姓名：殷堃 研究員/碩士生導(dǎo)師 (兼職博士生導(dǎo)師)
聯(lián)系方式：
辦公室地址：老紅樓410辦公室
辦公室電話：021-63846590*776972
郵箱：[email protected]
教育經(jīng)歷（從本科開(kāi)始）
2007年9月至2011年7月，中國(guó)農(nóng)業(yè)大學(xué) 水產(chǎn)養(yǎng)殖學(xué)學(xué)士
2011年3月至2016年7月，中國(guó)科學(xué)院大學(xué) 環(huán)境工程博士
工作經(jīng)歷
2021年2月至今 上海交通大學(xué)醫(yī)學(xué)院,，全球健康學(xué)院 研究員
2018年10月至2021年1月 美國(guó)康涅狄格大學(xué),，生物醫(yī)學(xué)工程系 博士后
2017年10月至2018年9月 美國(guó)賓夕法尼亞大學(xué)，機(jī)械工程與應(yīng)用力學(xué)系 博士后
2017年1月至2017年9月 美國(guó)俄亥俄州立大學(xué),，生物醫(yī)學(xué)工程系 博士后
社會(huì)/學(xué)術(shù)任職和活動(dòng)
中華預(yù)防醫(yī)學(xué)會(huì)全球衛(wèi)生分會(huì)委員,、中國(guó)醫(yī)學(xué)裝備協(xié)會(huì)應(yīng)急救治裝備分會(huì)常委、上海市食品協(xié)會(huì)食品安全分會(huì)委員,；Science in One Health 副編審,；Zoonoses 青年編委；Frontiers in Public Health,、Frontiers in Medicine,、Biosensors、Sensors客座編輯,；ACS Nano,、Theranostics、Biosensors and Bioelectronic,、ACS Sensors,、Sensors and Actuators B: Chemical 等中科院一區(qū)期刊審稿人。
科研方向/主要研究?jī)?nèi)容
1）光學(xué)生物傳感,；
2）微流控器件與便攜式檢測(cè)平臺(tái),；
3）即時(shí)診斷；
4）環(huán)境健康與耐藥防控,。
科研項(xiàng)目
項(xiàng)目編號(hào) |
項(xiàng)目類型 |
項(xiàng)目名稱 |
起止年月 |
備注 |
22104090 |
國(guó)家自然科學(xué)基金 |
基于CRISPR/Cas識(shí)別機(jī)理的新型冠狀病毒多靶位可視化診斷方法研究 |
202201-202412 |
項(xiàng)目負(fù)責(zé)人 |
22ZR1436200 |
上海市自然科學(xué)基金 |
基于全健康的新發(fā)突發(fā)傳染病移動(dòng)互聯(lián)快速診斷與監(jiān)測(cè)預(yù)警平臺(tái) |
202204-202503 |
項(xiàng)目負(fù)責(zé)人 |
ZDYF2022SHFZ321 |
海南省自然科學(xué)基金 |
全健康視角下微塑料污染環(huán)境風(fēng)險(xiǎn)預(yù)警及對(duì)人體危害評(píng)估技術(shù)的研究 |
202209-202509 |
課題負(fù)責(zé)人 |
發(fā)表論文（格式：國(guó)標(biāo)GB／T7714-2015）
1. Huimin Li, Yi Xie, Fumin Chen, Huiwen Bai, Leshan Xiu, Xiaonong Zhou, Xiaokui Guo, Qinqin Hu and Kun Yin*. Amplification-free CRISPR/Cas detection technology: challenges, strategies, and perspectives. Chemical Society Reviews, 2023. (IF=60.615)
2. Yi Xie, Huimin Li, Fumin Chen, Srisruthi Udayakumar, Khyati Arora, Hui Chen, Yang Lan, Qinqin Hu, Xiaonong Zhou, Xiaokui Guo, Leshan Xiu and Kun Yin*. Clustered Regularly Interspaced short palindromic repeats‐Based Microfluidic System in Infectious Diseases Diagnosis: Current Status, Challenges, and Perspectives. Advanced Science, 2022 (IF=17.521)
3. Kun Yin, Qiaoning Wang, Min Lv, Lingxin Chen*. Microorganism remediation strategies towards heavy metals. Chemical Engineering Journal, 2019, 360: 1553-1563. (IF= 16.744)
4. Kun Yin, Min Lv, Qiaoning Wang; Yixuan Wu; Chunyang Liao*, Lingxin Chen. Simultaneous Bioremediation and Biodetection of Mercury Ion through Surface Display of Carboxylesterase E2 from Pseudomonas Aeruginosa PA1. Water Research, 2016. 103: 383-390. (IF= 13.400)
5. Kun Yin, Fabiao Yu*, Weiwei Zhang, and Lingxin Chen*. A near-infrared ratiometric fluorescent probe for cysteine detection over glutathione indicating mitochondrial oxidative stress in vivo. Biosensors and Bioelectronics, 2015, 74: 156-164. (IF=12.545)
6. Kun Yin, Bowei Li, Xiaochun Wang, Weiwei Zhang* and Lingxin Chen*. Ultrasensitive colorimetric detection of Cu2+ ion based on catalyticoxidation of L-cysteine. Biosensors and Bioelectronics, 2015, 64: 81-87. (IF=12.545)
7. Kun Yin, Weiwei Zhang and Lingxin Chen*. Pyoverdine secreted by Pseudomonas aeruginosa as a biological recognition element for the fluorescent detection of furazolidone. Biosensors and Bioelectronics, 2014, 51: 90-96. (IF=12.545)
8. Kun Yin, Vikram Pandian, Karteek Kadimisetty, Carlos Ruiz, Kumarasen Cooper, Jianxin You, and Changchun Liu*. Synergistically enhanced colorimetric molecular detection using smart cup: a case for instrument-free HPV-associated cancer screening. Theranostics, 2019, 9: 2637-2645. (IF= 11.600)
