上海市消化道微生態(tài)及相關(guān)重大疾病重點(diǎn)實(shí)驗(yàn)室
上海交通大學(xué)消化疾病研究與臨床轉(zhuǎn)化中心
上海交通大學(xué)消化疾病研究與臨床轉(zhuǎn)化中心成立于2020年9月，2022年4月經(jīng)上海市科委批準(zhǔn)建設(shè)上海市消化道微生態(tài)及相關(guān)重大疾病重點(diǎn)實(shí)驗(yàn)室，由孟祥軍教授擔(dān)任中心及重點(diǎn)實(shí)驗(yàn)室主任。實(shí)驗(yàn)室依托上海交通大學(xué)醫(yī)學(xué)院、上海交通大學(xué)醫(yī)學(xué)院附屬第九人民醫(yī)院，匯聚了一批消化學(xué)科優(yōu)秀中青年科學(xué)家。 近年來(lái)承擔(dān)多項(xiàng)國(guó)自然、上海市科委重點(diǎn)項(xiàng)目、上海市浦江人才項(xiàng)目及上海市科創(chuàng)揚(yáng)帆人才計(jì)劃等課題，在國(guó)際知名雜志JCI, Gastroenterology, Cell Death & Differentiation, Nature Biomedical Engineering, Oncogene, JBC等發(fā)表論文多篇。
實(shí)驗(yàn)室致力于研究臨床治療實(shí)踐中的科學(xué)問(wèn)題，通過(guò)深入、系統(tǒng)的基礎(chǔ)科研工作，實(shí)現(xiàn)機(jī)制研究與臨床轉(zhuǎn)化并重，推動(dòng)消化道微生態(tài)與重大疾病研究的全面深化，闡明消化道微生態(tài)對(duì)消化系、內(nèi)分泌代謝、心血管、神經(jīng)系統(tǒng)等相關(guān)重大疾病發(fā)生發(fā)展的影響及相關(guān)診斷治療的分子機(jī)理等問(wèn)題，揭示消化道“微生物-代謝-內(nèi)分泌-免疫”的調(diào)控網(wǎng)絡(luò)與互作關(guān)系，促進(jìn)消化道微生態(tài)與重大疾病研究向臨床診療方向轉(zhuǎn)化，最終實(shí)現(xiàn)造福病患的目的。
實(shí)驗(yàn)室聯(lián)系人
姓名：姚晗
電話：18116207970
郵箱：[email protected]
Shanghai Key Laboratory of Gut Microecology and Associated Diseases
The Digestive Disease Research and Clinical Transformation Center, SJTU
The Digestive Disease Research and Clinical Transformation Center of Shanghai Jiao Tong University was founded in September 2020. In April 2022, it was approved by Shanghai Commission of Science and Technology to establish Shanghai Key Laboratory of Gut Microecology and Associated Diseases, with Professor Meng Xiangjun as the director. Supported by Shanghai Jiao Tong University School of Medicine and Shanghai Ninth People's Hospital, the laboratory has attracted a number of excellent scientists and young talents in the field of digestion diseases. In recent years, we have successfully applied multiple grants from National Natural Science Foundation of China, Major Program of Shanghai Committee of Science and Technology including Shanghai Pujiang Talent Project, Shanghai Science and Technology Innovation Talents Program, et, al., and published high quality articles in international academic journals, such as JCI, Gastroenterology, Cell Death & Differentiation, Nature Biomedical Engineering, Oncogene, JBC. etc.
The laboratory is dedicated to the study of scientific questions from clinical therapeutic practice, put equal emphasis on mechanism research and clinical transformation through in-depth and systematic basic scientific research work, promoting the researches of gastrointestinal microecology and associated major diseases. The laboratory focuses on exploring molecular mechanism of how gut microorganisms affect the occurrence, development, diagnosis and treatment of associated major diseases, including endocrine metabolic disease, cardiovascular disease, nervous system related diseases, etc., revealing regulation network and mutual relationship of “gut microorganism-metabolism-endocrine-immune”. We strive to elucidate the driving effect of digestive tract microecology on associated diseases and their microenvironment remodeling, and promote the transformation of basic research on digestive tract microecology and associated diseases to clinical diagnosis and treatment, ultimately achieving the goal of benefiting patients.
Contact:
Dr. Han Yao
Phone number：18116207970
E-mail：[email protected]
