbal Extract Blend Product Prevents Particulate Matters-Induced Inflammation by Improving Gut Microbiota and Maintaining the Integrity of the Intestinal Barrier. Nutrients, 2022 (Accepted)

[21] 吳哲元,王心怡,,郭曉奎,,周曉農(nóng),夏尚,。大數(shù)據(jù)驅(qū)動的全健康決策支持文獻研究,。中國衛(wèi)生信息管理雜志,2022,,19(2):286-292,。

[22] 劉婧姝,張曉溪,,郭曉奎,。全健康的起源、內(nèi)涵及展望,。中國寄生蟲學與寄生蟲病雜志,,202211-11,。

[23] 費思偉,,許靖姍,周曉農(nóng),。全健康:人獸共患病防控的新思考,。中國血吸蟲病防治雜志,2022,,11-6,。

[24] 周曉農(nóng)。以全健康理念推進人獸共患病預防與控制。中國寄生蟲學與寄生蟲病雜志,,2022,,112-19

[25] 王向澄,,苗力元,。芝加哥健康治理數(shù)字化轉(zhuǎn)型研究:以健康云圖的發(fā)展于應用為例,全球城市研究,,2022。(已接收)

[26] 王向澄,,苗力元,。健康治理數(shù)字化轉(zhuǎn)型的發(fā)展與應用,全球城市發(fā)展報告,,2022,。(已接收)

[27] 王向澄,張曉旺,。醫(yī)聯(lián)體協(xié)作模式的建立及功能性研究,,中國醫(yī)院,2022,。(已接收)

[28] 王向澄,。醫(yī)學社會學視角下的女性主義心理學研究,專著,,2022,。








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