姓名：胡沁沁 職稱：副研究員 碩士生導師
入選“2024年上海市東方英才計劃青年項目”
辦公室地址：上海市黃浦區(qū)重慶南路280號1號樓411室
辦公室電話：021-63846590轉(zhuǎn)776975
郵箱：[email protected]
教育經(jīng)歷（從本科開始）
2007年-2011年 陜西師范大學 食品科學與工程專業(yè)學士
2011年-2016年 浙江大學 生物系統(tǒng)工程專業(yè)博士 導師：李延斌
2014年-2016年 美國阿肯色大學 農(nóng)業(yè)與生物系統(tǒng)工程系 聯(lián)合培養(yǎng)
工作經(jīng)歷
2016年-2019年 復旦大學生物醫(yī)學研究院，博士后 合作導師：顧宏周
2019年-2021年 復旦大學生物醫(yī)學研究院,，助理研究員
2021年-2021年 上海交通大學醫(yī)學院全球健康學院,，助理研究員
2022年-至今 上海交通大學醫(yī)學院全球健康學院，副研究員
社會/學術任職和活動
Science in One Health 青年編委
Scientific Reports編委
Sensors期刊客座編輯
科研方向/主要研究內(nèi)容
功能核酸與生物傳感在疾病診斷,、食品安全的基礎及應用研究：
聚焦食源性風險因素現(xiàn)場監(jiān)測和重大疾病快速診斷,，開發(fā)新型分子診斷/生物傳感檢測方法，篩選功能核酸用于識別與鑒定疾病相關分子
科研項目
項目編號 |
項目類型 |
項目名稱 |
起止年月 |
備注 |
22474076 |
國家自然科學基金青年科學面上項目 |
基于DNA核酶“親和-催化”策略的細胞外囊泡特異性靶標發(fā)現(xiàn)與分析 |
2025.01-2028.12 |
項目負責人 |
82000270 |
國家自然科學基金青年科學基金項目 |
適配體-DNA納米自組裝靶向調(diào)控GTF2H4在心臟微血管內(nèi)皮細胞缺血再灌注損傷中的作用及分子機制 |
2021.01-2023.12 |
項目負責人 |
202340069 |
上海市衛(wèi)生健康委員會臨床專項 |
適配體-級聯(lián)放大生物傳感器用于快速檢測耐藥型TNBC外泌體的方法研究 |
2023.07-2026.06 |
項目負責人 |
TMSK-2021-114 |
轉(zhuǎn)化醫(yī)學國家重大科技基礎設施（上海）開放課題項目 |
級聯(lián)放大-適配體傳感器用于診斷耐藥型TNBC外泌體 |
2021.10-2023.10 |
項目負責人 |
2018110347 |
第11批中國博士后科學基金特別資助 |
耐藥型三陰性乳腺癌外泌體適體核酶篩選及生物傳感檢測 |
2018.09-2019.06 |
項目負責人 |
發(fā)表論文（格式：國標GB／T7714-2015）
Qinqin Hu#, Zongxuan Tong#, Ayimukedisi Yalikong#, Li-Ping Ge#,Qiang Shi, Xinyu Du, Pu Wang, Xi-Yu Liu, Wuqiang Zhan, Xia Gao, Di Sun, Tong Fu, Dan Ye, Jie Liu, Chunhai Fan, Yun-Shi Zhong*, Yi-Zhou Jiang*, Hongzhou Gu*. DNAzyme-Based Faithful Probing-and-Pulldown to Identify Candidate Biomarkers of Low Abundance. Nature Chemistry 2024, 16: 122-131.
Huimin Li, Leshan Xiu, Xiaokui Guo, Qinqin Hu*, Kun Yin*. Spatiotemporal dual-dimensional separation enables ultra-simple one-pot CRISPR-based molecular diagnostics, Chemical Engineering Journal, 2024, 482: 148872.
