Mykhaylo Demydchuka, Chris H. Hilla, Aiwu Zhou,GáborBunkóczia, Penelope E. Steinc, Denis Marchesanc, Janet E. Deanea and Randy J. Reada Insights into Hunter syndrome from the structure of iduronate-2-sulfatase Nat Commun. 2017 3:27943-27952 Hudie Wei,Haiyan Cai,Yuhao Ji,Pilin Wang,Qingqing Zhang, Yihui Lin,Weixiao Wang, Jinke Cheng, Naiyan Zeng, Ting Xu, Aiwu Zhou （通訊作者） Structural basis of a novel heterodimeric Fc for bispecific antibody production Oncotarget 2017 8:27943-27952 Zhang F, Wei H, Wang X, Bai Y, Wang P, Wu J, Jiang X, Wang Y, Cai H, Xu T,Zhou A. （通訊作者） Structural basis of a novel PD-L1 nanobody for immune checkpoint blockade. Cell Discov. 2017 3:27943-27952 Huang X, Zheng Y, Zhang F, Wei Z, Wang Y, Carrell RW, Read RJ, Chen GQ, Zhou A. （通訊作者） Molecular Mechanism of Z α1-antitrypsin Deficiency. J Biol Chem. 2016 22;291(30):15674-86 Wei H, Cai H, Wu J, Wei Z, Zhang F, Huang X, Ma L, Feng L, Zhang R, Wang Y, Ragg H, Zheng Y, Zhou A. （通訊作者） Heparin Binds Lamprey Angiotensinogen and Promotes Thrombin Inhibition through a Template Mechanism. J Biol Chem. 2016 291(48):24900-24911. Yang K, Wang M, Zhao Y, Sun X, Yang Y, Li X, Zhou A, Chu H, Zhou H, Xu J, Wu M, Yang J, Yi J. A redox mechanism underlying nucleolar stress sensing by nucleophosmin. Nat Commun. 2016 7:13599. Wang Y, Wang Y, Zhang H, Gao Y, Huang C, Zhou A, Zhou Y, Li Y. Sequential posttranslational modifications regulate PKC degradation. Mol Biol Cell. 2016 27(2):410-20. Huang X, Zhou J, Zhou A, Olson ST. Thermodynamic and kinetic characterization of the protein Z-dependent protease inhibitor (ZPI)-protein Z interaction reveals an unexpected role for ZPI Lys-239 J Biol Chem. 2015 290(15):9906-18 Wang Y, Wang Y, Zhang H, Gao Y, Huang C, Zhou A, Zhou Y, Li Y. Sequential Posttranslational Modifications Regulate PKC Degradation. Mol Biol Cell. 2015 mbc.E15-09-0624 Su Y, Al-Lamki RS, Blake-Palmer KG, Best A, Golder ZJ, Zhou A, Karet Frankl FE. Physical and functional links between anion exchanger-1 and sodium pump. J Am Soc Nephrol. 2015 26(2):400-9 Lin F, Zhou A, Wei Z. Crystallization and crystallographic studies of kallistatin. Acta Crystallogr F Struct Biol Commun. 2015 71(Pt 9):1135-8 Liu F, Zhou Q, Zhou J, Sun H, Wang Y, Zou X, Feng L, Hou Z, Zhou A, Zhou Y, Li Y. 14-3-3τ promotes surface expression of Cav2.2 (α1B) Ca2+ channels. J Biol Chem. 2015 290(5):2689-98 Qi X, Chan WL, Read RJ, Zhou A, Carrell RW. Temperature-responsive release of thyroxine and its environmental adaptation in Australians. Proc Biol Sci. 2014 281(1779):20132747 Chen J, Xu H, Zou X, Wang J, Zhu Y, Chen H, Shen B, Deng X, Zhou A, Chin YE,Rauscher FJ 3rd, Peng C, Hou Z. Snail recruits Ring1B to mediate tranional repression and cell migration in pancreatic cancer cells. Cancer Res. 2014 74(16):4353-63 