郵箱：[email protected]
研究方向：細(xì)胞死亡和炎癥在人類疾病中的作用機(jī)制研究
教育經(jīng)歷：
2019.9-2023.7 同濟(jì)大學(xué) 臨床醫(yī)學(xué)（神經(jīng)生物學(xué)方向）博士
2011.9-2014.3 浙江理工大學(xué) 生物化學(xué)與分子生物學(xué) 碩士
2007.9-2011.6 浙江理工大學(xué) 生物技術(shù) 本科
工作經(jīng)歷：
2017.10-2019.8 同濟(jì)大學(xué)醫(yī)學(xué)院 科研助理
2014.05-2017.8 浙江我武生物科技股份有限公司（上海分公司） 學(xué)術(shù)專員
文章發(fā)表：
(1) Ruilong Xia et al. MiR-96 promotes maintenance of hearing and protects hearing against noise. (文章準(zhǔn)備投稿中);
(2) Li Ting Sun#, Rui Long Xia #, Jin Wen Jiang, Ting Wen, Zhuo Ya Huang, Ran Qian, Ming-Dong Zhang, Ming Cheng Zhou, Chang Geng Peng. MicroRNA-96 is required to prevent allodynia by repressing voltage-gated sodium channels in spinal cord. Progress in Neurobiology, 2021,202:102024 (共同第一作者，Q1);
(3) Li ting Sun#, Hang Xian#, Yun xin Shi#, Tao tan Yang#, Hongyan Shuai#, Ruilong Xia, Ting Wen, Wei Xia, Ran Qian, Feng ting Zhu, Yuan ying Liu, Zhi cheng Tian, Lamei Li, Rui Cong, Ceng Luo, Shengxi Wu, Xia feng Shen, Xin Yu, Rou-Gang Xie, Chang geng Peng. Nav1.7 and Nav1.8 form supramolecular
active clusters with TRKB in mouse and human DRG neurons during development of neuropathic pain.
(https://www.medrxiv.org/content/10.1101/2022.11.05.22281929v1)(預(yù)印版)；
(4) Rui Long Xia, Cai-Yun Fu, Shi-Fu Zhang, Yuan-Ting Jin, Fu-Kun Zhao. Study on the distribution sites and the molecular mechanism of analgesia after intracerebroventricular injection of rat/mouse hemokinin- 1 in mice. Peptides, 2013, 43:113-120. (Q2);
(5) Rui Long Xia #, Yan Lu #, Li Na Zhu, Shi Fu Zhang, Fu Kun Zhao, Cai Yun Fu. Different regulatory pathways are involved in the proliferative inhibition of two types of leukemia cell lines induced by paclitaxel. Oncology Reports, 2013, 30:1853-1859. (Q3);
(6) Cai Yun Fu, Rui Long Xia, Teng Fei Zhang, Yan Lu, Shi Fu Zhang, Zhi Qiang Yu, Tao Jin, Xiao Zhou Mou. Hemokinin-1(4-11)-induced analgesia selectively up-regulates δ-opioid receptor expression in mice. PLOS ONE, 2014, 9(2): e90446.doi:10.1371/journal.pone.0090446. (導(dǎo)師為第一作者，Q2);
(7) Yan Fu, Li ting Sun, Feng ting Zhu, Wei Xia, Ting Wen, Ruilong Xia, Xin Yu, Dan Xu, Chang geng Peng. Nav1.7 in spinal dorsal horn neurons induced by NGF contributes to neuropathic pain in a mouse spinal cord injury model. Front Mol Neurosci. 2023;16:1091096.（Q1）;
(8) Rong chuan Zhao, Jiao Yang, Yun jiao Zhai, Hong Zhang, Yuan shuai Zhou, Lei Hong, De tian Yuan, Ruilong Xia, Yan xiang Liu, Guohua Shi, Ruo bing Zhang, Ding san Luo, Jin yun Yuan, Chang geng Peng, Shi yang Li, Min xuan Sun. Nucleophosmin 1 promotes mucosal immunity by supporting mitochondrial oxidative phosphorylation and ILC3 activity.（Nature Immunology 審稿中）;
(9) Zhi bin Yan, Xiang yu Hong, Qi hao Lin, Lei jie Wang, Gang Shao, Chen tao Ge, Ruilong Xia, Cai yun Fu. Neurokinin-2 receptor antagonist SR48968 induced necroptosis of myeloid leukemia cells by calcium overload-driven reactive oxygen species accumulation. Genes & Diseases.（已接收）
專利情況：
（1）一種鎮(zhèn)痛止癢的藥物組合物及其使用方法，2021-01-15，WIPO，申請?zhí)枺?/span>WOCN21072071（發(fā)明專利，已轉(zhuǎn)讓）
（2）一種止痛止癢藥物組合物及其應(yīng)用方法， 2020-08-20，中國，專利號：ZL202010845095.2（發(fā)明專利，已轉(zhuǎn)讓）
（3）一種制備TrkB-tomato小鼠的方法及其應(yīng)用，2022-1-18，中國，申請?zhí)枺?/span>202210052495.7 （發(fā)明專利，已轉(zhuǎn)讓）
（4）Analgesic and antipruritic pharmaceutical composition and application method therefor，2023-8-3，澳大利亞，專利號：2021329457（已授權(quán)）
項(xiàng)目經(jīng)歷：
2018.2-2022.12一種鎮(zhèn)痛止癢的藥物組合物及其使用方法的研究
榮譽(yù)和獎(jiǎng)勵(lì):
(1)長三角神經(jīng)科學(xué)青年論壇，博士組“青鋒獎(jiǎng)”，2021
(2)浙江省普通高等學(xué)校優(yōu)秀畢業(yè)生，2014
(3)浙江理工大學(xué)優(yōu)秀畢業(yè)生，2014
(4)浙江理工大學(xué)優(yōu)秀畢業(yè)論文，2014
(5)第十三屆浙江省“挑戰(zhàn)杯” 競賽 省賽二等獎(jiǎng) 省區(qū)級（團(tuán)隊(duì)負(fù)責(zé)人），2013
(6)研究生國家獎(jiǎng)學(xué)金，2013
(7)第十三屆“挑戰(zhàn)杯” 全國大學(xué)生課外學(xué)術(shù)科技作品競賽“累進(jìn)創(chuàng)新獎(jiǎng)” 金獎(jiǎng)國家級（團(tuán)隊(duì)負(fù)責(zé)人），2013
(8)浙江省細(xì)胞學(xué)學(xué)會青年學(xué)者優(yōu)秀獎(jiǎng)，2013
當(dāng)前位置：
