Xiao XH, Jin HZ, J Jin, Ma CM, T Yin, Zhou L, Lei H, Xu HZ, Liu W*, Wu YL* （通訊作者） 11(13)-dehydroivaxillin suppresses NF-?B activation in Non-Hodgkin's lymphoma cells by targeting IKKα/β. Cell Death Disease 2017 accepted Jing B, Liu M, Yang L, Cai HY, Chen JB, Li ZX, Kou X, Wu YZ, Qin DJ, Zhou L, Jin J, Lei H, Xu HZ, Wang WW, Wu YL*. （通訊作者） Naturally Occurring Pentacyclic Triterpenes as Inhibitors of Deubiquitinating Proteases USP7 Acta Pharmacologica Sinica 2017 accepted Wei W, Ma CM, Cao Y, Yang L, Huang Z, Qin DJ, Chen Y, Liu CX, Xia L, Lei H, Yu Y, Huang M, Tong Y, Xu HZ, Gao FH, Zhang J, Wu YL （通訊作者） Identification of H7 as a novel peroxiredoxin I inhibitor to induce differentiation of leukemia cells Oncotarget 2016 7(4):3873-3783 Masoumi K, Marfany G, Wu YL, Massoumi R. The activation of deubiquitination enzymes is controlled by SUMOylation in cancer. Future Oncology 2016 12(4):565-574 Wei W, Hao SG, Liu CX, Qin DJ, Song LL, Li Xia, Lei H, Yu Y, Wang WW, Pu JX, Sun HD, Xu HZ, Wu YL. （通訊作者） Targeting peroxiredoxin I potentiates 1,25-dihydroxyvitamin D3-induced cell differentiation in leukemia cells. Mol Med Rep. 2016 13(3):2201-2207 Xu Y, Liu JB, Wu YL, Guo QL, Sun HD, Chen GQ. Natural products against hematological malignancies and identification of their targets. Sci. China Life Sci 2015 58: 1–11 Hu JJ, Lei H, Fei XC, Liang S, Xu HZ, Qin DJ, Wang Y, Wu YL （通訊作者）, Li B NES1/KLK10 gene represses proliferation, enhances apoptosis and down-regulates glucose metabolism of PC3 prostate cancer cells. Scientific report 2015 5:17426 CaoY, Wei W, Zhang N, Yu Q , Xu WB, Chen GQ, Wu YL （通訊作者）, Yan H. Oridonin Stabilizes Retinoic Acid Receptor alpha through ROS-activated NF-kappa B signaling. BMC Cancer 2015 15(1):248 Dong-Jun Qin, Cai-Xia Tang, Li Yang, Hu Lei, Wei Wei, Ying-Ying Wang, Chun-Min Ma, Feng-Hou Gao, Han-Zhang Xu, Ying-Li Wu*. （通訊作者） Hsp90 is a novel target of CDDO-ME in inducing cell death of ovarian cancer cells. Plos One 2015 10(7):e0132337 Song LL, Tu YY, Xia L, Wang WW, Wei W, Ma CM, Wen DH, Lei H, Xu HZ, Wu YL. （通訊作者） Targeting Catalase but not Peroxiredoxins Enhances Arsenic Trioxide-induced Apoptosis in K562 Cells. Plos One 2014 9(8):e104985 Zhang Yue, Zhao FJ, Chen LL, Wang LQ, Nephew K, Wu YL （通訊作者）, Zhang S. MiR-373 Targeting of the Rab22a Oncogene Suppresses Tumor Invasion and Metastasis in Ovarian Cancer. Oncotarget 2014 5(23):12291-303 Wen D, Xu Z, Xia L, Liu X, Tu Y, Lei H, Wang W, Wang TD, Song L, Ma C, Xu H, Zhu W, Chen GQ, Wu YL*. （通訊作者） Important role of SUMOylation of spliceosome Factors in prostate cancer cells. J Proteome Res 2014 13(8):3571-82 Huang H, Cao Y, Wei W, Liu W, Lu SY, Chen YB, Wang Y, Yan H, Wu YL*. （通訊作者） Targeting Poly (ADP-ribose) polymerase Partially Contributes to Bufalin-induced Cell Death in Multiple Myeloma Cells. Plos One 2013 8(6):e66130 Yin QQ, Liu CX, Wu YL, Wu SF, Wang Y, Zhang X, Hu XJ, Pu JX, Lu Y, Zhou HC, Wang HL, Nie H, Sun HD, Chen GQ. Preventive and Therapeutic Effects of Adenanthin on Experimental Autoimmune Encephalomyelitis by Inhibiting NF-κB Signaling. J Immunol 2013 191(5):2115-25 Yang ZY, Jiang H, Qu Y, Wei Min, Min Yan, Zhu ZG, Liu BY, Chen GQ, Wu YL* （通訊作者）, Gu QL. Metallopanstimulin-1 Regulates Invasion and Migration of Gastric Cancer Cells Partially Through Integrin β4. Carcinogenesis 2013 34(12):2851-60 Wei W, Huang H, Zhao S, Liu W, Liu CX, Li C, Li JM, Wu YL* （通訊作者）, Yan H. Alantolactone induces apoptosis in chronic myelogenous leukemia sensitive or resistant to imatinib through NF-κB inhibition and Bcr/Abl protein deletion. Apoptosis 2013 18(9) ,1060-1070 He LC, Gao FH, Xu HZ, Zhao S, Ma CM, Li JE, Zhang S, Wu YL*. （通訊作者） Ikaros inhibits proliferation and, through upregualtion of Slug, increases metastatic ability of ovarian serous adenocarcinoma cells. Oncology reports 2012 28(4):1399-405 Gao FH #, Liu F #, Wei W, Liu LB, Xu MH, Guo ZY, Li W, Jiang B, Wu YL*. （通訊作者） Oridonin induces apoptosis and senescence by increasing hydrogen peroxide and glutathion depletion in colorectal cancer cells. Int J Mol Med 2012 29(4):649-655 Zhao S, Ma CM, Liu CX, Wei W, Liu B, Xu HZ, He LC, Yan Hua, Wu YL*. （通訊作者） Autophagy inhibition enhances isobavachalcone induced cell death in multiple myeloma cells. Int J Mol Med 2012 Jul 16:1-6 Liu B, Zheng Y, Wang TD, Xu HZ, Xia L, Wu YL, Chen GQ, Wang LS. Proteomic Identification of Common SCF Ubiquitin Ligase FBXO6-Interacting Glycoproteins in Three kinds of Cells. J Proteome Res 2012 11(3):1773-81 Liu CX, Yin QQ, Zhou HC, Wu YL （通訊作者）, Pu JX, Xia L, Liu W, Huang X, Jiang T, Wu MX, He LC, Zhao YX, Wang XL, Xiao WL, Chen HZ, Zha Q, Zhou AW, Wang LS, Sun HD, Chen GQ. Adenanthin targets peroxiredoxin I and II to induce differentiation of leukemic cells. Nature Chemical Biology 2012 8(5):486-93 He LC, Xu HZ, Gu ZM, Liu CX, Chen GQ, Wang YF, Wen DH, Wu YL. （通訊作者） Ikaros is degraded by proteasome-dependent mechanism in the early phase of apoptosis induction. Biochem Biophys Res Commun. 2011 406(3):430-4 Yang ZY,Qu Y, Zhang Q, Wei M, Liu CX, Chen XH, Yan M, Zhu ZG, Liu BY, Chen GQ, Wu YL* （通訊作者）, Gu QL*. Knockdown of Metallopanstimulin-1 Inhibits NF-κB Signaling at Different Levels: The Role of Apoptosis Induction of Gastric Cancer Cells. Int J Cancer 2011 130(12):2761-70 Qiao ZT, Wang WW, Wang L, Wen DH, Zhao YX, Wang Q, Meng QQ, Chen GQ, Wu YL* （通訊作者）, Zhou HC*. Design, Synthesis, and Biological Evaluation of Benzodiazepine-based