Zhao Y, Zhang X, Chen Y, Lu S, Peng Y, Wang X, Guo C, Zhou A, Zhang J, Luo Y, Shen Q, Ding J, Meng L, Zhang J. Crystal Structures of PI3Kα Complexed with PI103 and Its Derivatives: New Directions for Inhibitors Design. ACS Med Chem Lett. 2014 5(2):138-42 Li J, Xu Y, Long XD, Wang W, Jiao HK, Mei Z, Yin QQ, Ma LN, Zhou A, Wang LS, Yao M, Xia Q, Chen GQ. Cbx4 governs HIF-1α to potentiate angiogenesis of hepatocellular carcinoma by its SUMO E3 ligase activity. CANCER CELL 2014 25(1):118-31 Chan WL, Zhou A, Read RJ. Towards engineering hormone-binding globulins as drug delivery agents. PLoS One 2014 9(11) Chan WL, Carrell RW, Zhou A, Read RJ How changes in affinity of corticosteroid-binding globulin modulate free cortisol concentration. J Clin Endocrinol Metab. 2013 98(8):3315-22 Huang X, Yan Y, Tu Y, Gatti J, *Broze GJ Jr, *Zhou A （通訊作者）,*Olson ST Structural basis for catalytic activation of protein Z-dependent protease inhibitor (ZPI) by protein Z. BLOOD 2012 23;120(8):1726-33 Liu CX, Yin QQ, Zhou HC, Wu YL, Pu JX, Xia L, Liu W, Huang X, Jiang T, Wu MX, He LC, Zhao YX, Wang XL, Xiao WL, Chen HZ, Zhao Q, Zhou A, Wang LS, Sun HD, Chen GQ. Adenanthin targets peroxiredoxin I and II to induce differentiation of leukemic cells. Nat Chem Biol. 2012 8;8(5): 486-93. Carrell R, Qi X, Zhou A. Serpins as hormone carriers: modulation of release. Methods Enzymol. 2011 501:89-103 Read RJ, Zhou A, Stein PE. Solving serpin crystal structures. Methods Enzymol. 2011 501:49-61 Su Y, Blake-Palmer KG, Fry AC, Best A, Brown AC, Hiemstra TF, Horita S, Zhou A, Toye AM, Karet FE. Glyceraldehyde 3-phosphate dehydrogenase is required for band 3 (anion exchanger 1) membrane residency in the mammalian kidney Am J Physiol Renal Physiol. 2011 300(1):F157-66 X Qi, F Loiseau, W Chan, Y Yan, Z Wei, L Milroy, R Myers, S V Ley, R J Read, R W Carrell, *Zhou A. （通訊作者） Allosteric modulation of hormone release from thyroxine and corticosteroid binding-globulins. J. Biol. Chem. 2011 18, 16163-16173. Cameron A, Henley D, Carrell R, Zhou A, Clarke A, Lightman S. Temperature-responsive release of cortisol from its binding globulin: a protein thermocouple J Clin Endocrinol Metab. 2010 95(10):4689-95. *Zhou A （通訊作者）,*Carrell R.W, Murphy M.P., Wei Z, Yan Y,Stanley P. L D, Stein P.E, Broughton P.F, Read R J. A redox switch in angiotensinogen modulates angiotensin release. NATURE 2010 468(7320):108-11 Wei Z, Yan Y, Carrell RW, *Zhou A. （通訊作者） Crystal structure of protein Z-dependent inhibitor complex shows how protein Z functions as a cofactor in the membrane inhibition of factor X. BLOOD 2009 22; 114(17): 3662-7. *Zhou A （通訊作者）, Wei Z, Read RJ, Carrell RW. Structural mechanism for the carriage and release of thyroxine in the blood. Proc Natl Acad Sci U S A. 2006 103(36): 13321-6 |
