| Wang Y, Ge YH, Wang YX, Liu T, Law PY, Loh HH,, Qiu Y. |
Modulation of mTOR Activity by μ-Opioid Receptor is Dependent upon the Association of Receptor and FK506-Binding Protein 12. |
CNS Neurosci Ther |
2015 |
21(7):591-8 |
| Jiang S, Yang W, Qiu Y,, Alzheimer's Disease Neuroimaging Initiative (ADNI) |
Identification of Novel Quantitative Traits-Associated Susceptibility Loci for APOE ε 4 Non-Carriers of Alzheimer's Disease |
Curr Alzheimer Res |
2015 |
12(3):218-27 |
| Wang Y, Wang YX, Liu T, Law PY, Loh HH, Qiu Y, |
μ-Opioid receptor attenuates Aβ oligomers-induced neurotoxicity through mTOR signaling. |
CNS Neurosci Ther |
2015 |
21(1):8-14 |
| Song Y, Lu HZ, Xu JR, Wang XL, Zhou W, Hou LN, Zhu L, Yu ZH,, Cui YY. |
Carbocysteine restores steroid sensitivity by targeting histone deacetylase 2 in a thiol/GSH-dependent manner |
Pharmacol Res |
2015 |
91:88-98 |
| Zhao Q, Gu X, Zhang C, Lu Q,, Xu L |
Blocking M2 muscarinic receptor signaling inhibits tumor growth and reverses epithelial-mesenchymal transition (EMT) in non-small cell lung cancer (NSCLC) |
Cancer Biol Ther |
2015 |
16(4):634-43 |
| Guan YY, Liu HJ, Luan X, Xu JR, Lu Q, Liu YR, Gao YG, Zhao M,, Fang C. |
Raddeanin A, a triterpenoid saponin isolated from Anemone raddeana, suppresses the angiogenesis and growth of human colorectal tumor by inhibiting VEGFR2 signaling |
Phytomedicine |
2015 |
22(1):103-10 |
| Yu DH, Liu YR, Luan X, Liu HJ, Gao YG, Wu H, Fang C, |
Nanoparticles with IF7-conjugated annexin 1 targets tumor vasculature against P-gp mediated multidrug resistance |
Bioconjug Chem |
2015 |
26(8):1702-12 |
| Zhao Q, Yue J, Zhang C, Gu X,, Xu L |
Inactivation of M2 AChR/NF-κB signaling axis reverses epithelial-mesenchymal transition (EMT) and suppresses migration and invasion in non-small cell lung cancer (NSCLC) |
Oncotarget |
2015 |
6(30):29335-46 |
| Huang M, Hu M, Song Q, Song H, Huang J, Gu X, Wang X, Chen J, Kang T, Feng X, Jiang D, Zheng G,, Gao X |
GM1-Modified Lipoprotein-like Nanoparticle: Multifunctional Nanoplatform for the Combination Therapy of Alzheimer's Disease |
ACS Nano |
2015 |
9(11):10801-16 |
| Yu F, Gong P, Hu Z, Qiu Y, Cui Y, Gao X,, Li J. |
Cu (II) enhances the effect of Alzheimer’s amyloid-β peptide on microglial activation |
J Neuroinflammation |
2015 |
12:122 |
| Xu J, Zhao H, Zheng Z, Wang Y, Niu Y, Wang H, Xu J, Lu Y, |
Structural determinants for the interactions between muscarinic toxin 7 and muscarinic acetylcholine receptors |
J Mol Recognit |
2015 |
28(4):239-52 |
| Liu YR, Guan YY, Luan X, Lu Q, Wang C, Liu HJ, Gao YG, Yang SC, Dong X,, Fang C. |
Delta-like ligand 4-targeted nanomedicine for antiangiogenic cancer therapy |
Biomaterials |
2015 |
42:161-71 |
| Gong Y, Li X, Kang L, Xie Y, Rong Z, Wang H, Qi H, |
Simultaneous determination of endocannabinoids in murine plasma and brain substructures by surrogate-based LC–MS/MS: Application in tumor-bearing mice |
J Pharm Biomed Anal |
2015 |
111:57-63 |
| Li B, Li H, Bai Y, Kirschner-Schwabe R, Yang JJ, Chen Y, Lu G, Tzoneva G, Ma X, Wu T, Li W, Lu H, Ding L, Liang H, Huang X, Yang M, Jin L, Kang H, Chen S, Du A, Shen S, Ding J,, Chen J, von Stackelberg A, Gu L, Zhang J, Ferrando A, Tang J, Wang S, Zhou BB |