SUMO-Specific Protease 1 Inhibitors. Bioorganic & Medicinal Chemistry Letters 2011 21(21):6389-92 Gu ZM, Liu CX, Wu SF, Zhao M, Xu HZ, Zhou HC, Chen GQ, Wu YL. （通訊作者） PU.1 directly regulates retinoic acid-induced expression of RIG-G in leukemia cells. FEBS Letters 2011 585(2):375-80 Gao F, Tang Q, Yang P, Fang Y, Li W, Wu YL. （通訊作者） Apoptosis inducing and differentiation enhancement effect of oridonin on the all-trans-retinoic acid-sensitive and -resistant acute promyelocytic leukemia cells. Int J Lab Hematol. Int J Lab Hematol 2010 32:114-22 Azouz A, Wu YL, Hillion J, Tarkanyi I, Karniguian A, Aradi J, Lanotte M, Chen GQ, Chehna M, Ségal-Bendirdjian E. Epigenetic plasticity of hTERT gene promoter determines retinoid capacity to repress telomerase in maturation-resistant acute promyelocytic leukemia cells. Leukemia 2010 24:613-22 Shen SM, Yu Y, Wu YL, Cheng JK, Wang LS, Chen GQ. Down-regulation of ANP32B, a novel substrate of caspase-3, enhances caspase-3 activation and apoptosis induction in myeloid leukemic cells. Carcinogenesis 2010 31:419-26 Gao FH, Wu YL （共同第一作者）, Zhao M, Liu CX, Wang LS, Chen GQ. Protein Kinase C-δ mediates down-regulation of heterogeneous nuclear ribonucleoprotein K protein: involvement in apoptosis induction. Exp Cell Res 2009 315:3250-3258 Zhang R, Wu YL, Zhao M, Liu C, Zhou L, Shen S, Liao S, Yang K, Li Q, Wan H. Role of HIF-1{alpha} in the regulation ACE and ACE2 expression in hypoxic human pulmonary artery smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 2009 297:631-40 Yan H, Wang YC, Li D, Wang Y, Liu W, Wu YL, Chen GQ. Arsenic Trioxide and Proteasome Inhibitor Bortezomib Synergistically Induce Apoptosis in Leukemia Cells: the Role of Protein Kinase C?. Leukemia 2007 21:1488-95 Wu YL, Dudognon C, Nguyen E, Hillion J, Pendino F, Tarkanyi I, Aradi J, Lanotte M, Tong JH, Chen GQ, Segal-Bendirdjian E. Immunodetection of human telomerase reverse-tranase (hTERT) re-appraised: nucleolin and telomerase cross paths. J Cell Sci 2006 119:2797-806 Liu W, Guo M, Xu YB, Li D, Zhou ZN, Wu YL, Chen Z, Kogan SC, Chen GQ. Induction of tumor arrest and differentiation with prolonged survival by intermittent hypoxia in a mouse model of acute myeloid leukemia. Blood 2006 107:698-707 Yan H, Peng ZG, Wu YL, Jiang Y, Yu Y, Huang Y, Zhu YS, Zhao Q, Chen GQ. Hypoxia-simulating agents and selective stimulation of arsenic trioxide-induced growth arrest and cell differentiation in acute promyelocytic leukemic cells. Haematologica 2005 90:1607-16 Yin T, Wu YL （共同第一作者）, Sun HP, Sun GL, Du YZ, Wang KK, Zhang J, Chen GQ, Chen SJ, Chen Z. Combined effects of As4S4 and imatinib on chronic myeloid leukemia cells and BCR-ABL oncoprotein. Blood 2004 104:4219-25. |
