Location:
Yong Han Young Investigator
Email: [email protected]
Research area：Neural mechanisms of sleep regulating energy metabolism and emotion-related diseases
Education experience
2009-2015 Zhejiang University, PhD
2004-2009 Taishan Medical College, MB
Work experience
2023.07- Now Songjiang Research Institute, Shanghai Jiao Tong University School of Medicine, Young Investigator
2023.01-2023.06 Baylor College of Medicine, Instructor
2015.09-2022.12 Baylor College of Medicine, Postdoctoral Associate
Yong Han, an independent PI and was awarded as an Overseas Shanghai Youth Leading Talent. Dr. Han graduated in 2009 with a Bachelor of Medicine degree from Taishan Medical College. In 2015, he obtained his Ph.D. in Neuroscience from Institute of Neuroscience, Zhejiang University. In the same year, he joined Baylor College of Medicine in the United States for postdoctoral training and was appointed as an Instructor in the early 2023. In July 2023, he began his position at the Songjiang Research Institute, Shanghai Jiao Tong University School of Medicine. Dr. Han’s lab studies neural circuits that regulate innate behaviors such as feeding, emotion, and sleep. His research results have been published as the first author in Nature Communications, Science Advances, Molecular Psychiatry, Current biology, eLife and other journals. He also participated in writing the book Neural Regulation of Metabolism. He has won the Hsiang-tung Chang Excellent Graduate Student Paper Award, Outstanding Doctoral Dissertation of Zhejiang University, Outstanding Graduate of Zhejiang University, Award of the National Scholarship for Graduate Students, China Sleep Research Society Young Outstanding Thesis Award and CSRS-Philips Respironics Outstanding Young Investigators Award.
Yong Han
Dr. Han's research focuses on neural circuits regulating energy metabolism, feeding behavior, and sleep-wake cycles and other innate behaviors. His research findings, as the first author, have been published in journals such as Nature Communications, Science Advances, Molecular Psychiatry, Current Biology, eLife, and he has also contributed to the writing of the neurobiology book 'Neural Regulation of Metabolism.' He has received several awards, including Outstanding Ph.D. Thesis at Zhejiang University, Hsiang-tung chang Excellent Graduate Student Paper Award, Award of Honor for Graduate, Zhejiang University, Talent Award of Beijing Institutes of Life Science, Award of the National Scholarship for Graduate Students, and CSRS-Philips Respironics Outstanding Young Investigators Award.
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?Lu Miao Postdoctor
Email:[email protected]
Research Direction:Neural mechanism of social behavior
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Jiahui Lv Postdoctor
Email:[email protected]
Research Direction:Effects of microglia on brain development
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Liang Jun Master Degree Candidate
Email:[email protected]
Research Direction:Neural mechanism of sleep?
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Yang Li research assistant
Email:[email protected]
Research Direction:Neurometabolic basis of anorexia nervosa
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?Meng Wang
Email:[email protected]
Research Direction:1. Central regulatory mechanisms of anorexia nervosa; 2. Molecular mechanisms of central inflammation and metabolic disorders induced by the obesity gene MC4R
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Xuan Zhao
Email:[email protected]
Research Direction:Molecular biochemical experiments
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Han, Y., He, Y., Harris, L., Xu, Y., Wu, Q. (2023) Reversal of obesogenic feeding and hypometabolism by a bifurcating GABAergic neural circuit. eLife.
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Han, Y., Xia, G., He, Y., Farias, M., Xu, Y., Wu, Q.(2021) A hindbrain dopaminergic neural circuit prevents weight gain by reinforcing food satiation. Sci. Adv. 7(22):eabf8719.
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Han, Y#. , Xia, G#., Srisai, D#., Meng, F., He, Y., Ran, Y., Farias, M., Hoang, G., Toth, I., Dietrich, M., Chen, MH.,Xu, Y., Wu, Q. (2021) Deciphering a novel neural circuit in distinct control of energy metabolism from feeding. Nat Commun. 12(1):3525. (#co-first author)
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Xia, G#., Han, Y#.,Meng, F., He, Y., Srisai, D., Farias, M., Dang, M., Xu, Y., Palmiter, RD., Wu, Q. (2021) Reciprocal control of obesity and anxiety–depressive disorder via a novel GABAAR and 5-HT3R pathways. Mol. Psychiatry. doi: 10.1038/s41380-021-01053-w. (#co-first author)
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Han, Y., Xia, G. &Wu, Q. (2018) Functional interrogation of the AgRP neural circuits in control of appetite, body weight, and behaviors. Adv. Exp. Med. Biol. 1090:1-16.
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Han, Y., Huang, M., Sun, M., Duan, S.& Yu, Y. (2015) Long-term synaptic plasticity in rat barrel cortex. Cereb. Cortex. 25(9):2741-51.
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Han, Y., Shi, Y., Xi, W., Zhou, R., Tan, Z., Wang, H., Li, X., Chen, Z., Feng, G., Luo, M., Huang, Z., Duan, S. & Yu, Y. (2014) Selective activation of cholinergic basal forebrain neurons induces immediate sleep-wake transitions. Curr. Biol. 24: 693-698.
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Han, Y., Yu, H., Sun, M., Wang, Y., Xi, W., Yu, Y.(2014) Astrocyte-restricted disruption of connexin-43 impairs neuronal plasticity in mouse barrel cortex. Eur. J. Neurosci. 39: 35-45.