Negative feedback-defective PRPS1 mutants drive thiopurine resistance in relapsed childhood ALL |
Nat Med |
2015 |
21(6):563-71 |
| Wang X, Gu X, Song H, Song Q, Gao X, Lu Y, |
Phenylmethanesulfonyl fluoride pretreatment stabilizes plasma lipidome in lipidomic and metabolomic analysis |
Anal Chim Acta |
2015 |
893:77-83 |
| Sun F, Ding XP, An SM, Tang YB, Yang XJ, Teng L, Zhang C, Shen Y,, Zhu L |
Adrenergic DNA damage of embryonic pluripotent cells via β2 receptor signalling. |
Sci Rep |
2015 |
5:15950 |
| Sun F, Yang XJ, Lv HY, Tang YB, An SM, Ding XP, Li WB, Teng L, Shen Y,, Zhu L |
β2‐adrenoreceptor–mediated proliferation inhibition of embryonic pluripotent stem cells |
J Cell Physiol |
2015 |
230(11):2640-6 |
| Zhao WS, Wang J, Ma XJ, Yang Y, Liu Y, Huang LD, Fan YZ, Cheng XY,, Wang R, Yu Y |
Relative motions between left flipper and dorsal fin domains favour P2X4 receptor activation |
Nat Commun |
2014 |
5:4189-5189 |
| Song Q, Huang M, Yao L, Wang X, Gu X, Chen J, Chen J, Huang J, Hu Q, Kang T, Rong Z, Qi H, Zheng G,, Gao X. |
Lipoprotein-based nanoparticles rescue the memory loss of mice with Alzheimer's disease by accelerating the clearance of amyloid-beta. |
ACS Nano |
2014 |
8(3):2345-59 |
| Hu Z, Yu F, Gong P, Qiu Y, Zhou W, Cui Y, Li J, |
Subneurotoxic copper(II)-induced NF-κB-dependent microglial activation is associated with mitochondrial ROS |
Toxicol Appl Pharmacol |
2014 |
276(2):95-103 |
| Yao L, Song Q, Bai W, Zhang J, Miao D, Jiang M, Wang Y, Shen Z, Hu Q, Gu X, Huang M, Zheng G, Gao X, Hu B, Chen J, |
Facilitated brain delivery of poly (ethylene glycol)-poly (lactic acid) nanoparticles by microbubble-enhanced unfocused ultrasound |
Biomaterials |
2014 |
35(10):3384-95 |
| Tan PP, Yuan HH, Zhu X, Cui YY, Li H, Feng XM, Qiu Y,, Zhou W. |
Activation of muscarinic receptors protects against retinal neurons damage and optic nerve degeneration in vitro and in vivo models |
CNS Neurosci Ther |
2014 |
20(3):227-36 |
| Hou LN, Xu JR, Zhao QN, Gao XL, Cui YY, Xu J, Wang H, |
A New Motif in the N-Terminal of Acetylcholinesterase Triggers Amyloid-β Aggregation and Deposition |
CNS Neurosci Ther |
2014 |
20(1):59-66 |
| Shao BY, Xia Z, Xie Q, Ge XX, Zhang WW, Sun J, Jiang P, Wang H, Le WD, Qiu ZB, Lu Y, |
Meserine, a novel carbamate AChE inhibitor, ameliorates scopolamine-induced dementia and alleviates amyloidogenesis of APP/PS1 transgenic mice |
CNS Neurosci Ther |
2014 |
20(2):165-71 |
| Teng L, Tang YB, Sun F, An SM, Zhang C, Yang XJ, Lv HY, Lu Q, Cui YY, Hu JJ, Zhu L, |
Non-neuronal release of gamma-aminobutyric Acid by embryonic pluripotent stem cells. |
Stem Cells Dev |
2013 |
22(22):2944-53 |
| Song Q, Wang X, Hu Q, Huang M, Yao L, Qi H, Qiu Y, Jiang X, Chen J,, Gao X |
Cellular internalization pathway and transcellular transport of pegylated polyester nanoparticles in Caco-2 cells |
Int J Pharm |
2013 |
445(1-2):58-68 |
| Liu T, Xia Z, Zhang WW, Xu JR, Ge XX, Li J, Cui Y, Qiu ZB, Xu J, Xie Q, Wang H, |
Bis(9)-(-)-nor-meptazinol as a novel dual-binding AChEI potently ameliorates scopolamine-induced cognitive deficits in mice |
Pharmacol Biochem Behav |
2013 |
104:138-43 |