9. Kun Yin, Xiong Ding, Zhiheng Xu, Ziyue Li, Xingyu Wang, Hui Zhao, Clifford Otis, Baikun Li, Changchun Liu*. Multiplexed colorimetric detection of SARS-CoV-2 and other pathogens in wastewater on a 3D printed integrated microfluidic chip. Sensors and Actuators B: Chemical, 2021, 130242. (IF=9.221)
10. Kun Yin, Yixuan Wu, Shasha Wang and Lingxin Chen*. A sensitive fluorescent biosensor for the detection of copper ion inspired by biological recognition element pyoverdine. Sensors and Actuators B: Chemical, 2016, 232: 257-263. (IF=9.221)
11. Kun Yin, Fabiao Yu, Dongyan Liu, Zhihong Xie and Lingxin Chen*. Cyanine-based colorimetric and fluorescent probe for the selective detection of diethylstilbestrol in seawater, shrimp and fish samples. Sensors and Actuators B: Chemical, 2016, 223: 799-805. (IF=9.221)
12. Kun Yin, Xiong Ding, Ziyue Li, Hui Zhao, Kumarasen Cooper, Changchun Liu*. Dynamic aqueous multiphase reaction system for one-pot CRISPR-Cas12a based ultrasensitive and quantitative molecular diagnosis. Analytical Chemistry, 2020, 92:8561-8568. (IF= IF=8.008)
13. Kun Yin, Xiong Ding, Ziyue Li, Maroun M. Sfeir, Enrique Ballesteros, Changchun Liu*. Autonomous lab-on-paper for multiplexed, CRISPR-based diagnostics of SARS-CoV-2. Lab on a Chip, 2021, (IF=7.517)
小組成員
胡沁沁,、修樂(lè)山
英文：
Name：Kun YIN
Degree：Ph.D
Title: Professor
Email Address: [email protected]
Office Address: Laohong Building 410
Office Tel: 021-63846590*776972
Education：
2007. 09-2011. 07，Chinese Agriculture University, Bachelor, Aquaculture
2011. 03-2016. 07,，University of Chinese Academy of Sciences, Ph.D, Environmental Engineering
Appointments：
2021. 02- Now Shanghai Jiao Tong University Medical School,，Professor
2018. 10-2021. 01 University of Connecticut，Postdoctoral Researcher
2017. 10-2018. 09 University of Pennsylvania,，Postdoctoral Researcher
2017. 01-2017. 09 The Ohio State University,，Postdoctoral Researcher
Academic Participation and Activities：
1. Huimin Li, Yi Xie, Fumin Chen, Huiwen Bai, Leshan Xiu, Xiaonong Zhou, Xiaokui Guo, Qinqin Hu and Kun Yin*. Amplification-free CRISPR/Cas detection technology: challenges, strategies, and perspectives. Chemical Society Reviews, 2023. (IF=60.615)
2. Yi Xie, Huimin Li, Fumin Chen, Srisruthi Udayakumar, Khyati Arora, Hui Chen, Yang Lan, Qinqin Hu, Xiaonong Zhou, Xiaokui Guo, Leshan Xiu and Kun Yin*. Clustered Regularly Interspaced short palindromic repeats‐Based Microfluidic System in Infectious Diseases Diagnosis: Current Status, Challenges, and Perspectives. Advanced Science, 2022 (IF=17.521)
3. Kun Yin, Qiaoning Wang, Min Lv, Lingxin Chen*. Microorganism remediation strategies towards heavy metals. Chemical Engineering Journal, 2019, 360: 1553-1563. (IF= 16.744)
4. Kun Yin, Min Lv, Qiaoning Wang; Yixuan Wu; Chunyang Liao*, Lingxin Chen. Simultaneous Bioremediation and Biodetection of Mercury Ion through Surface Display of Carboxylesterase E2 from Pseudomonas Aeruginosa PA1. Water Research, 2016. 103: 383-390. (IF= 13.400)
5. Kun Yin, Fabiao Yu*, Weiwei Zhang, and Lingxin Chen*. A near-infrared ratiometric fluorescent probe for cysteine detection over glutathione indicating mitochondrial oxidative stress in vivo. Biosensors and Bioelectronics, 2015, 74: 156-164. (IF=12.545)