Fumin Chen, Chenang Lyu, Zhao Li, Leshan Xiu, Huimin Li, Yi Xie, Runzhen Cao, Qinqin Hu*, Kun Yin*. Fully Integrated Microfluidic Platform for Multiplexed Detection of Hunov by a Dynamic Confine-Space-Implemented One-Pot Rpa-Lamp System, Advanced Science, 2023, 2306612.
Si-Yu Gu, Fu-Min Chen, Chen-Sheng Zhang, Yi-Bin Zhou, Tian-Yun Li, Ne Qiang, Xiao-Xi Zhang, Jing-Shu Liu, Shu-Xun Wang, Xue-Chen Yang, Xiao-Kui Guo, Qin-Qin Hu*, Xiao-Bei Deng*, Le-Fei Han*. Assessing food security performance from the One Health concept: an evaluation tool based on the Global One Health Index. Infectious Diseases of Poverty, 2023, 12, 88.
Yawen He, Qinqin Hu, Samantha San, Tom Kasputis, Maria Gabriella Duarte Splinter, Kun Yin*, Juhong Chen*. CRISPR-based biosensors for human health: A novel strategy to detect emerging infectious diseases. TrAC Trends in Analytical Chemistry 2023, 168, 117342.
Fumin Chen#, Qinqin Hu#, Huimin Li, Yi Xie, Leshan Xiu, Yuqian Zhang, Xiaokui Guo*, Kun Yin*. Multiplex Detection of Infectious Diseases on Microfluidic Platforms. Biosensors, 2023, 13, 410.
Huimin Li#, Yi Xie#, Fumin Chen, Huiwen Bai, Leshan Xiu, Xiaonong Zhou, Xiaokui Guo*, Qinqin Hu*, Kun Yin*. Amplification-free CRISPR/Cas Detection Technology: Challenges, Strategies, and Perspectives. Chemical Society Reviews 2023, 52(1):361-382.
Qinqin Hu#; Zheyan Fang#; Junbo Ge*; Hua Li*. Nanotechnology for Cardiovascular Diseases. The Innovation 2022, 3(2): 100214.
Qinqin Hu#; Hua Li#; Lihua Wang; Hongzhou Gu*; Chunhai Fan*. “DNA Nanotechnology Enabled Drug Delivery systems.” Chemical Reviews. 2019, 119(10): 6459-6506.
Qinqin Hu#; Sheng Wang; Lihua Wang; Hongzhou Gu*; Chunhai Fan*. DNA Nanostructure-Based Systems for Intelligent Delivery of Therapeutic Oligonucleotides. Advanced Healthcare Materials. 2018, 7, 1-19.
Qinqin Hu#; Ronghui Wang; Hong Wang; Michael F. Slavik; Yanbin Li*. “Selection of Acrylamide-Specific Aptamers by a Quartz Crystal Microbalance Combined SELEX Method and Their Application in Rapid and Specific Detection of Acrylamide.” Sensors and Actuators B: Chemical 2018, 273, 220-227.
Qinqin Hu#; Yingchun Fu; Xiahong Xu; Zhaohui Qiao; Ronghui Wang;Ying Zhang; Yanbin Li*. “A Colorimetric Detection of Acrylamide in Potato Chips Based on Nucleohile-Initiated Thiol-Ene Michael Addition.” Analyst 2016, 141, 1136-1143.
Qinqin Hu#; Xiahong Xu; Yingchun Fu; Yanbin Li*. “Rapid methods for Detecting Acrylamide in Thermally Processed Foods: A Review.” Food Control 2015, 56, 135-146.
Qinqin Hu#; Xiahong Xu; Zhanming Li; Ying Zhang; Jianping Wang; Yingchun Fu; Yanbin Li*. “Detection of Acrylamide in Potato Chips Using a Fluorescent Sensing Method Based on Acrylamide Polymerization-Induced Distance Increase Between Quantum Dots.” Biosensors and Bioelectronics 2014, 54, 64-71.