| Liu CX, Yin QQ, Zhou HC, Wu YL, Pu JX, Xia L, Liu W, Huang X, Jiang T, Wu MX, He LC, Zhao YX, Wang XL, Xiao WL,, Zhao Q, Zhou AW, Wang LS, Sun HD, Chen GQ |
Adenanthin targets peroxiredoxin I and II to induce differentiation of leukemic cells |
Nat Chem Biol |
2012 |
8(5):486-93 |
| Ge XX, Wang XL, Jiang P, Xie Y, Jiang T, Rong ZX, Zhang QZ, Xie Q, Qiu ZB, Wang H, |
Determination of Bis(9)-(-)-Meptazinol, a bis-ligand for Alzheimer's disease, in rat plasma by liquid chromatography-tandem mass spectrometry: application to pharmacokinetics study |
J Chromatogr B |
2012 |
881-882:126-30 |
| Wang Y, Xia Z, Xu JR, Wang YX, Hou LN, Qiu Y, |
α-Mangostin, a polyphenolic xanthone derivative from mangosteen, attenuates β-amyloid oligomers-induced neurotoxicity by inhibiting amyloid aggregation. |
Neuropharmacology |
2012 |
62(2):871-81 |
| Xia H, Gao X, Gu G, Liu Z, Hu Q, Tu Y, Song Q, Yao L, Pang Z, Jiang X, Chen J, |
Penetratin-functionalized PEG-PLA nanoparticles for brain drug delivery. |
Int J Pharm |
2012 |
436(1-2):840-50. |
| Song Q, Yao L, Huang M, Hu Q, Lu Q, Wu B, Qi H, Rong Z, Jiang X, Gao X, Chen J, |
Mechanisms of transcellular transport of wheat germ agglutinin-functionalized polymeric nanoparticles in Caco-2 cells |
Biomaterials |
2012 |
33(28):6769-82 |
| Zheng W, Li J, Qiu Z, Xia Z, Li W, Yu L, Chen H, Chen J, Chen Y, Hu Z, Zhou W, Shao B, Cui Y, Xie Q, |
Novel bis-(-)-nor-meptazinol derivatives act as dual binding site AChE inhibitors with metal-complexing property. |
Toxicol Appl Pharmacol |
2012 |
264(1):65-72. |
| Peng L, Jiang T, Rong Z, Liu T, Wang H, Shao B, Ma J, Yang L, Kang L, Shen Y, Li H, Qi H, |
Surrogate based accurate quantification of endogenous acetylcholine in murine brain by hydrophilic interaction liquid chromatography-tandem mass spectrometry. |
J Chromatogr B |
2011 |
879(32):3927-31 |
| Qiu Y, Wang Y, Law PY,, Loh HH. |
Cholesterol regulates micro-opioid receptor-induced beta-arrestin 2 translocation to membrane lipid rafts. |
Mol Pharmacol. |
2011 |
80(1):210-8 |
| Gao X, Yao L, Song Q, Zhu L, Xia Z, Xia H, Jiang X, Chen J, |
The association of autophagy with polyethylenimine-induced cytotoxity in nephritic and hepatic cell lines. |
Biomaterials |
2011 |
32(33):8613-25. |
| Jiang T, Rong Z, Peng L, Chen B, Xie Y, Chen C, Sun J, Xu Y, Lu Y, |
Simultaneous determination of citalopram and its metabolite in human plasma by LC-MS/MS applied to pharmacokinetic study. |
J Chromatogr |
2010 |
878(5-6):615-9 |
| Cui Y, Devillier P, Kuang X, Wang H, Zhu L, Xu Z, Xia Z, Zemoura L, Advenier C, |
Tiotropium reduces lung inflammation in a model of chronic gastro-oesophageal reflux. |
Eur Respir J. |
2010 |
35(6):1370-6 |
| Yu DH, Lu Q, Xie J, Fang C, |
Peptide-conjugated biodegradable nanoparticles as a carrier to target paclitaxel to tumor neovasculature |
Biomaterials |
2010 |
31(8):2278-2292 |
| Liu F, Fang C, Ye X, Lu Q, Yu DH, Zhang WW, Qi H, Xie J, Lieber A, |
Anti-4-1BB scFv immunogene therapy and low dose cyclophosphamide exhibit a synergistic antitumor effect in established murine lung tumors |
Cancer Biol Ther |
2009 |
8(8):707-713 |
| Qi H, Ma J, Liu YM, Yang L, Peng L, Wang H, |
Allostatic tumor-burden induces depression-associated changes in hepatoma-bearing mice. |
