研究論文： 1. Lu Q*, Liu J*, Zhao S*, Gomez Castro MF, Laurent-Rolle M, Dong J, Ran X, Damani-Yokota P, Tang H, Karakousi T, Son J, Kaczmarek ME, Zhang Z, Yeung ST, McCune BT, Chen RE, Tang F, Ren X, Chen X, Hsu JCC, Teplova M, Huang B, Deng H, Long Z, Mudianto T, Jin S, Lin P, Du J, Zang R, Su TT, Herrera A, Zhou M, Yan R, Cui J, Zhu J, Zhou Q, Wang T, Ma J, Koralov SB, Zhang Z, Aifantis I, Segal LN, Diamond MS, Khanna KM, Stapleford KA, Cresswell P, Liu Y, Ding S, Xie Q, Wang J. SARS-CoV-2 exacerbates proinflammatory responses in myeloid cells through C-type lectin receptors and Tweety family member 2. Immunity. 2021 Jun 8;54(6):1304-1319.e9. PMCID: PMC8106883. *Equal contribution. 2. Chen X*, Lu Q*, Zhou H, Liu J, Nadorp B, Lasry A, Sun Z, Lai B, Rona G, Zhang J, Cammer M, Wang K, Al-Santli W, Ciantra Z, Guo Q, You J, Sengupta D, Boukhris A, Zhang H, Liu C, Cresswell P, Dahia PLM, Pagano M, Aifantis I, Wang J. A membrane-associated MHC-I inhibitory axis for cancer immune evasion. Cell. 2023 Aug 31;186(18):3903-3920.e21. Epub 2023 Aug 8. PMID: 37557169. *Equal contribution. 3. Lu Q, Grotzke JE, Cresswell P. A novel probe to assess cytosolic entry of exogenous proteins. Nat Commun. 2018 Aug 6;9(1):3104. PMCID: PMC6079096. 4. Jiang Y*, Lu Q*, Wang Y*, Xu E, Ho A, Singh P, Wang Y, Jiang Z, Yang F, Tietjen GT, Cresswell P, Saltzman WM. Quantitating Endosomal Escape of a Library of Polymers for mRNA Delivery. Nano Lett. 2020 Feb 12;20(2):1117-1123. PMCID: PMC7195212. *Equal contribution. 5. Grotzke JE, Lu Q, Cresswell P. Deglycosylation-dependent fluorescent proteins provide unique tools for the study of ER-associated degradation. Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3393-8. PMCID: PMC3587246. 6. He K, Wan T, Wang D, Hu J, Zhou T, Tao W, Wei Z, Lu Q, Zhou R, Tian Z, Flavell RA, Zhu S. Gasdermin D licenses MHCII induction to maintain food tolerance in small intestine. Cell. 2023 Jul 6;186(14):3033-3048.e20. Epub 2023 Jun 15. PMID: 37327784. 7. Hu W, Zhang Y, Fei P, Zhang T, Yao D, Gao Y, Liu J, Chen H, Lu Q, Mudianto T, Zhang X, Xiao C, Ye Y, Sun Q, Zhang J, Xie Q, Wang PH, Wang J, Li Z, Lou J, Chen W. Mechanical activation of spike fosters SARS-CoV-2 viral infection. Cell Res. 2021 Aug 31; PMCID: PMC8406658. Impact factor: 46.3 8. Silberstein JL, Du J, Chan KW, Frank JA, Mathews II, Kim YB, You J, Lu Q, Liu J, Philips EA, Liu P, Rao E, Fernandez D, Rodriguez GE, Kong XP, Wang J, Cochran JR. Structural insights reveal interplay between LAG-3 homodimerization, ligand binding, and function. Proc Natl Acad Sci U S A. 2024 Mar 19;121(12):e2310866121. doi: 10.1073/pnas.2310866121. Epub 2024 Mar 14. PMID: 38483996; PMCID: PMC10962948. 綜述論文: 1. Wang J*, Lu Q*, Chen X*, Aifantis I. Targeting MHC-I inhibitory pathways for cancer immunotherapy. Trends Immunol. 2024 Mar;45(3):177-187. Epub 2024 Mar 2. PMID: 38433029. *Equal contribution. 2. Grotzke JE, Sengupta D, Lu Q, Cresswell P. The ongoing saga of the mechanism(s) of MHC class I-restricted cross-presentation. Curr Opin Immunol. 2017 Jun;46:89-96. PMCID: PMC5554740. 3. Sun J, Lu Q, Sanmamed MF, Wang J. Siglec-15 as an Emerging Target for Next-generation Cancer Immunotherapy. Clin Cancer Res. 2021 Feb 1;27(3):680-688. PubMed ID: 32958700. 4. Gu R, Mao T, Lu Q, Su T, Wang J. Myeloid dysregulation and therapeutic intervention in COVID-19. Semin Immunol. 2021. 2021 Nov 9:101524. PMID: 34823995. 專利: 1. Targeting SARS-CoV-2 viral-immune interaction for COVID-19 therapy (US20220089695A1) 2. Targeting MHC-I antigen presentation modulators for immunotherapy for cancer and autoimmune disorders (WO2024156006A2) |
