Name: Ariel Gilad
Title： Principal Investigator
Email: [email protected]
Tel: +97226758274
Research Interests
We are interested in studying how the brain encodes cognition at the brain-wide level. Sensory integration, perception, memory and learning are just several examples of the cognitive functions that we aim to understand. In the lab we take a mesoscale approach in which we aim to simultaneously image as many brain areas as possible as mice perform complex behavioral tasks. Complementing the mesoscale approach, we implement a microscale approach, using multi-area two-photon microscopy, optogenetics and labeling techniques to dissect the relevant neuronal sub-populations mediating different cognitive functions. Our goal is to obtain a cognitive brain-wide map where relevant information flows through specific processing streams based on demand.
Ten Selected Papers
*co-corresponding authors; #co-first authors
1. Gallero-Salas,Y., Laurenczy, B., Voigt, F., Gilad, A.*, and Helmchen, F.* Sensory and Behavioral Components of Neocortical Signal Flow in Discrimination Tasks with Short-term Memory. * - co-supervision. Neuron. 109, 1–14
2. Gilad, A., Maor, I., & Mizrahi, A. (2020). Learning-related population dynamics in the auditory thalamus. ELife, 9, 1–18.
3. Gilad, A., & Helmchen, F. (2020). Spatiotemporal refinement of signal flow through association cortex during learning. Nature Communications, 11(1), 1–14.
4. Gilad, A., Gallero-Salas, Y., Groos, D., and Helmchen, F., (2018). Behavioral strategy determines frontal or posterior location of short-term memory in neocortex. Neuron 99, 814–828.e7.
5. Helmchen, F., Gilad, A., and Chen, J.L. (2018). Neocortical dynamics during whisker-based sensory discrimination in head-restrained mice. Neuroscience 368, 57–69.
6. Gilad, A., Oz, R., and Slovin, H. (2017). Uncovering the Spatial Profile of Contour Integration from Fixational Saccades: Evidence for Widespread Processing in V1. Cerebral Cortex 27, 5261–5273.
7. Gilad, A., and Slovin, H. (2015). Population responses in V1 encode different figures by response amplitude. Journal of Neuroscience. 35, 6335–6349.
8. Gilad, A., Yair, P., Ayzenshtat, I., and Slovin, H. (2014). Figure-ground processing during fixational saccades in V1: indication for higher-order stability. Journal of Neuroscience. 34, 3247-3252.
9. Gilad, A., Meirovithz, E., and Slovin, H. (2013). Population responses to contour integration: early encoding of discrete elements and late perceptual grouping. Neuron. 78, 389-402.
10. Gilad, A., Meirovithz, E., Leshem, A., Arieli, A., and Slovin, H. (2012). Collinear stimuli induce local and cross-areal coherence in the visual cortex of behaving monkeys. PLoS. One. 7, e49391.
Collaborative Investigators