J Neurooncol |
2009 |
94(3):367-372 |
| Zhu X, Zhou W, Cui YY, Zhu L, Li J, Xia Z, Shao B, Wang H, |
Muscarinic activation attenuates abnormal processing of beta-amyloid precursor protein induced by cobalt chloride-mimetic hypoxia in retinal ganglion cells |
Biochem Biophys Res Commun |
2009 |
384(1):110-113 |
| Lu Q, Yu DH, Fang C, Liu F, Ye X, Zhao Y, Qin J, Guo XK, Liang M, Hu F, |
Influence of E3 region on conditionally replicative adenovirus mediated cytotoxicity in hepatocellular carcinoma cells. |
Cancer Biol Ther |
2009 |
8(12):1125-1132 |
| Miezan Ezoulin JM, Shao BY, Xia Z, Xie Q, Li J, Cui YY, Wang H, Dong CZ, Zhao YX, Massicot F, Qiu ZB, Heymans F, |
Novel piperazine derivative PMS1339 exhibits tri-functional properties and cognitive improvement in mice |
Int J Neuropsychopharmacol |
2009 |
12(10):1409-1419 |
| Fu J, Feng X, Yuan H, Yan L, Kuang X, Xia Z, Gao X, Yu C, Lu Y, |
Study of ocular pharmacokinetics of in situ gel system for S(-)-satropane evaluated by microdialysis |
J Pharm Biomed Anal |
2008 |
48(3):840-843 |
| Xie Q, Wang H, Xia Z, Lu MY, Zhang WW, Wang XH, Fu Wei, Tang Y, Sheng W, Li W, Zhou W, Zhu X, Qiu ZB, |
Bis-(-)-nor-meptazinols as novel nanomolar cholinesterase inhibitors with high inhibitory potency on Amyloid-β aggregation. |
J Med Chem |
2008 |
51(7):2027-2036 |
| Ren Z, Ye X, Fang C, Lu Q, Zhao Y, Liu F, Liang M, Hu F, |
Intratumor injection of oncolytic adenovirus expressing HSP70 prolonged survival in melanoma B16 bearing mice by enhanced immune response.immunocompetent mice. |
Cancer Biol Ther. |
2008 |
7(2):191-195 |
| Song MK, Liu H, Jiang HL, Yue JM, Hu GY, |
Discovery of talatisamine as a novel specific blocker for the delayed rectifier K(+) channels in rat hippocampal neurons. |
Neuroscience. |
2008 |
155(2):469-475 |
| Liu F, Lu Q, Ye X, Fang C, Zhao Y, Liang M, Hu F, Lieber A, |
Cancer gene therapy of adenovirus-mediated anti-4-1BB scFv in immunocompetent mice. |
Cancer Biol Ther. |
2008 |
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Quantum dots bearing lectin-functionalized nanoparticles as a platform for in vivo brain imaging |
Bioconjug Chem. |
2008 |
19(11):2189-2195 |
| Gao X, Wang T, Wu B, Chen J, Chen J, Yue Y, Dai N,, Jiang X |
Quantum dots for tracking cellular transport of lectin-functionalized nanoparticles. |
Biochem Biophys Res Commun |
2008 |
377(1):35-40 |
| Fang C, Liu Y, Ye X, Rong ZX, Feng XM, Jiang CB, |
Synergistically enhanced transdermal permeation and topical analgesia of tetracaine gel containing menthol and ethanol in experimental and clinical studies. |
Eur J Pharm Biopharm. |
2008 |
68(3):735-740 |
| Li J, Shao B, Zhu L, Cui Y, Dong C, Miezan Ezoulin JM, Gao X, Ren Q, Heymans F, |
PMS777, A Bis-interacting Ligand for PAF Receptor Antagonism and AChE Inhibition, Attenuates PAF-induced Neurocytotoxicity in SH-SY5Y Cells. |
Cell Mol Neurobiol |
2008 |
28(1):125-136 |
| Zhou W, Zhu X, Zhu L, Cui YY, Wang H, Qi H, Ren QS, |
Neuroprotection of Muscarinic Receptor Agonist Pilocarpine Against Glutamate-induced Apoptosis in Retinal Neurons |
Cell Mol Neurobiol |
2008 |
28(2):263-275 |
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