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朱泳璋

作者:   發(fā)布時間 :2021年04月23日








姓名:朱泳璋

職稱:病原微生物學副教授 / 微生物檢驗技術副主任技師

畢業(yè)院校:清華大學北京協(xié)和醫(yī)學院博士,、上海交通大學醫(yī)學院病原生物學博士后,、康奈爾大學獸醫(yī)學院人畜共患病實驗室訪問學者      

籍貫:湖南岳陽   

聯(lián)系電話:021-63846590轉(zhuǎn)776974

工作單位:上海交通大學醫(yī)學院全球健康學院

郵箱:[email protected]



教育經(jīng)歷

1998.09-2002.07  云南大學生命科學學院 國家生物學基地班  微生物學 學士

2002.09-2007.07  清華大學-北京協(xié)和醫(yī)學院 醫(yī)學生物學研究所 碩博連讀 遺傳學雙博士

2007.09-2009.09  病原生物學教研室 上海交通大學醫(yī)學院  病原生物學博士后


工作經(jīng)歷

2011.03-2017.07  病原生物學教研室 上海交通大學醫(yī)學院   病原微生物學副教授

2014.11-2015.11  動物醫(yī)學院人畜共患病實驗室  康奈爾大學  訪問學者

2017.08-2019.03  抗生素研究所 復旦大學附屬華山醫(yī)院 副教授

2020.06-2020.11  衛(wèi)生檢疫所P3實驗室 廣州海關技術中心 檢驗副主任技師

2020.12-至今    全球健康學院 上海交通大學醫(yī)學院國家熱帶病研究中心  病原微生物學副教授


教學工作

  • 主要承擔上交醫(yī)以下課程教學工作:“病原生物學”、“病原基因組”,、“醫(yī)學微生物學研究進展”,、 “全球健康與全健康”;作為編委參加“醫(yī)學微生物學”和“病原生物學”多本國家級醫(yī)學教材編寫,;

  • 榮獲上海交通大學醫(yī)學院基礎醫(yī)學院2016年度青年教師授課比賽一等獎,;獲2023,、2024年上交醫(yī)PBL案例大賽優(yōu)勝獎;

 

社會學術任職

  1. 中國微生物學會人獸共患病病原學專委會委員      

  2. 中國生物工程學會噬菌體專委會委員

  3. 中國微生物學會醫(yī)學微生物學與免疫學專委會青年學組委員

  4. 全國公共衛(wèi)生與預防醫(yī)學名詞編寫委員會熱帶醫(yī)學名詞編寫分委員會委員

  5. 教育部基礎醫(yī)學“101計劃”核心教材-《基礎醫(yī)學核心實踐與創(chuàng)新研究》編委

  6. 上海預防醫(yī)學會微生態(tài)學專委會委員            

  7. 上海微生物學會微生物組專委會委員

  8. 《中華地方病學雜志》和《中國人獸共患病學報》編輯委員會編委

 

主持科研項目

  1. 國家重點研發(fā)計劃-中英政府間旗艦挑戰(zhàn)計劃項目“基于全健康的中英細菌耐藥動態(tài)變化規(guī)律及驅(qū)動因素研究”子課題“多重耐藥病原菌在全健康系統(tǒng)的耐藥動態(tài)變化規(guī)律”負責人(2024YFE0199000):

  2. 國家自然科學基金:鉤端螺旋體黃疸出血群有毒株和無毒株毒力進化機制探索(30900051)

  3. 省自然科學基金:基于基因組學和蛋白質(zhì)組學方法篩選百日咳疫苗新抗原(BK2010158)

  4. 國家博士后基金:鉤端螺旋體秋季血清群強毒株和弱毒株全基因組測序及比較基因組學研究(20080430655)

 

主要研究方向

重要耐藥菌和耐藥基因在人-動物-環(huán)境多界面流行傳播模式和相互作用機制


具體研究內(nèi)容

崇明島全健康系統(tǒng)AMR監(jiān)測范式,,以及上海重要伴侶動物犬貓病原譜和高風險耐藥質(zhì)??缃缑媪餍袀鞑ヒ?guī)律研究等。以項目負責人主持國家重點研發(fā)計劃子課題(中英政府間旗艦挑戰(zhàn)計劃項目),、國家自然科學青年基金,、省自然科學基金和國家博士后基金等多項省部級課題,2018年以來以第一作者或通訊作者發(fā)表包括9篇中科院一區(qū)文章在內(nèi)的SCI論文19篇,,影響因子超過10分以上有8篇,,累計影響因子超過150,包括Journal of Hazardous Materials,、Enviroment International,、 Emerging Microbes & infections、Sci Total Environ,、Infectious Disease of Poverty,、mSystems、Communications Biology和One Health等,。