6. Kun Yin, Bowei Li, Xiaochun Wang, Weiwei Zhang* and Lingxin Chen*. Ultrasensitive colorimetric detection of Cu2+ ion based on catalyticoxidation of L-cysteine. Biosensors and Bioelectronics, 2015, 64: 81-87. (IF=12.545)
7. Kun Yin, Weiwei Zhang and Lingxin Chen*. Pyoverdine secreted by Pseudomonas aeruginosa as a biological recognition element for the fluorescent detection of furazolidone. Biosensors and Bioelectronics, 2014, 51: 90-96. (IF=12.545)
8. Kun Yin, Vikram Pandian, Karteek Kadimisetty, Carlos Ruiz, Kumarasen Cooper, Jianxin You, and Changchun Liu*. Synergistically enhanced colorimetric molecular detection using smart cup: a case for instrument-free HPV-associated cancer screening. Theranostics, 2019, 9: 2637-2645. (IF= 11.600)
9. Kun Yin, Xiong Ding, Zhiheng Xu, Ziyue Li, Xingyu Wang, Hui Zhao, Clifford Otis, Baikun Li, Changchun Liu*. Multiplexed colorimetric detection of SARS-CoV-2 and other pathogens in wastewater on a 3D printed integrated microfluidic chip. Sensors and Actuators B: Chemical, 2021, 130242. (IF=9.221)
10. Kun Yin, Yixuan Wu, Shasha Wang and Lingxin Chen*. A sensitive fluorescent biosensor for the detection of copper ion inspired by biological recognition element pyoverdine. Sensors and Actuators B: Chemical, 2016, 232: 257-263. (IF=9.221)
11. Kun Yin, Fabiao Yu, Dongyan Liu, Zhihong Xie and Lingxin Chen*. Cyanine-based colorimetric and fluorescent probe for the selective detection of diethylstilbestrol in seawater, shrimp and fish samples. Sensors and Actuators B: Chemical, 2016, 223: 799-805. (IF=9.221)
12. Kun Yin, Xiong Ding, Ziyue Li, Hui Zhao, Kumarasen Cooper, Changchun Liu*. Dynamic aqueous multiphase reaction system for one-pot CRISPR-Cas12a based ultrasensitive and quantitative molecular diagnosis. Analytical Chemistry, 2020, 92:8561-8568. (IF= IF=8.008)
13. Kun Yin, Xiong Ding, Ziyue Li, Maroun M. Sfeir, Enrique Ballesteros, Changchun Liu*. Autonomous lab-on-paper for multiplexed, CRISPR-based diagnostics of SARS-CoV-2. Lab on a Chip, 2021, (IF=7.517)
14. Kun Yin, Vikram Pandian, Karteek Kadimisetty, Xin Zhang, Carlos Ruiz, Kumarasen Cooper, Changchun Liu*. Real-time colorimetric Quantitative Molecular Detection of infectious Diseases on Smartphone-based Diagnostic platform. Scientific Reports, 2020, 10：1-9. (IF= 4.996)
15. Chen Chen, Qinqin Hu and Kun Yin*. Visible transparency tuning and corresponding sensing application of opal photonic crystals. Optics Express. 2022, (IF= 3.833)
16. Kun Yin, Leming Sun, Zhen Fan, Huacan Lin, Yujian Huang, Scott Galster, Jeff, Kuret, Douglas Scharre, Mingjun Zhang*. Fluorescent peptide nanoparticles to monitor Aβ oligomers. IEEE-NANO, 2017 IEEE 17th International Conference on Nanotechnology, 2017, 25-28.
Research Interest：
Dr. Kun Yin’s research focuses on the development of optical biosensors, infectious disease diagnosis, and AMR monitoring, especially at the human-environment interface under the One Health concept: 1) Bridges gaps between different fields and opens new opportunities for the development of novel biosensors with high sensitivity and selectivity, which have outstanding advantages in practical applications. 2) Applies interdisciplinary approaches to develop new tools and methods to solve current life science challenges, such as disease diagnostics, medical therapeutics, and personalized medicine. 3) Explores wastewater surveillance of antimicrobial resistance at the human-animal-environment interface to improve our understanding of the spread of antimicrobial resistance.
醫(yī)學(xué)院主頁(yè)
