E-mail address：[email protected]
Research Direction：The function and mechanisms of cell death and inflammation in human diseases
Education：
2007.9-2011.6 School of life sciences, Huzhou University, Bachelor of Bioengineering
2011.9-2014.6 College of forestry and biotechnology, Zhejiang agriculture and Forestry University, Master
2018.9-2023.6 Biomedical Research Institute of Fudan University,Doctoral candidate in Chemical Biology
Work Experience：
2015.6-2018.8 Biomedical Research Institute of Fudan University, Research assistant
Publications:
1. Maohua Yang 1 , Yegen Tang 1 , Jingwei Weng*, Zhijun Liu*, Wenning Wang*. The Role of
Calcium in Regulating the Conformational Dynamics of D-Galactose/D-Glu cose-Binding
Protein Revealed by Markov State Model Analysis. Journal of Chemical Information and
Modeling. 2021, 61, 891-900. ( 1First two authors contributed equally)
2. Chenxiao Jiang 1 ,Yegen Tang 1 ,Lulu Ding 1 ,Renke Tan,Yu Ding*,Jianwei Liu*,Yongjun
Dang*.Targeting the N Terminus of eIF4AI for Inhibition of Its Catalytic Recycling.Cell
Chemical Biology.2019,26,1417-1426.
3. Lei JT, Qi RX, Yegen Tang, Wang WN, Wei GH, Nussinov R, et al. Conformational
stability and dynamics of the cancer-associated isoform 133p53 are modulated by p53
peptides and p53-specific DNA. Faseb J. 2019;33(3):4225-35.
4. Yegen Tang, Maohua Yang,，Jingwei Weng*, Zhijun Liu*, Wenning Wang*.Conformational
Dynamics of Holo-GGBP Revealed by Experimental and Computational Analysis. (in
preparation)
5. Yegen Tang, Maohua Yang,，Zhijun Liu*, Wenning Wang*.Multiple conformational states and
Conformational Dynamics regulate the GlucoseGalactose binding protein.(under review)
Participated projects:
1. National Basic Research Program of China(973 Program),，Construction of SOC1
regulatory network of flower forming key gene of Phyllostachys pubescens
2. National Natural Science Foundation of China,，Usp9x regulates protein translation
initiation through deubiquitination eIF4B and its application in tumor targeted therapy
3. National Natural Science Foundation of China,，Development of a new AFM optical
composite imaging system and its role in cardiomyocyte mechanical properties and
drug screening National Natural Science Foundation of China,，Study on conformational
changes and transport mechanism of vitamin B12 input protein BtuCD
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