Qinqin Hu#; Xiahong Xu; Zhanming Li; Ying Zhang; Yanbin Li*. “Rapid Detection of Acrylamide in Food Using a Fluorescent Sensing Method Based on Functional CdSe/ZnS Quantum Dots.” IEEE Sensors 2013, 414-417.
Yi Xie, Huimin Li, Fumin Chen, Srisruthi Udayakumar, Khyati Arora, Hui Chen, Yang Lan, Qinqin Hu, Xiaonong Zhou, Xiaokui Guo*, Leshan Xiu*, and Kun Yin*. Clustered Regularly Interspaced short palindromic repeats-Based Micro?uidic System in Infectious Diseases Diagnosis: Current Status, Challenges, and Perspectives. Advanced Science 2022, 2204172.
Zongxuan#, Tong; Qinqin Hu; Hongzhou Gu*. “Deoxyribozymes: Selection, Biosensing and Outlook.” Chemical Journal of Chinese Universities-Chinese 2020, 41 (11), 2345-2355.
Hong Wang#*; Lijun Wang; Qinqin Hu; Ronghui Wang; Yanbin Li; Michael Kidd. “Rapid and Sensitive Detection of Campylobacter jejuni in Poultry Products Using a Nanoparticle-Based Piezoelectric Immunosensor Integrated with Magnetic Immunoseparation.” Journal of Food Protection 2018, 81 (8), 1321–1330.
Zhuo Zhao#; Lizhou Xu; Qinqin Hu; Ronghui Wang; Hong Wang; Yanbin Li*. “A portable and automatic biosensing instrument for simultaneous detection of foodborne pathogens using nanobead-based magnetic separation and quantum dot-labeled fluorescent measurement.” 2016 ASABE Annual International Meeting 162461406. (doi:10.13031/aim.20162461406)
Huiyan Li#; Fangfei Yin; Xinyi Li; Wannan Jia; Jia Ding; Li Zhang; Zhonghua Wang; Qinqin Hu; Jieliang Zuo; Huliang Jia; Li hua Wang; Chunhai Fan*; Hongzhou Gu*; Jian Wu.* “Novel aptasensor-based assay of sonic hedgehog ligand for detection of portal vein invasion of hepatocellular carcinoma” Biosensors and Bioelectronics 2021, 174, 112738.
英文：
Name：Qinqin Hu
Degree：Ph.D.
Title：Associate Researcher/Professor
Email Address: [email protected]
Office Address: Rm 412, Building 1, 280 South Chongqing Road, Shanghai
Office Tel: 021-63846590 * 776974
Education：
2007-2011, B.D. Shaanxi Normal University (Food science and technology).
2011-2016, Ph.D. Zhejiang University, Biosystem engineering, supervisor: Prof. Yanbin Li.
2014-2016, Joint Ph.D. student, University of Arkansas (Agricultural and biological system engineering, CSC funding)
Appointments：
2016-2019, Institutes of Biomedicine, Fudan University, Postdoc training, supervisor: Prof. Hongzhou Gu
2019-2021, Institutes of Biomedicine, Fudan University, Assistant Researcher
2021-2021, Shanghai Jiao Tong University School of Medicine, Assistant Researcher
2022-Present, Shanghai Jiao Tong University School of Medicine, Associate Researcher/Professor
Academic Participation and Activities：
Guest Editor of Sensors
Editor of Science in One Health
Research Interest：
Dr. Qinqin Hu is interested in the basic and application research on developing biosensors and functional nucleic acids for disease diagnostic and food safety. She especially focuses on 1) novel molecular diagnostic techniques (CRISPR/Cas-based) and nano/optical biosensors for food hazards surveillance and rapid disease diagnosis; 2) In vitro selection of functional nucleic acids including DNAzymes or aptamers for the identification of potential disease-related molecules.
醫(yī)學院主頁