代表性論著

  1. Yiwen Chen, Min Li, Bingqing Sun, Luming Xia, Yifei Zhang, Jun Feng, Min Chen, Zile Cheng, Chao Lv, Weiye Chen, Jiewen Huang, Qingtian Li, Yu Zhang, Jun Shang, Ying Cao, Tianyu Wang, Yanqi Liu, Mengmeng Wang, Bin Zhang, Xiaokui Guo*, Shixin Huang*, Zhu YZ*(corresponding author). Companion Animals as Sources of Hazardous Critically Important Antimicrobial-Resistant Escherichia coli : Genomic Surveillance in Shanghai.  Journal of Hazardous Materials (newly accepted).

  2. Zile Cheng, Yiwen Chen, Min Li, Chao Lv, Nan Zhou, Weiye Chen, JieWen Huang, QingTian Li, Zijing Gao, Xuesong Feng, Li Shi, YuFeng Yao*, Xiaokui Guo*, Zhu YZ*(corresponding author). An Unusual 'Gift' from Humans: Third-Generation Cephalosporin-Resistant Enterobacterales in migratory birds along the East Asian-Australasian Flyway. Environment International. 2025 Feb 12:197:109320. doi: 10.1016/j.envint.2025.109320.

  3. Dongling Long, Min Li, Lingchao Ma, Jiewen Huang, Chao Lv, Yiwen Chen, Zile Cheng, Chang Liu, Huitao Huang, Xiaokui Guo, Chao Yang*, Zhu YZ*(corresponding author). Epidemiological and genetic charateristics of Vibrio vulnificus from diverse sources in China during 2012-2023. Commun Biol. 2025 Jan 4;8(1):9.doi: 10.1038/s42003-024-07426-5.

  4. Chao Lv, Jun Leng d, Minjian Qian, Bingqing Sun, HuiPing Ye, Min Li, Nan Zhou, Zile Cheng, Yiwen Chen, Xiaokui Guo, Jun Shang, Li Zhang*, Zhu YZ *(corresponding author). Antimicrobial resistance in Escherichia coli and Staphylococcus aureus at human-animal interfaces on Chongming Island, Shanghai: A One Health perspective. One Health Volume 19, December 2024, 100910.

  5. Huang J, Zhou N, Cheng Z, Chen Y, Li M, Lv C, Guo X, Li Q, Yao Y*, Dong K*, Zhu YZ *(corresponding author). Chromosomally located blaCMH in Enterobacter cloacae complex across human-bird-environment interfaces: A one-health perspective. Sci Total Environ 2024 Sep 23:954:176486.

  6. Chen W, Chen Y, Cheng Z, Chen Y, Lv C, Ma L, Zhou N, Qian J, Liu C, Li M*, Guo X*, Zhu YZ *(corresponding author). Global patterns of syphilis, gonococcal infection, typhoid fever, paratyphoid fever, diphtheria, pertussis, tetanus, and leprosy from 1990 to 2021: findings from the Global Burden of Disease Study 2021. Infect Dis Poverty 2024 Sep 13;13(1):66.

  7. Jiewen Huang, Chao Lv , Min Li , Tanvir Rahman , Yung-Fu Chang , Xiaokui Guo , Zhen Song , Yanan Zhao , Qingtian Li*, Peihua Ni* , Zhu YZ *(corresponding author). Carbapenem-resistant Escherichia coli exhibit diverse spatiotemporal epidemiological characteristics across the globe.  Communications Biology 7: 51 (2024).

  8. Min Li, Haoran Zhang, Wengang Zhang, Ying Cao, Bingqing Sun, et al, Xiaokui Guo, Jun Shang*, Shixin Huang*, Zhu YZ *(corresponding author). One global disseminated 193 kb high-risk hybrid plasmid harboring tet(X4), mcr or blaNDM threatening public health.  Sci Total Environ 2023 Mar 14;876:162807.

  9. Chang C, Guo W, Yu X, Guo C, Zhou N, Guo X, Huang RL*, Li Q*, Zhu Y*(corresponding author). Engineered M13 phage as a novel therapeutic bionanomaterial for clinical applications: From tissue regeneration to cancer therapy. Mater Today Bio 2023 Mar 24;20:100612.

  10. Chao Lv, Jun Shang, Wengang Zhang, Bingqing Sun, Min Li, Chaoyi Guo, Nan Zhou, Xiaokui Guo*, Shixin Huang*, Zhu YZ *(corresponding author). Dynamic antimicrobial resistant patterns of Escherichia coli from healthy poultry and swine over 10 years in Chongming Island, Shanghai. Infect Dis Poverty 2022 Sep 16;11(1):98.

  11. Nan Zhou, Zile Cheng, Xiaoxi Zhang, Chao Lv, Chaoyi Guo, Haodong Liu, Ke Dong, Yan Zhang, Chang Liu, Yung-Fu Chang, Sheng Chen, Xiaokui Guo*, Xiao-Nong Zhou*, Min Li*,  Zhu YZ* (corresponding author). Global antimicrobial resistance: a system-wide comprehensive investigation using the Global One Health Index. Infect Dis Poverty 2022 Aug 23;11(1):92.

  12. Zhu Y (the first author), Shi L, Zeng Y, Piao D, Xie Y, Du J, Gao M, Gao W, Tian J, Yue J, Li M, Guo X, Yao Y*, Kang Y*. Key immunity characteristics of diverse stages of brucellosis in rural population from Inner Mongolia, China. Infect Dis Poverty 2022 Jun 4;11(1):63.

  13. Hongye Wang, Dongshan Yan, Ya Li, Yanfei Gong, Yulin Mai, Bingxiang Li, Xiaoyong Zhu, Xinrui Wan, Liyun Xie, HuaKe Jiang, Min Zhang, Ming Sun*, Yufeng Yao*, Zhu YZ *(corresponding author). Clinical and antibody characteristics reveal diverse signatures of severe and non-severe SARS-CoV-2 patients. Infect Dis Poverty. 2022 Feb 2;11(1):15.

  14. Tinghua Li, Yan Zhang, Ke Dong, Chih-Jung Kuo, Chong Li, Yong-Qiang Zhu, Jinhong Qin, Qing-Tian Li, Yung-Fu Chang*, Xiaokui Guo*, Zhu YZ *(corresponding author). Isolation and Characterization of the Novel Phage JD032 and Global Transcriptomic Response during JD032 Infection of Clostridioides difficile Ribotype 078.  mSystems 2020 May 5;5(3):e00017-20.

  15. Cuicai Zhang, Jianmin Xu, Tinglan Zhang, Haiyan Qiu, Zhenpeng Li, Enmin Zhang, Shijun Li, Yung-Fu Chang, Xiaokui Guo*, Xiugao Jiang*, Zhu YZ *(corresponding author). Genetic Characteristics of Pathogenic Leptospira in wild small animals and livestock in Jiangxi Province, China, 2002-2015.  PLOS Neglected Tropical Diseases. June 24, 2019  10.1371/journal.pntd.0007513

  16. Xu-ming Li, Yao-xia Kang1, Liang Lin, En-Hou Jia, Dong-Ri Piao, Hai Jiang, Cui-Cai Zhang, Jin He*, Yung-Fu Chang*, Xiao-Kui Guo*, Zhu YZ *(corresponding author). Genomic Characterization Provides New Insights for Detailed Phage- Resistant Mechanism for Brucella abortus. Front Microbiol. 03 May 2019.

  17. Jiayu Wang, Zheng Teng, Wei Chu, Fanghao Fang, Xiaoqing Cui, Xiaokui Guo, Xi Zhang*, Bruce Thorley*, Zhu YZ *(corresponding author). The Emergence and Spread of One Coxsackievirus A16 Genogroup D Novel Recombinant Strain Causing a Clustering HFMD Outbreak in Shanghai, China, 2016.  Emerg Microbes Infect. 2018 Jul 18;7(1):131.

  18. Jiayu Wang, Zheng Teng, Xiaoqing Cui, Chongshan Li, Hao Pan, Yaxu Zheng, Shenghua Mao, Yuying Yang, Limeng Wu, Xiaokui Guo*, Xi Zhang*, Zhu YZ *(corresponding author).  Epidemiological and Serological Surveillance of Hand-Foot-and-Mouth Disease in Shanghai, China, 2012- 2016.  Emerg Microbes Infect. 2018 Jan 24;7(1):8.

 

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